Cognitive Reserve and Alzheimer Disease

What is cognitive reserve? Theory and research application of the reserve concept

2002 • 3,449 citations

Exercise Enhances Learning and Hippocampal Neurogenesis in Aged Mice

2005 • 2,005 citations

Aging Gracefully: Compensatory Brain Activity in High-Performing Older Adults

2002 • 1,875 citations

Leisure Activities and the Risk of Dementia in the Elderly

2003 • 1,813 citations

Influence of Education and Occupation on the Incidence of Alzheimer's Disease

1994 • 1,373 citations

Influence of social network on occurrence of dementia: a community-based longitudinal study

2000 • 1,310 citations

Participation in Cognitively Stimulating Activities and Risk of Incident Alzheimer Disease

2002 • 1,297 citations

Education and the prevalence of dementia and Alzheimer's disease

1993 • 1,154 citations

The prevalence of dementia and Alzheimer's disease in Shanghai, China: Impact of age, gender, and education

1990 • 977 citations

Late-Life Engagement in Social and Leisure Activities Is Associated with a Decreased Risk of Dementia: A Longitudinal Study from the Kungsholmen Project

2002 • 944 citations

Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice

2005 • 859 citations

Brain reserve capacity on symptom onset after brain injury: A formulation and review of evidence for threshold theory.

1993 • 809 citations

Influence of leisure activity on the incidence of Alzheimer’s Disease

2001 • 793 citations

Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis

2003 • 788 citations

Rates and risk factors for dementia and Alzheimer’s disease

1999 • 757 citations

Education modifies the relation of AD pathology to level of cognitive function in older persons

2003 • 539 citations

Rate of memory decline in AD is related to education and occupation

1999 • 515 citations

Evidence from Functional Neuroimaging of a Compensatory Prefrontal Network in Alzheimer's Disease

2003 • 493 citations

Predictors of cognitive change in older persons: MacArthur studies of successful aging.

1995 • 467 citations

Inverse relationship between education and parietotemporal perfusion deficit in Alzheimer's disease

1992 • 461 citations

Development of dementing illnesses in an 80‐year‐old volunteer cohort

1989 • 454 citations

Education and Other Measures of Socioeconomic Status and Risk of Incident Alzheimer Disease in a Defined Population of Older Persons

1997 • 433 citations

Social and Leisure Activities and Risk of Dementia: A Prospective Longitudinal Study

1995 • 409 citations

Brain Networks Associated with Cognitive Reserve in Healthy Young and Old Adults

2004 • 404 citations

Predictors of cognitive change in older persons: MacArthur studies of successful aging.

1995 • 393 citations

Differential regional dysfunction of the hippocampal formation among elderly with memory decline and Alzheimer's disease

1999 • 355 citations

Lifetime Antecedents of Cognitive Reserve

2003 • 354 citations

Education and rates of cognitive decline in incident Alzheimer's disease

2005 • 327 citations

Association of premorbid intellectual function with cerebral metabolism in Alzheimer's disease: implications for the cognitive reserve hypothesis

1997 • 323 citations

Level of education and change in cognitive function in a community population of older persons

1993 • 317 citations

Literacy and Memory Decline Among Ethnically Diverse Elders

2003 • 315 citations

In vivo brain size and intelligence

1991 • 289 citations

Premorbid Intellectual Functioning, Education, and Brain Size in Traumatic Brain Injury: An Investigation of the Cognitive Reserve Hypothesis

2003 • 279 citations

Incidence of Alzheimer’s disease in a rural community in India

2001 • 277 citations

Relationship between lifetime occupation and parietal flow

1995 • 277 citations

Cognitive Decline and Literacy Among Ethnically Diverse Elders

2005 • 269 citations

Prevalence of clinically diagnosed Alzheimer's disease and other dementing disorders

1990 • 268 citations

The effects of intelligence and education on the development of dementia. A test of the brain reserve hypothesis

1997 • 262 citations

Biological markers for therapeutic trials in Alzheimer’s disease

2003 • 256 citations

Association of Life Activities With Cerebral Blood Flow in Alzheimer Disease

2003 • 247 citations

Increased risk of mortality in alzheimer's disease patients with more advanced educational and occupational attainment

1995 • 242 citations

The Influence of Education on Clinically Diagnosed Dementia Incidence and Mortality Data From the Kungsholmen Project

2001 • 242 citations

Prevalence of Dementia and Its Subtypes in the Japanese American Population of King County, Washington State: The Kame Project

1996 • 240 citations

Incidence of Dementia and Alzheimer's Disease in Elderly Community Residents of South-Western France

1994 • 231 citations

The effect of education on the incidence of dementia and Alzheimer's disease in the Framingham Study

1995 • 220 citations

Variable effects of aging on frontal lobe contributions to memory

2002 • 217 citations

Cognitive Decline in Adulthood: An 11.5-Year Follow-Up of the Baltimore Epidemiologic Catchment Area Study

1999 • 203 citations

Incidence of Dementia in a Population Older Than 75 Years in the United Kingdom

1994 • 199 citations

Education and change in cognitive function

1995 • 196 citations

Marital status and risk of Alzheimer’s disease

1999 • 182 citations

Incidence and relative risk of dementia in an urban elderly population: findings of a prospective field study

1994 • 178 citations

Longitudinal application of cognitive function measures in a defined population of community-dwelling elders

1991 • 159 citations

EDUCATION AND DECLINE IN COGNITIVE PERFORMANCE: COMPENSATORY BUT NOT PROTECTIVE

1997 • 156 citations

Age, Education, and Changes in the Mini‐Mental State Exam Scores of Older Women: Findings from the Nun Study

1996 • 154 citations

Association of education with incidence of cognitive impairment in three established populations for epidemiologic studies of the elderly

1994 • 154 citations

Low education and childhood rural residence

2000 • 135 citations

Different brain networks mediate task performance in normal aging and AD

2000 • 118 citations

Lifetime principal occupation and risk of Alzheimer's disease in the Kungsholmen project

2003 • 113 citations

EDUCATION, SURVIVAL, AND INDEPENDENCE IN ELDERLY CATHOLIC SISTERS, 1936-1988

1989 • 112 citations

Covariance PET patterns in early Alzheimer's disease and subjects with cognitive impairment but no dementia: utility in group discrimination and correlations with functional performance

2004 • 100 citations

Occupation during life and risk of dementia in French elderly community residents

2001 • 97 citations

Reading ability, education, and cognitive status assessment among older adults in Harlem, New York City.

1999 • 94 citations

Midlife income, occupation, APOE status, and dementia

2002 • 94 citations

Education and Occupation as Risk Factors for Dementias of the Alzheimer and Ischemic Vascular Types

1995 • 92 citations

Predicting Cognitive Impairment in High‐Functioning Community‐Dwelling Older Persons: MacArthur Studies of Successful Aging

2002 • 92 citations

Occupation type as a predictor of cognitive decline and dementia in old age

1998 • 85 citations

Targeting Alzheimer amyloid plaques in vivo

2000 • 85 citations

Cognitive Reserve–Mediated Modulation of Positron Emission Tomographic Activations During Memory Tasks in Alzheimer Disease

2004 • 59 citations

Increased risk of mortality in Alzheimer's disease patients with higher education? A replication study

1997 • 57 citations

Cognitive reserve and mortality in dementia: the role of cognition, functional ability and depression

1999 • 53 citations

[Psychosocial risk factors for Alzheimer's disease].

1999 • 48 citations

Correlations of regional postmortem enzyme activities with premortem local glucose metabolic rates in alzheimer's disease

1990 • 44 citations

Frequency of Delta-F508 Mutation and XV2C/KM19 Haplotypes in Cuban Cystic Fibrosis Families

1995 • 35 citations

[Psychosocial risk factors of Alzheimer's disease].

1999 • 16 citations