The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development

Mechanisms of angiogenesis

1997 • 5,696 citations

Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis

1997 • 3,470 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis

1996 • 2,844 citations

Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning

1996 • 1,969 citations

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

1995 • 1,808 citations

Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4

1998 • 1,663 citations

Vasculogenesis

1995 • 1,344 citations

Requirement for neuregulin receptor erbB2 in neural and cardiac development

1995 • 1,272 citations

Blood Vessel Formation: What Is Its Molecular Basis?

1996 • 1,242 citations

Multiple essential functions of neuregulin in development

1995 • 1,236 citations

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.

1994 • 979 citations

Vascular Dysmorphogenesis Caused by an Activating Mutation in the Receptor Tyrosine Kinase TIE2

1996 • 779 citations

flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors

1993 • 707 citations

Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo

1996 • 606 citations

Increased Microvascular Density and Enhanced Leukocyte Rolling and Adhesion in the Skin of VEGF Transgenic Mice

1998 • 552 citations

Fashioning the vertebrate heart: earliest embryonic decisions

1997 • 490 citations

Molecular Pathways Controlling Heart Development

1996 • 485 citations

Stabilization of Vascular Endothelial Growth Factor mRNA by Hypoxia and Hypoglycemia and Coregulation with Other Ischemia-Induced Genes

1995 • 453 citations

Mutations affecting the cardiovascular system and other internal organs in zebrafish

1996 • 441 citations

The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates

1990 • 430 citations

Transgenic Mice with Increased Expression of Vascular Endothelial Growth Factor in the Retina: A New Model of Intraretinal and Subretinal Neovascularization.

1998 • 367 citations

Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization.

1995 • 338 citations

Chick Ovalbumin Upstream Promoter-Transcription Factors (COUP-TFs): Coming of Age*

1997 • 318 citations

Platelet endothelial cell adhesion molecule-1 (PECAM-1 / CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development

1994 • 301 citations

Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation.

1988 • 297 citations

Molecular Mechanisms of Action of Steroid/Thyroid Receptor Superfamily Members

1994 • 219 citations

Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization

1997 • 215 citations

TIE1 and TIE2 Receptor Tyrosine Kinases Inversely Regulate Embryonic Angiogenesis by the Mechanism of Intussusceptive Microvascular Growth

1998 • 209 citations

Development of the Aortic Vessel Wall as Defined by Vascular Smooth Muscle and Extracellular Matrix Markers

1996 • 196 citations

VEGF enhances pulmonary vasculogenesis and disrupts lung morphogenesis in vivo

1998 • 195 citations

Parsing the Heart: Genetic Modules for Organ Assembly

1997 • 163 citations

Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon.

1994 • 162 citations

Mediation of Sonic Hedgehog-Induced Expression of COUP-TFII by a Protein Phosphatase

1997 • 149 citations

Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors

1994 • 143 citations

Chick Ovalbumin Upstream Promoter-Transcription Factors (COUP-TFs): Coming of Age

1997 • 137 citations

Chicken ovalbumin upstream promoter transcription factor (COUP-TF): Expression during mouse embryogenesis

1995 • 118 citations

Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons

1994 • 96 citations

The Mouse Bone Morphogenetic Protein-4 Gene

1995 • 94 citations

Platelet Endothelial Cell Adhesion Molecule (CD31)

1993 • 90 citations

Functional conservation of vertebrate seven-up related genes in neurogenesis and eye development.

1993 • 83 citations

Isolation and Developmental Expression of Retinoic-Acid-Induced Genes

1994 • 66 citations

Color atlas of embryology

1995 • 60 citations

Identification of a Novel Sonic Hedgehog Response Element in the Chicken Ovalbumin Upstream Promoter-Transcription Factor II Promoter

1997 • 55 citations

Developmental expression and differential regulation by retinoic acid ofXenopus COUP-TF-A andCOUP-TF-B

1996 • 50 citations

Isolation, Characterization, and Chromosomal Localization of Mouse and Human COUP-TF I and II Genes

1995 • 48 citations

Gene therapy for therapeutic myocardial angiogenesis: A promising synthesis of two emerging technologies

1998 • 46 citations

Regulation of Oct-4 gene expression during differentiation of EC cells

1995 • 37 citations

A novel vertebrate svp-related nuclear receptor is expressed as a step gradient in developing rhombomeres and is affected by retinoic acid

1995 • 36 citations

Assessment of lymphokine profiles in activated lymphocytes by semiquantitative PCR

1993 • 20 citations

Identification of a Novel Sonic Hedgehog Response Element in the Chicken Ovalbumin Upstream Promoter-Transcription Factor II Promoter

1997 • 8 citations