Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli.

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

1988 • 1,711 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.

1986 • 1,079 citations

Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.

1988 • 990 citations

Interleukin-1 receptor antagonist reduces mortality from endotoxin shock

1990 • 865 citations

Circulating Interleukin-1 and Tumor Necrosis Factor in Septic Shock and Experimental Endotoxin Fever

1990 • 765 citations

Tumor Necrosis Factor and Interleuktn-1 in the Serum of Children with Severe Infectious Purpura

1988 • 735 citations

Sepsis syndrome: a valid clinical entity. Methylprednisolone Severe Sepsis Study Group.

1989 • 709 citations

Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia.

1989 • 651 citations

Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits.

1988 • 603 citations

An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin 1, and tumor necrosis factor-alpha increases neutrophil adherence by a CDw18-dependent mechanism.

1986 • 593 citations

Cytokine appearance in human endotoxemia and primate bacteremia.

1988 • 528 citations

A specific receptor antagonist for interleukin 1 prevents Escherichia coli ‐induced shock in rabbits

1991 • 435 citations

Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog.

1987 • 425 citations

Lipoteichoic Acids: A New Class of Bacterial Antigen

1975 • 383 citations

Coagulase-Negative Staphylococcal Bacteremia

1989 • 354 citations

Nosocomial Septicemia Due to Multiply Antibiotic-Resistant Staphylococcus epidermidis

1982 • 330 citations

Platelet activating factor (PAF) involvement in endotoxin-induced hypotension in rats. studies with paf-receptor antagonist kadsurenone

1985 • 298 citations

Isolation and Characterization of a Capsular Polysaccharide Adhesin from Staphylococcus epidermidis

1988 • 267 citations

Effects of anti-C5a antibodies on the adult respiratory distress syndrome in septic primates.

1986 • 267 citations

Is platelet activating factor (PAF) a mediator of endotoxin shock?

1985 • 247 citations

Acute circulatory collapse caused by platelet-activating factor (PAF-acether) in dogs

1983 • 243 citations

Activation of the Properdin Pathway of Complement in Patients with Gram-Negative Bacteremia

1975 • 235 citations

Septic shock. Hemodynamics and pathogenesis.

1983 • 229 citations

Role of endotoxemia in cardiovascular dysfunction and mortality. Escherichia coli and Staphylococcus aureus challenges in a canine model of human septic shock.

1989 • 217 citations

C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha.

1988 • 216 citations

Acute inflammation and a Shwartzman-like reaction induced by interleukin-1 and tumor necrosis factor. Synergistic action of the cytokines in the induction of inflammation and microvascular injury.

1987 • 214 citations

C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gamma.

1987 • 195 citations

Endotoxin-induced shock in the rat. A role for C5a.

1989 • 182 citations

Preliminary report: effects of interleukin-1 on platelet counts

1990 • 164 citations

Hospital-acquired bloodstream infections with staphylococcus epidermidis

1984 • 150 citations

Interleukin-1 beta in human plasma: optimization of blood collection, plasma extraction, and radioimmunoassay methods.

1988 • 122 citations

Interleukin-l Induces Tumor Necrosis Factor (TNF) in Human Peripheral Blood Mononuclear Cells In Vitro and a Circulating TNF-Iike Activity in Rabbits

1990 • 119 citations

Role of interleukin 1 and tumor necrosis factor on energy metabolism in rabbits

1988 • 105 citations

Induction by Toxic-Shock-Syndrome Toxin-1 of a Circulating Tumor Necrosis Factor-Like Substance in Rabbits and of Immunoreactive Tumor Necrosis Factor and Interleukin-1 from Human Mononuclear Cells

1988 • 99 citations

Observations on the Measurement and Evaluation of Endotoxemia by a Quantitative Limulus Lysate Microassay

1984 • 95 citations

C5a-induced hemodynamic and hematologic changes in the rabbit. Role of cyclooxygenase products and polymorphonuclear leukocytes.

1987 • 66 citations

Rabbit IL-1. Cloning, expression, biologic properties, and transcription during endotoxemia.

1989 • 64 citations

Anaphylatoxin‐induced shock and two patterns of anaphylactic shock: Hemodynamics and mediators*

1979 • 50 citations

Staphylococcus epidermidis Sepsis in Surgical Patients

1984 • 48 citations

Hemodynamic Measurements in Bacteremia and Septic Shock in Man

1973 • 44 citations

Interleukin-1 and tumour necrosis factor cause hypotension in the conscious rabbit

1988 • 42 citations

Coagulase-negative staphylococcal bacteremia. Mortality and hospital stay

1990 • 41 citations

Septic shock. Hemodynamics and pathogenesis

1983 • 40 citations

Coagulase-Negative Staphylococci

1989 • 27 citations

Experimental Bacteroides fragilis Bacteremia in a Primate Model

1985 • 23 citations

Endogenous pyrogen production by human blood monocytes stimulated by staphylococcal cell wall components

1981 • 20 citations

Hospital-acquired bloodstream infections with Staphylococcus epidermidis: Review of 100 cases

1985 • 7 citations