Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots

1984 • 2,189 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.

1986 • 632 citations

A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components. Purification and characterization.

1986 • 515 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes

1987 • 474 citations

Tryptase from human pulmonary mast cells. Purification and characterization.

1981 • 428 citations

Further studies on the activation of procollagenase, the latent precursor of bone collagenase. Effects of lysosomal cathepsin B, plasmin and kallikrein, and spontaneous activation

1977 • 389 citations

A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen

1979 • 350 citations

Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer.

1986 • 348 citations

Acid hydrolases and tryptase from secretory granules of dispersed human lung mast cells.

1981 • 332 citations

Increased Dermal Mast Cell Populations in Progressive Systemic Sclerosis: A Link in Chronic Fibrosis?

1985 • 251 citations

Articular mastocytosis in rheumatoid arthritis

1984 • 210 citations

Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinases

1988 • 199 citations

Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen

1985 • 195 citations

Regulation of the Mammalian Collagenases

1984 • 194 citations

Quantitation of human synovial mast cells in rheumatoid arthritis and other rheumatic diseases

1984 • 173 citations

Autocrine Induction of Collagenase by Serum Amyloid A-Like and β ₂ -Microglobulin-Like Proteins

1989 • 162 citations

Mast cell numbers in rheumatoid synovial tissues

1987 • 150 citations

Neutral metallo-proteinases of rabbit bone. Separation in latent forms of distinct enzymes that when activated degrade collagen, gelatin and proteoglycans

1978 • 149 citations

The precursor of a metalloendopeptidase from human rheumatoid synovial fibroblasts. Purification and mechanisms of activation by endopeptidases and 4-aminophenylmercuric acetate

1988 • 142 citations

Mast cells at sites of cartilage erosion in the rheumatoid joint.

1984 • 134 citations

Purification of an endogenous activator of procollagenase from rabbit synovial fibroblast culture medium.

1983 • 134 citations

Mast cell heterogeneity and hyperplasia in bleomycin-induced pulmonary fibrosis of rats.

1984 • 128 citations

Mast cells and matrix degradation at sites of tumour invasion in rat mammary adenocarcinoma

1986 • 121 citations

Evidence that human rheumatoid synovial matrix metalloproteinase 3 is an endogenous activator of procollagenase

1988 • 120 citations

Recent insights into the pathogenesis of the proliferative lesion in rheumatoid arthritis

1976 • 112 citations

Activation of latent rheumatoid synovial collagenase by human mast cell tryptase.

1988 • 112 citations

Mast cells, T cells and abnormal fibrosis

1985 • 107 citations

Characterization and functional studies of rheumatoid synovial mast cells: Activation by secretagogues, anti‐IgE, and a histamine‐releasing lymphokine

1986 • 100 citations

Degradation of type IX collagen by matrix metalloproteinase 3 (stromelysin) from human rheumatoid synovial cells

1989 • 98 citations

Immunoassay of tryptase from human mast cells

1986 • 80 citations

Identification of plasma kallikrein as an activator of latent collagenase in rheumatoid synovial fluid

1982 • 73 citations

Degradation of basement membranes by human matrix metalloproteinase 3 (stromelysin)

1988 • 63 citations

Multiple steps in the activation of the inactive precursor of bone collagenase by trypsin

1972 • 57 citations

Relationship of Procollagenase Activator, Stromelysin and Matrix Metalloproteinase 3

1988 • 50 citations

The activation of latent pig synovial collagenase

1981 • 45 citations

Disease distribution of synovial fluid mast cells and cytophagocytic mononuclear cells in inflammatory arthritis.

1985 • 44 citations

Purification and characterization of collagenase activator protein synthesized by articular cartilage

1986 • 32 citations

Procollagenase activator produced by rabbit uterine cervical fibroblasts

1987 • 28 citations

Treatment of periodontal disease in beagles with lodoxamide ethyl, an inhibitor of mast cell release

1985 • 20 citations

Human lung mast cell tryptase fails to activate procollagenase or degrade proteoglycan

1985 • 9 citations

The Role of Connective Tissue Degrading Enzymes in Human Pathology

2021 • 2 citations