Fluorescence Spectroscopy of Single Biomolecules

Semiconductor Nanocrystals as Fluorescent Biological Labels

1998 • 8,459 citations

Zwischenmolekulare Energiewanderung und Fluoreszenz

1948 • 7,839 citations

Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin

1997 • 3,163 citations

Overstretching B-DNA: The Elastic Response of Individual Double-Stranded and Single-Stranded DNA Molecules

1996 • 2,661 citations

Energy transfer: a spectroscopic ruler.

1967 • 1,865 citations

Single-Molecule Enzymatic Dynamics

1998 • 1,444 citations

Probing the interaction between two single molecules: fluorescence resonance energy transfer between a single donor and a single acceptor.

1996 • 1,203 citations

Illuminating Single Molecules in Condensed Matter

1999 • 1,102 citations

Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins

1998 • 1,094 citations

Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution

1995 • 1,029 citations

Sorting single molecules: application to diagnostics and evolutionary biotechnology.

1994 • 960 citations

Elasticity and unfolding of single molecules of the giant muscle protein titin

1997 • 735 citations

Direct observation of single kinesin molecules moving along microtubules

1996 • 709 citations

Single-Molecule Biomechanics with Optical Methods

1999 • 667 citations

OPTICAL STUDIES OF SINGLE MOLECULES AT ROOM TEMPERATURE

1998 • 610 citations

Decreased Resistance to Bacterial Infection and Granulocyte Defects in IAP-Deficient Mice

1996 • 599 citations

Direct Physical Measure of Conformational Rearrangement Underlying Potassium Channel Gating

1996 • 598 citations

Probing Single Molecule Dynamics

1994 • 580 citations

Single-molecule microscopy on model membranes reveals anomalous diffusion

1997 • 554 citations

Probing Individual Molecules with Confocal Fluorescence Microscopy

1994 • 539 citations

[13] Fluorescence resonance energy transfer

1995 • 513 citations

Detection of single fluorescent molecules

1990 • 473 citations

Simultaneous Observation of Individual ATPase and Mechanical Events by a Single Myosin Molecule during Interaction with Actin

1998 • 473 citations

Near-field spectroscopy of single molecules at room temperature

1994 • 428 citations

Proposed method for molecular optical imaging

1995 • 427 citations

OPTICAL DETECTION OF SINGLE MOLECULES

1997 • 406 citations

Imaging and Time-Resolved Spectroscopy of Single Molecules at an Interface

1996 • 404 citations

Three-Dimensional Imaging of Single Molecules Solvated in Pores of Poly(acrylamide) Gels

1996 • 373 citations

Protein trans -splicing by a split intein encoded in a split DnaE gene of Synechocystis sp. PCC6803

1998 • 359 citations

Monitoring conformational dynamics of a single molecule by selective fluorescence spectroscopy

1998 • 347 citations

Single‐Molecule Optical Detection, Imaging and Spectroscopy

1996 • 341 citations

Direct Measurement of Single-Molecule Diffusion and Photodecomposition in Free Solution

1997 • 340 citations

Alterations of Single Molecule Fluorescence Lifetimes in Near-Field Optical Microscopy

1994 • 338 citations

Single Molecule Dynamics Studied by Polarization Modulation

1996 • 337 citations

Differences in the chemical reactivity of individual molecules of an enzyme

1995 • 302 citations

Optical microscopic observation of single small molecules

1976 • 279 citations

Single Molecule Emission Characteristics in Near-Field Microscopy

1995 • 248 citations

Characterization of Photophysics and Mobility of Single Molecules in a Fluid Lipid Membrane

1995 • 247 citations

Single molecule detection and photochemistry on a surface using near-field optical excitation

1994 • 239 citations

Site-specific incorporation of biophysical probes into proteins.

1994 • 236 citations

Single-Molecule Fluorescence Analysis in Solution

1996 • 208 citations

Axial rotation of sliding actin filaments revealed by single-fluorophore imaging

1997 • 198 citations

3-Dimensional super-resolution by spectrally selective imaging

1998 • 197 citations

Studies on Single Alkaline Phosphatase Molecules: Reaction Rate and Activation Energy of a Reaction Catalyzed by a Single Molecule and the Effect of Thermal DenaturationThe Death of an Enzyme

1996 • 186 citations

Hindered Rotational Diffusion and Rotational Jumps of Single Molecules

1998 • 179 citations

Quantum efficiency independence of the time integrated emission from a fluorescent molecule

1976 • 169 citations

Single-Molecule Spectroscopy and Dynamics at Room Temperature

1996 • 160 citations

Role of the Kinesin Neck Region in Processive Microtubule-based Motility

1998 • 157 citations

Submillisecond detection of single rhodamine molecules in water

1994 • 156 citations

High-Speed DNA Sequencing: An Approach Based Upon Fluorescence Detection of Single Molecules

1989 • 156 citations

Attogram Detection Limit for Aqueous Dye Samples by Laser-Induced Fluorescence

1983 • 143 citations

Single-Molecule Identification of Coumarin-120 by Time-Resolved Fluorescence Detection: Comparison of One- and Two-Photon Excitation in Solution

1997 • 126 citations

Real time imaging of single fluorophores on moving actin with an epifluorescence microscope

1995 • 125 citations

Direct Observation of Ligand Colocalization on Individual Receptor Molecules

1998 • 107 citations

Monitoring the Reactions of Single Enzyme Molecules and Single Metal Ions

1997 • 104 citations

Time-resolved spectroscopy of single molecules using near-field and far-field optics

1996 • 101 citations

Single molecular assay of individual ATP turnover by a myosin‐GFP fusion protein expressed in vitro

1997 • 53 citations

Ultrasensitive laser-induced fluorescence detection in hydrodynamically focused flows

1987 • 52 citations

Dual-molecule spectroscopy: molecular rulers for the study of biological macromolecules

1996 • 45 citations

Site-specific mutagenesis with unnatural amino acids

1989 • 37 citations

Virometer: an optical instrument for visual observation, measurement and classification of free viruses.

1977 • 30 citations

Modeling fluorescence collection from single molecules in microspheres: effects of position, orientation, and frequency

1996 • 29 citations

Forty-First Annual Meeting March 2-6, 1997 Ernest N. Morial Convention Center New Orleans, Louisiana. Monday Symposia and Posters, Part I

1997 • 8 citations