Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

Genome-wide association study identifies novel breast cancer susceptibility loci

2007 • 2,342 citations

Endogenous Sex Hormones and Breast Cancer in Postmenopausal Women: Reanalysis of Nine Prospective Studies

2002 • 1,729 citations

A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

2007 • 1,493 citations

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

2009 • 1,390 citations

Association of Risk-Reducing Surgery in <emph type="ital">BRCA1</emph> or <emph type="ital">BRCA2</emph> Mutation Carriers With Cancer Risk and Mortality

2010 • 1,361 citations

Endocrine-responsive breast cancer and strategies for combating resistance

2002 • 860 citations

The Pathology of Familial Breast Cancer: Predictive Value of Immunohistochemical Markers Estrogen Receptor, Progesterone Receptor, HER-2, and p53 in Patients With Mutations in BRCA1 and BRCA2

2002 • 809 citations

Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor–positive breast cancer

2007 • 793 citations

Control of mammary stem cell function by steroid hormone signalling

2010 • 650 citations

Progesterone induces adult mammary stem cell expansion

2010 • 641 citations

Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1

2009 • 540 citations

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)

2009 • 540 citations

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions

2008 • 501 citations

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2

2009 • 483 citations

Common variants on chromosome 5p12 confer susceptibility to estrogen receptor–positive breast cancer

2008 • 458 citations

Breast Cancer Risk Following Bilateral Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: An International Case-Control Study

2005 • 435 citations

Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics

2008 • 372 citations

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

2010 • 332 citations

Common Breast Cancer-Predisposition Alleles Are Associated with Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

2008 • 281 citations

Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: An update

2005 • 253 citations

RAD51 135G→C Modifies Breast Cancer Risk among BRCA2 Mutation Carriers: Results from a Combined Analysis of 19 Studies

2007 • 238 citations

On Generalized Score Tests

1992 • 231 citations

The nonsense-mediated mRNA decay pathway triggers degradation of most BRCA1 mRNAs bearing premature termination codons

2002 • 230 citations

Preventive therapy for breast cancer: a consensus statement

2011 • 213 citations

Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction

2010 • 179 citations

Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

2010 • 159 citations

An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

2007 • 155 citations

A weighted cohort approach for analysing factors modifying disease risks in carriers of high‐risk susceptibility genes

2005 • 139 citations

Mammographic Density and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

2006 • 129 citations

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

2009 • 115 citations

Ancestry-Shift Refinement Mapping of the C6orf97-ESR1 Breast Cancer Susceptibility Locus

2010 • 107 citations

Genetic modifiers of cancer risk for BRCA1 and BRCA2 mutation carriers

2011 • 88 citations

Replication and Functional Genomic Analyses of the Breast Cancer Susceptibility Locus at 6q25.1 Generalize Its Importance in Women of Chinese, Japanese, and European Ancestry

2011 • 76 citations

The 185delAG mutation (c.68_69delAG) in theBRCA1 gene triggers translation reinitiation at a downstream AUG codon

2006 • 61 citations

ESR1 Is Co-Expressed with Closely Adjacent Uncharacterised Genes Spanning a Breast Cancer Susceptibility Locus at 6q25.1

2011 • 58 citations

Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers

2009 • 55 citations

Genetic Variation at 9p22.2 and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers

2010 • 49 citations

Association of the VariantsCASP8D302H andCASP10V410I with Breast and Ovarian Cancer Risk inBRCA1andBRCA2Mutation Carriers

2010 • 41 citations

Common genetic variants and cancer risk in Mendelian cancer syndromes

2010 • 27 citations

The CASP8 rs3834129 polymorphism and breast cancer risk in BRCA1 mutation carriers

2010 • 17 citations

Identification of personal risk of breast cancer: genetics

2008 • 8 citations

Ovarian steroid hormones: what's hot in the stem cell pool?

2010 • 1 citations