The α_1b-Adrenoceptor Exists as a Higher-Order Oligomer: Effective Oligomerization Is Required for Receptor Maturation, Surface Delivery, and Function

Visualization of Interactions among bZIP and Rel Family Proteins in Living Cells Using Bimolecular Fluorescence Complementation

2002 • 1,516 citations

Organization of the G Protein-coupled Receptors Rhodopsin and Opsin in Native Membranes

2003 • 591 citations

Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET)

2006 • 521 citations

G Protein-Coupled Receptor Dimerization: Function and Ligand Pharmacology

2004 • 467 citations

Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation

2005 • 435 citations

Visualization of molecular interactions by fluorescence complementation

2006 • 423 citations

Homodimerization of the β2-Adrenergic Receptor as a Prerequisite for Cell Surface Targeting

2004 • 291 citations

Export from the Endoplasmic Reticulum Represents the Limiting Step in the Maturation and Cell Surface Expression of the Human δ Opioid Receptor

2000 • 285 citations

The Fourth Transmembrane Segment Forms the Interface of the Dopamine D2 Receptor Homodimer

2003 • 285 citations

Crosstalk in G protein-coupled receptors: Changes at the transmembrane homodimer interface determine activation

2005 • 282 citations

Structure-based Analysis of GPCR Function: Evidence for a Novel Pentameric Assembly between the Dimeric Leukotriene B4 Receptor BLT1 and the G-protein

2003 • 270 citations

Pharmacologic Rescue of Conformationally‐Defective Proteins: Implications for the Treatment of Human Disease

2004 • 253 citations

Oligomerization of G Protein-Coupled Receptors: Past, Present, and Future

2004 • 229 citations

The G protein‐coupled receptor rhodopsin in the native membrane

2004 • 224 citations

FRET imaging reveals that functional neurokinin-1 receptors are monomeric and reside in membrane microdomains of live cells

2006 • 220 citations

Methods to monitor the quaternary structure of G protein‐coupled receptors

2005 • 206 citations

Three-chromophore FRET microscopy to analyze multiprotein interactions in living cells

2004 • 186 citations

Identification of amino acid residues crucial for chemokine receptor dimerization

2004 • 184 citations

The regulatory mechanisms of export trafficking of G protein-coupled receptors

2005 • 146 citations

The CXCR1 and CXCR2 Receptors Form Constitutive Homo- and Heterodimers Selectively and with Equal Apparent Affinities

2005 • 133 citations

D2 Dopamine Receptor Homodimerization Is Mediated by Multiple Sites of Interaction, Including an Intermolecular Interaction Involving Transmembrane Domain 4

2003 • 131 citations

G-protein-coupled receptor heterodimers: pharmacology, function and relevance to drug discovery

2006 • 130 citations

Pharmacological chaperone action on G-protein-coupled receptors

2004 • 126 citations

DsRed as a Potential FRET Partner with CFP and GFP

2003 • 104 citations

Multiple Interactions between Transmembrane Helices Generate the Oligomeric α_1b-Adrenoceptor

2004 • 100 citations

Rhodopsin self-associates in asolectin liposomes

2006 • 95 citations

The Two-State Dimer Receptor Model: A General Model for Receptor Dimers

2006 • 80 citations

Inefficient Maturation of the Rat Luteinizing Hormone Receptor

2005 • 77 citations

Cellular Trafficking of Human α_1a-Adrenergic Receptors Is Continuous and Primarily Agonist-Independent

2004 • 62 citations

Oligomeric potential of the M₂ muscarinic cholinergic receptor

2004 • 60 citations

Protein Folding as Posttranslational Regulation: Evolution of a Mechanism for Controlled Plasma Membrane Expression of a G Protein-Coupled Receptor

2006 • 58 citations

Silencing of secretin receptor function by dimerization with a misspliced variant secretin receptor in ductal pancreatic adenocarcinoma.

2002 • 58 citations

β-Arrestin-Dependent Spontaneous α_1a-Adrenoceptor Endocytosis Causes Intracellular Transportation of α-Blockers via Recycling Compartments

2004 • 44 citations

Microscopic Analysis of Fluorescence Resonance Energy Transfer (FRET)

2004 • 34 citations

Oligomers of D<SUB>2</SUB> Dopamine Receptors: Evidence From Ligand Binding

2005 • 23 citations

Co- and Posttranslational Modification of the α_1B-Adrenergic Receptor: Effects on Receptor Expression and Function

2002 • 16 citations

A framework for computational and experimental methods: Identifying dimerization residues in CCR chemokine receptors

2005 • 14 citations