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Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

Data up to Jan 2025

Published2010
Citations159
References41

Total Citations Per Year

Abstract

References (41)

PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses

2007 • 29,581 citations

The behavior of maximum likelihood estimates under nonstandard conditions

1967 • 4,602 citations

Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies

2003 • 3,497 citations

The Robust Inference for the Cox Proportional Hazards Model

1989 • 2,407 citations

GenABEL: an R library for genome-wide association analysis

2007 • 1,767 citations

Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer

2003 • 938 citations

Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs

2008 • 791 citations

Genome-wide association study identifies five new breast cancer susceptibility loci

2010 • 694 citations

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions

2008 • 501 citations

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

2010 • 488 citations

A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes

2002 • 483 citations

Whole population, genome-wide mapping of hidden relatedness

2008 • 473 citations

Overcoming the Winner’s Curse: Estimating Penetrance Parameters from Case-Control Data

2007 • 378 citations

Susceptibility Pathways in Fanconi's Anemia and Breast Cancer

2010 • 364 citations

Content-rich biological network constructed by mining PubMed abstracts

2004 • 346 citations

Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study.

1996 • 337 citations

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

2010 • 332 citations

Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families

1996 • 320 citations

Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer

1996 • 306 citations

Evidence for further breast cancer susceptibility genes in addition to BRCA1 and BRCA2 in a population‐based study

2001 • 287 citations

Variation of Breast Cancer Risk Among BRCA1/2 Carriers

2008 • 284 citations

BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair

2010 • 282 citations

Common Breast Cancer-Predisposition Alleles Are Associated with Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

2008 • 281 citations

Estimation of the Inbreeding Coefficient through Use of Genomic Data

2003 • 247 citations

Management of an Inherited Predisposition to Breast Cancer

2007 • 244 citations

A Genomic Background Based Method for Association Analysis in Related Individuals

2007 • 244 citations

RAD51 135G→C Modifies Breast Cancer Risk among BRCA2 Mutation Carriers: Results from a Combined Analysis of 19 Studies

2007 • 238 citations

Genome-Wide Association Studies of Cancer

2010 • 181 citations

An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

2007 • 155 citations

A weighted cohort approach for analysing factors modifying disease risks in carriers of high‐risk susceptibility genes

2005 • 139 citations

Population-Based Study of Changing Breast Cancer Risk in Icelandic BRCA2 Mutation Carriers, 1920–2000

2006 • 132 citations

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

2009 • 115 citations

Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population

2006 • 90 citations

Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

2010 • 74 citations

Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers

2009 • 55 citations

Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping

2008 • 39 citations

CASP8 D302H polymorphism delays the age of onset of breast cancer in BRCA1 and BRCA2 carriers

2009 • 28 citations

The 6q22.33 Locus and Breast Cancer Susceptibility

2009 • 25 citations

Localization of breast cancer susceptibility loci by genome‐wide SNP linkage disequilibrium mapping

2005 • 24 citations

Common breast cancer predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

2008 • 22 citations

The CASP8 rs3834129 polymorphism and breast cancer risk in BRCA1 mutation carriers

2010 • 17 citations

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Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer (2010) – PLoS Genetics | Metascience Observatory Explorer