Fetal liver organ cultures allow the proliferative expansion of pre-B receptor-expressing pre-B-II cells and the differentiation of immature and mature B cells in vitro

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Stimulation of B-cell progenitors by cloned murine interleukin-7

1988 • 826 citations

Expression and function of c-kit in hemopoietic progenitor cells.

1991 • 756 citations

Long-term culture of B lymphocytes and their precursors from murine bone marrow.

1982 • 612 citations

Lymphoid Potential, Probed before Circulation in Mouse, Is Restricted to Caudal Intraembryonic Splanchnopleura

1996 • 591 citations

A critical role of λ5 protein in B cell development

1992 • 583 citations

Nucleotide sequence of a full-length cDNA for mousecytosketetal β-actin raRNA

1986 • 556 citations

A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication.

1981 • 531 citations

Expression and function of the interleukin 7 receptor in murine lymphocytes.

1993 • 496 citations

Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences.

1990 • 414 citations

The SCID but Not the RAG-2 Gene Product Is Required for Sμ–Sε Heavy Chain Class Switching

1996 • 411 citations

Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody.

1993 • 345 citations

Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.

1991 • 335 citations

Clonal growth and maturation to immunoglobulin secretion in vitro of every growth-inducible B lymphocyte

1977 • 309 citations

Use of Monoclonal Anti-mouse Immunoglobulin to Detect Mouse Antibodies

1981 • 252 citations

Studies on T cell maturation on defined thymic stromal cell populations in vitro.

1992 • 249 citations

A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors.

1996 • 236 citations

Analysis of the B-cell progenitor compartment at the level of single cells

1994 • 232 citations

In vitro generation of B lymphocytes in mouse foetal liver, a mammalian ‘bursa equivalent’

1974 • 210 citations

Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocytes in vitro.

1994 • 197 citations

Positive and negative selection events during B lymphopoiesis

1995 • 195 citations

The status of Ig loci rearrangements in single cells from different stages of B cell development

1995 • 186 citations

B lymphopoiesis on stromal cell clone: stromal cell clones acting on different stages of B cell differentiation^*

1988 • 181 citations

Characterization of thymic stromal‐derived lymphopoietin (TSLP) in murine B cell development in vitro

1996 • 160 citations

Changes in frequencies of clonable pre B cells during life in different lymphoid organs of mice

1993 • 138 citations

Ontogeny of terminal deoxynucleotidyl transferase-positive cells in lymphohemopoietic tissues of rat and mouse.

1979 • 137 citations

Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci.

1993 • 135 citations

Self‐renewal of B‐1 lymphocytes is dependent on CD19

1996 • 132 citations

The effect of in vivo IL-7 deprivation on T cell maturation.

1995 • 132 citations

Administration of IL-7 to normal mice stimulates B-lymphopoiesis and peripheral lymphadenopathy.

1991 • 117 citations

B cell development in mice with a defective λ₅ gene

1993 • 104 citations

IL-7 transgenic mice: analysis of the role of IL-7 in the differentiation of thymocytes in vivo and in vitro

1995 • 95 citations

B lymphocyte development in fetal liver

1977 • 78 citations

Clonal proliferation unlinked to terminal deoxynucleotidyl transferase synthesis in thymocytes of young mice.

1983 • 74 citations

Flow microfluorometric analysis of mouse thymus development in vivo and in vitro

1983 • 71 citations

Isolation and characterization of bovine and mouse terminal deoxynucleotidyltransferase cDNAs expressible in mammalian cells

1986 • 55 citations

Differentiation potential of 14-day fetal mouse thymocytes in organ culture. Analysis of CD4/CD8-defined single-positive and double-negative cells.

1988 • 53 citations

Monoclonal antibodies specific for murine IgM. II. Activation of B lymphocytes by monoclonal antibodies specific for the four constant domains of IgM

1985 • 51 citations

Selective peripheral expansion and activation of B cells expressing endogenous immunoglobulin in μ‐transgenic mice

1990 • 51 citations

Stimulation by T Cell Independent Antigens Can Relieve the Arrest of Differentiation of Immature Auto‐Reactive B Cells in the Bone Marrow*

1995 • 49 citations

Induction of sterile transcription from the kL chain gene locus in V(D)J recombinasedeficient progenitor B cells

1995 • 35 citations

A novel approach for preparing anti‐T cell receptor constant region antibodies

1986 • 34 citations

Stromal Cell Lines which Support Lymphocyte Growth

1991 • 19 citations

Relative expression of surface IgM, IgD and the Ig-associating alpha(mb-1) and beta(B-29) polypeptide chains.

1992 • 12 citations