Neuregulins and the Shaping of Synapses

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

Requirement for neuregulin receptor erbB2 in neural and cardiac development

1995 • 1,272 citations

Multiple essential functions of neuregulin in development

1995 • 1,236 citations

Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

1995 • 1,108 citations

The role of depolarization in the survival and differentiation of cerebellar granule cells in culture

1987 • 764 citations

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

1993 • 744 citations

Severe neuropathies in mice with targeted mutations in the ErbB3 receptor

1997 • 721 citations

Developmental changes in distribution of NMDA receptor channel subunit mRNAs

1992 • 718 citations

The anatomy of the cerebellum

1998 • 609 citations

Pattern electrical stimulation of the human retina

1999 • 592 citations

RETINAL WAVES AND VISUAL SYSTEM DEVELOPMENT

1999 • 544 citations

Disruption of experience-dependent synaptic modifications in striate cortex by infusion of an NMDA receptor antagonist

1990 • 497 citations

Neuregulins and Their Receptors: A Versatile Signaling Module in Organogenesis and Oncogenesis

1997 • 471 citations

ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2- and heregulin-deficient mice

1997 • 462 citations

Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases

1997 • 390 citations

Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4

1997 • 385 citations

Isoform-specific expression and function of neuregulin

1997 • 384 citations

Neuregulin and erbB Receptors Play a Critical Role in Neuronal Migration

1997 • 381 citations

Postsynaptic control of plasticity in developing somatosensory cortex

1993 • 341 citations

Hippocampal neuron loss in temporal lobe epilepsy: Correlation with early childhood convulsions

1987 • 325 citations

NMDA-receptor channel diversity in the developing cerebellum

1994 • 325 citations

Rescue of the Cardiac Defect in ErbB2 Mutant Mice Reveals Essential Roles of ErbB2 in Peripheral Nervous System Development

1999 • 321 citations

Cysteine-Rich Domain Isoforms of the Neuregulin-1 Gene Are Required for Maintenance of Peripheral Synapses

2000 • 309 citations

Involvement of the N -Methyl D-Aspartate (NMDA) Receptor in Synapse Elimination During Cerebellar Development

1992 • 308 citations

Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase

1999 • 307 citations

Ligands for ErbB-family receptors encoded by a neuregulin-like gene

1997 • 288 citations

Neu and its ligands: From an oncogene to neural factors

1993 • 286 citations

ARIA: A Neuromuscular Junction Neuregulin

1997 • 279 citations

Maintenance of Acetylcholine Receptor Number by Neuregulins at the Neuromuscular Junction in Vivo

1997 • 272 citations

Neuregulin-β induces expression of an NMDA-receptor subunit

1997 • 261 citations

The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses

2000 • 261 citations

Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development

1999 • 248 citations

Glutamate spillover suppresses inhibition by activating presynaptic mGluRs

2000 • 246 citations

Development of the Cerebellar System

1997 • 234 citations

Analysis of Relations between NMDA Receptors and GABA Release at Olfactory Bulb Reciprocal Synapses

2000 • 233 citations

Neuregulins in Development

1996 • 229 citations

Ablation of Cerebellar Golgi Cells Disrupts Synaptic Integration Involving GABA Inhibition and NMDA Receptor Activation in Motor Coordination

1998 • 226 citations

GABAA receptors display association of γ2-subunit with α1- and β2/3-subunits

1991 • 218 citations

Motor Discoordination Results from Combined Gene Disruption of the NMDA Receptor NR2A and NR2C Subunits, But Not from Single Disruption of the NR2A or NR2C Subunit

1996 • 189 citations

Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice

2000 • 181 citations

Role of neuregulins in glial cell development

2000 • 175 citations

Neuregulin induces GABA(A) receptor subunit expression and neurite outgrowth in cerebellar granule cells.

1999 • 160 citations

Gene regulation by patterned electrical activity during neural and skeletal muscle development

1999 • 144 citations

A Cysteine-Rich Isoform of Neuregulin Controls the Level of Expression of Neuronal Nicotinic Receptor Channels during Synaptogenesis

1998 • 143 citations

ErbB Tyrosine Kinases and the Two Neuregulin Families Constitute a Ligand-Receptor Network

1998 • 141 citations

ARIA/HRG regulates AChR epsilon subunit gene expression at the neuromuscular synapse via activation of phosphatidylinositol 3-kinase and Ras/MAPK pathway.

1996 • 131 citations

Heregulin-stimulated acetylcholine receptor gene expression in muscle: requirement for MAP kinase and evidence for a parallel inhibitory pathway independent of electrical activity

1997 • 130 citations

Neuregulin Induces GABA_AReceptor Subunit Expression and Neurite Outgrowth in Cerebellar Granule Cells

1999 • 130 citations

Neuregulins and neuregulin receptors in neural development

1997 • 120 citations

Characterization of a Neuregulin-Related Gene, Don-1, That Is Highly Expressed in Restricted Regions of the Cerebellum and Hippocampus

1997 • 114 citations

Synapse-specific and neuregulin-induced transcription require an Ets site that binds GABPα/GABPβ

1998 • 112 citations

Stimulation of the N-methyl-d-aspartate receptor promotes the biochemical differentiation of cerebellar granule neurons and not astrocytes

1989 • 110 citations

Neurotrophic effects of NMDA receptor activation on developing cerebellar granule cells

1993 • 106 citations

Activity-dependent regulation of Neu differentiation factor/neuregulin expression in rat brain

1998 • 105 citations

Transmembrane Neuregulins Interact with LIM Kinase 1, a Cytoplasmic Protein Kinase Implicated in Development of Visuospatial Cognition

1998 • 92 citations

Domain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tail

1998 • 92 citations

Understanding the origin of visual percepts elicited by electrical stimulation of the human retina

1999 • 91 citations

Expression patterns of transmembrane and released forms of neuregulin during spinal cord and neuromuscular synapse development

1999 • 89 citations

Differential Signaling by the Epidermal Growth Factor-like Growth Factors Neuregulin-1 and Neuregulin-2

1998 • 87 citations

NMDA-receptor antagonists disrupt the formation of the auditory space map in the mammalian superior colliculus

1995 • 72 citations

Genetic analysis of postsynaptic differentiation at the vertebrate neuromuscular junction

1997 • 72 citations

The Neuregulin Precursor proARIA Is Processed to ARIA after Expression on the Cell Surface by a Protein Kinase C-Enhanced Mechanism

1998 • 67 citations

Neuregulin-1 and Human Epidermal Growth Factor Receptors 2 and 3 Play a Role in Human Lung Development In Vitro

2000 • 65 citations

Release of the Neuregulin Functional Polypeptide Requires Its Cytoplasmic Tail

1998 • 61 citations

Identification of a neuregulin and protein-tyrosine phosphatase response element in the nicotinic acetylcholine receptor ɛ subunit gene: Regulatory role of an Ets transcription factor

1998 • 60 citations

Why Do Schwann Cells Survive in the Absence of Axons?

1999 • 58 citations

Roles of neuregulin in synaptogenesis between mossy fibers and cerebellar granule cells

2000 • 48 citations

Membrane depolarization and the expression of glutamate receptors in cerebellar granule cells

1991 • 44 citations

Expression of receptors for neuregulins, ErbB2, ErbB3 and ErbB4, in developing mouse cerebellum

1998 • 41 citations

Processing of ARIA and release from isolated nerve terminals

1999 • 18 citations

Multiple isoforms of neuregulin are expressed in developing rat dorsal root ganglia

1997 • 16 citations

New branches on the neuregulin family tree

1998 • 9 citations

The Connection between Granule Cells and Mossy Fibers Changes Dynamically during Postnatal Cerebellar Development

1997 • 1 citations