Post-GWAS gene–environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79 000 women

Annotation of functional variation in personal genomes using RegulomeDB

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Design of the Women’s Health Initiative Clinical Trial and Observational Study

1998 • 2,456 citations

Genome-wide association study identifies novel breast cancer susceptibility loci

2007 • 2,342 citations

European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection

2002 • 1,707 citations

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

2013 • 1,051 citations

A Multiethnic Cohort in Hawaii and Los Angeles: Baseline Characteristics

2000 • 964 citations

Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor–positive breast cancer

2007 • 793 citations

A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms

2008 • 750 citations

Genome-wide association study identifies five new breast cancer susceptibility loci

2010 • 694 citations

Gene–environment-wide association studies: emerging approaches

2010 • 650 citations

NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses

2005 • 624 citations

A common coding variant in CASP8 is associated with breast cancer risk

2007 • 608 citations

The Nurses' Health Study: lifestyle and health among women

2005 • 552 citations

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)

2009 • 540 citations

Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1

2009 • 540 citations

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2

2009 • 483 citations

The American Cancer Society Cancer Prevention Study II Nutrition Cohort

2002 • 461 citations

Common variants on chromosome 5p12 confer susceptibility to estrogen receptor–positive breast cancer

2008 • 458 citations

The American Cancer Society Cancer Prevention Study II Nutrition Cohort

2002 • 401 citations

Baseline Characteristics of Participants in the Women's Health Study

2000 • 312 citations

The Melbourne Collaborative Cohort Study.

2002 • 307 citations

Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33

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A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer

2011 • 299 citations

Toxic and trace elements in tobacco and tobacco smoke.

1992 • 258 citations

Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

2012 • 255 citations

Novel Breast Cancer Susceptibility Locus at 9q31.2: Results of a Genome-Wide Association Study

2011 • 244 citations

Genome-Wide Gene-Environment Study Identifies Glutamate Receptor Gene GRIN2A as a Parkinson's Disease Modifier Gene via Interaction with Coffee

2011 • 220 citations

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11

2012 • 174 citations

Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients

2010 • 172 citations

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

2011 • 172 citations

Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function

2012 • 166 citations

Etiologic and early marker studies in the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial

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A candidate gene approach to searching for low-penetrance breast and prostate cancer genes

2005 • 163 citations

Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

2010 • 159 citations

Evidence of Gene–Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors

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Genome-Wide Association Study in East Asians Identifies Novel Susceptibility Loci for Breast Cancer

2012 • 156 citations

Interactions Between Genetic Variants and Breast Cancer Risk Factors in the Breast and Prostate Cancer Cohort Consortium

2011 • 154 citations

A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study

2012 • 141 citations

A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study

2007 • 133 citations

Gene–environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study

2010 • 121 citations

Gene-Environment Interactions in Genome-Wide Association Studies: A Comparative Study of Tests Applied to Empirical Studies of Type 2 Diabetes

2011 • 120 citations

Lead Exposure: A Contributing Cause of the Current Breast Cancer Epidemic in Nigerian Women

2010 • 110 citations

Risk of Estrogen Receptor–Positive and –Negative Breast Cancer and Single–Nucleotide Polymorphism 2q35-rs13387042

2009 • 107 citations

Gene‐Environment Interactions in Cancer Epidemiology: A National Cancer Institute Think Tank Report

2013 • 102 citations

Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium

2011 • 98 citations

Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study

2010 • 94 citations

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2mutation carriers

2012 • 93 citations

A genetic risk predictor for breast cancer using a combination of low-penetrance polymorphisms in a Japanese population

2011 • 90 citations

Genetic Susceptibility Loci for Subtypes of Breast Cancer in an African American Population

2012 • 86 citations

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

2011 • 76 citations

Metals and Breast Cancer: Risk Factors or Healing Agents?

2011 • 55 citations

Variation in the FGFR2 Gene and the Effects of Postmenopausal Hormone Therapy on Invasive Breast Cancer

2009 • 54 citations

Tobacco Smoke Exposure During Pregnancy Increases Maternal Blood Lead Levels Affecting Neonate Birth Weight

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Evidence of Genetic Effects on Blood Lead Concentration

2007 • 39 citations

11q13 is a susceptibility locus for hormone receptor positive breast cancer

2012 • 37 citations

Urinary Lead Exposure and Breast Cancer Risk in a Population-Based Case-Control Study

2008 • 33 citations

Genes–Environment Interactions in Obesity- and Diabetes-Associated Pancreatic Cancer: A GWAS Data Analysis

2013 • 33 citations

Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome–wide interaction study

2013 • 27 citations

The association between spatial distribution of common malignancies and soil lead concentration in Isfahan, Iran.

2012 • 9 citations