Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

Rapid Isolation of Antigens from Cells with A Staphylococcal Protein A-Antibody Adsorbent: Parameters of the Interaction of Antibody-Antigen Complexes with Protein A

1975 • 3,054 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

Fluorographic detection of radioactivity in polyacrylamide gols with the water-soluble fluor, sodium salicylate

1979 • 1,976 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system

1982 • 680 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine

1980 • 539 citations

Cloned Viral Protein Vaccine for Foot-and-Mouth Disease: Responses in Cattle and Swine

1981 • 504 citations

Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: Studies with cloned viral DNA

1980 • 474 citations

Tapping the immunological repertoire to produce antibodies of predetermined specificity

1982 • 473 citations

Lymphosarcoma: virus-induced thymic-independent disease in mice.

1970 • 414 citations

Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src).

1981 • 363 citations

Isolation of phosphorylated peptides and proteins on ion exchange papers

1978 • 359 citations

Analysis of adenovirus transforming proteins from early regions 1A and 1B with antisera to inducible fusion antigens produced in Escherichia coli

1984 • 349 citations

Extraction of nucleic acids from agarose gels

1980 • 346 citations

Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation.

1982 • 337 citations

Di-tert.-butyldicarbonat — ein vorteilhaftes Reagenz zur Einführung der tert.-Butyloxycarbonyl-Schutzgruppe

1976 • 294 citations

Direct transformation of 3T3 cells by Abelson murine leukaemia virus

1975 • 288 citations

Identification of an Abelson murine leukemia virus-encoded protein present in transformed fibroblast and lymphoid cells.

1978 • 266 citations

Antibodies specific for the carboxy- and amino-terminal regions of simian virus 40 large tumor antigen.

1980 • 262 citations

Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other onc gene products with tyrosine-specific kinase activity.

1983 • 253 citations

In vitro transformation of lymphoid cells by Abelson murine leukemia virus.

1975 • 247 citations

Nucleotide sequence of Fujinami sarcoma virus: evolutionary relationship of its transforming gene with transforming genes of other sarcoma viruses

1982 • 239 citations

Evidence that the avian sarcoma virus transforming gene product is a cyclic AMP-independent protein kinase.

1979 • 232 citations

Viral src gene products are related to the catalytic chain of mammalian cAMP-dependent protein kinase.

1982 • 225 citations

Chemical synthesis of a polypeptide predicted from nucleotide sequence allows detection of a new retroviral gene product

1980 • 203 citations

Local mutagenesis of Rous sarcoma virus: The major sites of tyrosine and serine phosphorylation of p60src are dispensable for transformation

1983 • 189 citations

Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase.

1981 • 188 citations

In vitro phosphorylation of angiotensin analogs by tyrosyl protein kinases.

1983 • 186 citations

Characterization of mouse monoclonal antibodies specific for friend murine leukemia virus-induced erythroleukemia cells: Friend-specific and FMR-specific antigens

1981 • 184 citations

Sequences of the A-MuLV protein needed for fibroblast and lymphoid cell transformation

1983 • 165 citations

Mutants of Escherichia coli with an Altered Tryptophanyl-Transfer Ribonucleic Acid Synthetase

1968 • 147 citations

A normal cell protein cross-reactive to the major Abelson murine leukaemia virus gene product

1979 • 146 citations

Phosphorylation of tyrosine-416 is not required for the transforming properties and kinase activity of pp60v-src

1983 • 138 citations

Cells nonproductively transformed by Abelson murine leukemia virus express a high molecular weight polyprotein containing structural and nonstructural components.

1978 • 132 citations

A transformation-defective mutant of Abelson murine leukemia virus lacks protein kinase activity.

1980 • 132 citations

Oncogenes

1982 • 126 citations

Preparation of syngeneic tumor regressor serum reactive with the unique determinants of the Abelson murine leukemia virus-encoded P120 protein at the cell surface

1979 • 118 citations

Evidence that the Abelson virus protein functions in vivo as a protein kinase that phosphorylates tyrosine.

1981 • 113 citations

Antibodies against synthetic peptides as a tool for functional analysis of the transforming protein pp60src

1983 • 103 citations

Abelson murine leukemia virus mutants deficient in kinase activity and lymphoid cell transformation

1980 • 101 citations

Lethal effect of the abelson murine leukemia virus transforming gene product

1981 • 101 citations

Antibodies to a defined region of pp60src neutralize the tyrosine-specific kinase activity.

1983 • 99 citations

Expression of an Abelson murine leukemia virus-encoded protein in Escherichia coli causes extensive phosphorylation of tyrosine residues.

1982 • 99 citations

Structure of the abelson murine leukemia virus genome

1979 • 88 citations

In vivo tyrosine phosphorylations of the abelson virus transforming protein are absent in its normal cellular homolog

1982 • 86 citations

Homology between phosphotyrosine acceptor site of human c-abl and viral oncogene products

1983 • 86 citations

Genome structure of Abelson murine leukemia virus variants: proviruses in fibroblasts and lymphoid cells

1981 • 79 citations

Transfection of Fibroblasts by Cloned Abelson Murine Leukemia Virus DNA and Recovery of Transmissible Virus by Recombination with Helper Virus

1982 • 78 citations

Abelson murine leukemia virus transformation-defective mutants with impaired P120-associated protein kinase activity

1980 • 69 citations

Site-directed deletions of Abelson murine leukemia virus define 3' sequences essential for transformation and lethality

1983 • 57 citations

Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virus

1983 • 33 citations

Antibodies of predetermined specificity detect two retroviral oncogene products and inhibit their kinase activities

1983 • 28 citations

[Di-tert.-butyl-dicarbonate, a useful tert.-Butyloxycardonylating reagent (author's transl)].

1976 • 17 citations