Smad Expression in Human Atherosclerotic Lesions

A Definition of Advanced Types of Atherosclerotic Lesions and a Histological Classification of Atherosclerosis

1995 • 3,361 citations

TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders

2000 • 2,354 citations

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

1993 • 1,941 citations

Direct binding of Smad3 and Smad4 to critical TGFbeta -inducible elements in the promoter of human plasminogen activator inhibitor-type 1gene

1998 • 1,763 citations

Abrogation of TGFβ Signaling in T Cells Leads to Spontaneous T Cell Differentiation and Autoimmune Disease

2000 • 970 citations

Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

1999 • 912 citations

Transforming Growth Factor‐β

1990 • 696 citations

Identification of Novel TGF-β/Smad Gene Targets in Dermal Fibroblasts using a Combined cDNA Microarray/Promoter Transactivation Approach

2001 • 628 citations

Transforming Growth Factor-β Signaling Through the Smad Pathway: Role in Extracellular Matrix Gene Expression and Regulation

2002 • 622 citations

Apoptosis inhibitory activity of cytoplasmic p21Cip1/WAF1 in monocytic differentiation

1999 • 587 citations

Interdependent SMAD and JNK Signaling in Transforming Growth Factor-β-mediated Transcription

1999 • 534 citations

TGFβ influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

2001 • 479 citations

Inhibition of Transforming Growth Factor-β Signaling Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Mice

2001 • 474 citations

CTGF and SMADs, Maintenance of Scleroderma Phenotype Is Independent of SMAD Signaling

2001 • 419 citations

Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15Ink4B transcription in response to TGF-β

2000 • 392 citations

Role of Smad Proteins and Transcription Factor Sp1 in p21Waf1/Cip1 Regulation by Transforming Growth Factor-β

2000 • 389 citations

TGF-β1-mediated fibroblast–myofibroblast terminal differentiation—the role of smad proteins

2003 • 360 citations

Expression of Neutrophil Collagenase (Matrix Metalloproteinase-8) in Human Atheroma

2001 • 341 citations

Transforming Growth Factor-β Mediates Balance Between Inflammation and Fibrosis During Plaque Progression

2002 • 311 citations

Comparison of Apolipoprotein and Proteoglycan Deposits in Human Coronary Atherosclerotic Plaques

1998 • 271 citations

Transforming Growth Factor β-Independent Shuttling of Smad4 between the Cytoplasm and Nucleus

2000 • 266 citations

Localization and production of plasminogen activator inhibitor-1 in human healthy and atherosclerotic arteries.

1993 • 264 citations

Transforming Growth Factor-β Repression of Matrix Metalloproteinase-1 in Dermal Fibroblasts Involves Smad3

2001 • 247 citations

Alternatively Spliced Variant of Smad2 Lacking Exon 3

1999 • 235 citations

Modulation of Smad2-mediated Signaling by Extracellular Signal-regulated Kinase

2002 • 194 citations

Distinct Patterns of Transforming Growth Factor-β Isoform and Receptor Expression in Human Atherosclerotic Lesions

1999 • 156 citations

Eplerenone Suppresses Constrictive Remodeling and Collagen Accumulation After Angioplasty in Porcine Coronary Arteries

2001 • 144 citations

Transforming growth factor-beta1 up-regulates p15, p21 and p27 and blocks cell cycling in G1 in human prostate epithelium

1999 • 103 citations

Cytochromeb₅₅₈–Dependent NAD(P)H Oxidase–Phox Units in Smooth Muscle and Macrophages of Atherosclerotic Lesions

2002 • 102 citations

Stage-Specific Expression of Smad2 and Smad3 During Folliculogenesis1

2002 • 81 citations

Transforming growth factor beta 1 stimulates type V collagen expression in bovine vascular smooth muscle cells

1994 • 79 citations

Smad4/DPC4-dependent Regulation of Biglycan Gene Expression by Transforming Growth Factor-β in Pancreatic Tumor Cells

2002 • 74 citations

p21cip1 mRNA is controlled by endogenous transforming growth factor-?1 in quiescent human hematopoietic stem/progenitor cells

2000 • 52 citations

p21Cip-1/SDI-1/WAF-1 Gene Is Involved in Chondrogenic Differentiation of ATDC5 Cells in Vitro

2001 • 50 citations

Collagen-synthesizing cells in initial and advanced atherosclerotic lesions of human aorta

1997 • 49 citations

Expression of p15ink4b gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors

2001 • 42 citations

Reconstitution of Lethally Irradiated Adult Mice with Dominant Negative TGF-β Type II Receptor-Transduced Bone Marrow Leads to Myeloid Expansion and Inflammatory Disease

2002 • 40 citations

Smad expression of hepatic stellate cells in liver cirrhosis in vivo and hepatic stellate cell line in vitro

2003 • 21 citations

Burn-Induced Thymic Apoptosis Corresponds with Altered TGF-β1 and Smad 2/3

2002 • 17 citations