Centrosome duplication: of rules and licenses

Hudson et al.

1977 • 2,560 citations

Proteomic characterization of the human centrosome by protein correlation profiling

2003 • 1,282 citations

The Primary Cilium as the Cell's Antenna: Signaling at a Sensory Organelle

2006 • 1,113 citations

The Ciliopathies: An Emerging Class of Human Genetic Disorders

2006 • 1,104 citations

Cleavage of Cohesin by the CD Clan Protease Separin Triggers Anaphase in Yeast

2000 • 799 citations

Zur Frage der Entstehung maligner Tumoren

1914 • 796 citations

The Polo kinase Plk4 functions in centriole duplication

2005 • 772 citations

Mammalian Cell Fusion : Studies on the Regulation of DNA Synthesis and Mitosis

1970 • 759 citations

Preventing re-replication of chromosomal DNA

2005 • 648 citations

SAK/PLK4 Is Required for Centriole Duplication and Flagella Development

2005 • 599 citations

Active cyclin B1–Cdk1 first appears on centrosomes in prophase

2003 • 587 citations

Centrosome composition and microtubule anchoring mechanisms

2002 • 557 citations

Pericentrin and γ-Tubulin Form a Protein Complex and Are Organized into a Novel Lattice at the Centrosome

1998 • 485 citations

Centrosome duplication in mammalian somatic cells requires E2F and Cdk2–Cyclin A

1999 • 476 citations

Mechanism limiting centrosome duplication to once per cell cycle

2006 • 426 citations

Centriole assembly in Caenorhabditis elegans

2006 • 392 citations

SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells

2005 • 380 citations

Centrioles in the cell cycle. I. Epithelial cells.

1982 • 362 citations

Centrosome-associated Chk1 prevents premature activation of cyclin-B–Cdk1 kinase

2004 • 334 citations

Rootletin forms centriole-associated filaments and functions in centrosome cohesion

2005 • 330 citations

Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells

1999 • 329 citations

Mechanisms and Molecules of the Mitotic Spindle

2004 • 318 citations

SAS-4 Is a C. elegans Centriolar Protein that Controls Centrosome Size

2003 • 316 citations

Cilia and centrosomes: a unifying pathogenic concept for cystic kidney disease?

2005 • 313 citations

The C. elegans zyg-1 Gene Encodes a Regulator of Centrosome Duplication with Distinct Maternal and Paternal Roles in the Embryo

2001 • 309 citations

Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells.

1995 • 301 citations

Centriole Assembly Requires Both Centriolar and Pericentriolar Material Proteins

2004 • 298 citations

Odf2-deficient mother centrioles lack distal/subdistal appendages and the ability to generate primary cilia

2005 • 293 citations

CENTROSOMES IN CELLULAR REGULATION

2005 • 292 citations

Spindle Assembly in Animal Cells

2000 • 281 citations

Centrosome amplification and the development of cancer

2002 • 277 citations

Cilia: Tuning in to the Cell's Antenna

2006 • 276 citations

Centrosome Maturation and Duplication in C. elegans Require the Coiled-Coil Protein SPD-2

2004 • 274 citations

Centriole cycle in Chinese hamster ovary cells as determined by whole-mount electron microscopy.

1981 • 271 citations

The Chromosome Cycle and the Centrosome Cycle in the Mitotic Cycle

1987 • 263 citations

The Caenorhabditis elegans Centrosomal Protein SPD-2 Is Required for both Pericentriolar Material Recruitment and Centriole Duplication

2004 • 241 citations

Polo-like Kinase 1 Regulates Nlp, a Centrosome Protein Involved in Microtubule Nucleation

2003 • 238 citations

The Centrosomal Protein C-Nap1 Is Required for Cell Cycle–Regulated Centrosome Cohesion

2000 • 232 citations

SAS-4 Is Essential for Centrosome Duplication in C. elegans and Is Recruited to Daughter Centrioles Once per Cell Cycle

2003 • 217 citations

Origins and consequences of centrosome aberrations in human cancers

2006 • 210 citations

De novo formation of centrosomes in vertebrate cells arrested during S phase

2002 • 204 citations

Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis

2005 • 202 citations

Sequential Protein Recruitment in C. elegans Centriole Formation

2006 • 202 citations

Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM

2004 • 192 citations

The de novo centriole assembly pathway in HeLa cells

2005 • 183 citations

Centrosome number is controlled by a centrosome-intrinsic block to reduplication

2003 • 183 citations

Microtubule nucleation

2003 • 173 citations

Protein 4.1 R-135 Interacts with a Novel Centrosomal Protein (CPAP) Which Is Associated with the γ-Tubulin Complex

2000 • 163 citations

Centriole number and the reproductive capacity of spindle poles.

1985 • 162 citations

Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells

2007 • 155 citations

Rootletin Interacts with C-Nap1 and May Function as a Physical Linker between the Pair of Centrioles/Basal Bodies in Cells

2005 • 155 citations

Controlling centrosome number: licenses and blocks

2005 • 155 citations

Late mitotic failure in mice lacking Sak, a polo-like kinase

2001 • 153 citations

The arithmetic of centrosome biogenesis

2004 • 150 citations

Cytoskeletal genes regulating brain size

2005 • 146 citations

Centrosome maturation

1999 • 145 citations

Bld10p, a novel protein essential for basal body assembly in Chlamydomonas

2004 • 143 citations

Kinetics and regulation of de novo centriole assembly

2001 • 133 citations

Reconstruction of the Centrosome Cycle from Cryoelectron Micrographs

1997 • 125 citations

The chromosome replication cycle

2002 • 124 citations

Centriole distribution during tripolar mitosis in Chinese hamster ovary cells.

1984 • 112 citations

Elucidation of Basal Body and Centriole Functions in Chlamydomonas reinhardtii

2003 • 111 citations

Basal Body Duplication and Maintenance Require One Member of theTetrahymena thermophilaCentrin Gene Family

2005 • 97 citations

Cell Biology of Normal and Abnormal Ciliogenesis in the Ciliated Epithelium

2004 • 91 citations

Centrosome-associated RNA in surf clam oocytes

2006 • 85 citations

Centrosomes in development and disease

2004 • 76 citations

Centrosomes in Development and Disease

2004 • 66 citations

Centrosome Duplication and Nematodes: Recent Insights from an Old Relationship

2005 • 56 citations

Mitotic Regulators Govern Progress through Steps in the Centrosome Duplication Cycle

1999 • 51 citations

Two-way traffic: centrosomes and the cell cycle

2005 • 48 citations

Are there nucleic acids in the centrosome?

1999 • 46 citations

Anomalous centriole configurations are detected inDrosophilawing disc cells upon Cdk1 inactivation

2002 • 46 citations

Independence of centriole formation and initiation of DNA synthesis in Chinese hamster ovary cells

1986 • 31 citations