The precursor of a metalloendopeptidase from human rheumatoid synovial fibroblasts. Purification and mechanisms of activation by endopeptidases and 4-aminophenylmercuric acetate

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase.

1985 • 625 citations

Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells.

1976 • 555 citations

The electrophoretically ‘slow’ and ‘fast’ forms of the α2-macroglobulin molecule

1979 • 530 citations

A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components. Purification and characterization.

1986 • 515 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Comparison of human stromelysin and collagenase by cloning and sequence analysis

1986 • 443 citations

Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts.

1985 • 344 citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

1986 • 339 citations

Polyacrylamide gel electrophoresis in sodium dodecyl sulfate-containing buffers using multiphasic buffer systems: Properties of the stack, valid Rf− measurement, and optimized procedure

1977 • 307 citations

The complete primary structure of human matrix metalloproteinase-3. Identity with stromelysin.

1988 • 227 citations

Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components

1983 • 222 citations

Human skin fibroblast procollagenase: mechanisms of activation by organomercurials and trypsin

1983 • 208 citations

Binding of plasminogen to extracellular matrix.

1986 • 175 citations

Neutral proteases capable of proteoglycan digesting activity in osteoarthritic and normal human articular cartilage

1984 • 166 citations

Neutral metallo-proteinases of rabbit bone. Separation in latent forms of distinct enzymes that when activated degrade collagen, gelatin and proteoglycans

1978 • 149 citations

Human fibroblast collagenase: glycosylation and tissue-specific levels of enzyme synthesis.

1986 • 125 citations

Rabbit skeletal muscle calcium-dependent protease requiring millimolar CA2+. Purification, subunit structure, and Ca2+-dependent autoproteolysis.

1982 • 114 citations

Biosynthesis and secretion of procollagenase by rabbit synovial fibroblasts. Inhibition of procollagenase secretion by monensin and evidence for glycosylation of procollagenase

1983 • 102 citations

Human plasma kallikrein. A rapid purification method with high yield

1981 • 96 citations

The simultaneous release by bone explants in culture and the parallel activation of procollagenase and of a latent neutral proteinase that degrades cartilage proteoglycans and denatured collagen

1978 • 91 citations

Isolation of the Oncogene and Epidermal Growth Factor-Induced Transin Gene: Complex Control in Rat Fibroblasts

1986 • 90 citations

Intramolecular Activation of Porcine Pepsinogen

1971 • 89 citations

A precursor form of latent collagenase produced in a cell-free system with mRNA from rabbit synovial cells.

1981 • 88 citations

Autoproteolysis of the small subunit of calcium-dependent protease II activates and regulates protease activity.

1986 • 79 citations

Human gingival tissues in culture synthesize three metalloproteinases and a metalloproteinase inhibitor

1982 • 73 citations

Effect of tensile mechanical stress on the synthesis of metalloproteinases by rabbit coronal sutures in vitro

1980 • 66 citations

Interleukin 1 stimulation of synovial cell plasminogen activator production.

1986 • 46 citations

The role of subunit autolysis in activation of smooth muscle Ca2+-dependent proteases.

1986 • 45 citations

Activation in vitro of rheumatoid synovial collagenase from cell cultures.

1978 • 44 citations

Evidence for an intrazymogen mechanism in the conversion of proacrosin into acrosin

1981 • 27 citations

Secretion of Plasminogen Activator by Rheumatoid and Nonrheumatoid Synovial Cells In Culture

1977 • 25 citations

Preparation of a Monospecific Antibody to Purified Rabbit Synovial Fibroblast Collagenase

1981 • 19 citations