Evidence for functional homology in the F-actin binding domains of gelsolin and alpha-actinin: implications for the requirements of severing and capping.

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein

1988 • 1,501 citations

Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments.

1986 • 828 citations

Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring.

1990 • 522 citations

Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain

1986 • 477 citations

The structure and function of α-actinin

1989 • 421 citations

Actin-binding proteins

1991 • 289 citations

Modular organization of actin crosslinking proteins

1991 • 282 citations

Bundling of actin filaments by alpha-actinin depends on its molecular length.

1990 • 272 citations

Gelsolin: Calcium‐ and polyphosphoinositide‐regulated actin‐ modulating protein

1987 • 228 citations

Fimbrin is a homologue of the cytoplasmic phosphoprotein plastin and has domains homologous with calmodulin and actin gelation proteins.

1990 • 208 citations

Identification of a region in segment 1 of gelsolin critical for actin binding.

1990 • 205 citations

Expression of human plasma gelsolin in Escherichia coli and dissection of actin binding sites by segmental deletion mutagenesis.

1989 • 195 citations

Identification of critical functional and regulatory domains in gelsolin.

1989 • 194 citations

Analysis of the actin-binding domain of alpha-actinin by mutagenesis and demonstration that dystrophin contains a functionally homologous domain.

1992 • 182 citations

Gelsolin has three actin-binding sites.

1988 • 156 citations

Identification of a polyphosphoinositide-modulated domain in gelsolin which binds to the sides of actin filaments.

1988 • 148 citations

Sequence similarity of the amino-terminal domain of Drosophila beta spectrin to alpha actinin and dystrophin.

1989 • 148 citations

Expression of the N‐terminal domain of dystrophin in E. coli and demonstration of binding to F‐actin

1992 • 144 citations

Nucleotide sequence of pig plasma gelsolin

1988 • 136 citations

The Dictyostelium gelation factor shares a putative actin binding site with alpha-actinins and dystrophin and also has a rod domain containing six 100-residue motifs that appear to have a cross-beta conformation.

1989 • 132 citations

The identification and sequence of the actin-binding domain of human red blood cell beta-spectrin.

1990 • 123 citations

Pieces in the actin-severing protein puzzle

1988 • 112 citations

Identification of a short sequence essential for actin binding by Dictyostelium ABP-120.

1990 • 93 citations

Two of the three actin‐binding domains of gelsolin bind to the same subdomain of actin Implications for capping and severing mechanisms

1991 • 73 citations

Direct demonstration of actin filament annealing in vitro.

1988 • 72 citations

Domain structure in actin-binding proteins: expression and functional characterization of truncated severin.

1991 • 70 citations

Evidence that a 27-residue sequence is the actin-binding site of ABP-120

1991 • 59 citations

Characterization of actin- and lipid-binding domains in severin, a calcium-dependent F-actin fragmenting protein

1992 • 57 citations

Rate constants and equilibrium constants for binding of the gelsolin‐actin complex to the barbed ends of actin filaments in the presence and absence of calcium

1986 • 46 citations

Are the conserved sequences in segment 1 of gelsolin important for binding actin?

1992 • 45 citations

Chimeric and truncated gCap39 elucidate the requirements for actin filament severing and end capping by the gelsolin family of proteins.

1991 • 41 citations

Role of actin-binding proteins in cytoskeletal dynamics

1991 • 37 citations

Role of the N- and C-terminal actin-binding domains of gelsolin in barbed filament end capping

1991 • 22 citations

Molecular biology of actin binding proteins: evidence for a common structural domain in the F-actin binding sites of gelsolin and α-actinin

1991 • 10 citations