Dendritic cell-based vaccines in the setting of peripheral blood stem cell transplantation: CD34+ cell-depleted mobilized peripheral blood can serve as a source of potent dendritic cells.

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

1996 • 1,854 citations

CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells.

1996 • 1,105 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.

1996 • 922 citations

DNA–based immunization by in vivo transfection of dendritic cells

1996 • 849 citations

Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic Cells

1996 • 770 citations

Dendritic Cells: Features and Functions

1980 • 585 citations

Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo.

1996 • 561 citations

Generation of Human Cytotoxic T Cells Specific for Human Carcinoembryonic Antigen Epitopes From Patients Immunized With Recombinant Vaccinia-CEA Vaccine

1995 • 506 citations

Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide.

1995 • 446 citations

Allogeneic cell therapy with donor peripheral blood cells and recombinant human interleukin-2 to treat leukemia relapse after allogeneic bone marrow transplantation

1996 • 439 citations

Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing.

1996 • 418 citations

Searching for hematopoietic stem cells: evidence that Thy-1.1lo Lin- Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow.

1992 • 368 citations

Dendritic cells are the principal stimulators of the primary mixed leukocyte reaction in mice

1983 • 367 citations

Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo

1994 • 300 citations

Dendritic cells as initiators of tumor immune responses: a possible strategy for tumor immunotherapy?

1995 • 264 citations

Separation of T and B Lymphocytes by Nylon Wool Columns: Evaluation of Efficacy by Functional Assays in Vivo

1974 • 218 citations

Selection and expansion of peripheral blood CD34+ cells in autologous stem cell transplantation for breast cancer

1996 • 184 citations

Generation of Dendritic Cells In Vitro From Peripheral Blood Mononuclear Cells With Granulocyte-Macrophage-Colony-Stimulating Factor, Interleukin-4, and Tumor Necrosis Factor-α for Use in Cancer Immunotherapy

1997 • 108 citations

Murine epidermal Langerhans cells and splenic dendritic cells present tumor‐associated antigens to primed T cells

1994 • 104 citations

Dendritic cells: a major story unfolds

1995 • 97 citations

Primitive hematopoietic cells in murine bone marrow express the CD34 antigen

1996 • 95 citations

Getting to the Source: Dendritic Cells as Therapeutic Reagents for the Treatment of Patients With Cancer

1997 • 95 citations

The Role of Tumor Necrosis Factor α in Modulating the Quantity of Peripheral Blood-Derived, Cytokine-Driven Human Dendritic Cells and Its Role in Enhancing the Quality of Dendritic Cell Function in Presenting Soluble Antigens to CD4+ T Cells In Vitro

1998 • 84 citations

Dendritic cells that process and present nominal antigens to naive T lymphocytes are derived from CD2+ precursors.

1997 • 67 citations

Restricted TCR repertoire and long-term persistence of donor-derived antigen-experienced CD4+ T cells in allogeneic bone marrow transplantation recipients.

1996 • 64 citations

Tumor antigen presentation by epidermal antigen-presenting cells in the mouse: modulation by granulocyte-macrophage colony-stimulating factor, tumor necrosis factor α, and ultraviolet radiation

1992 • 59 citations

Generation of Virtually Pure and Potentially Proliferating Dendritic Cells From Non-CD34 Apheresis Cells From Patients With Multiple Myeloma

1997 • 45 citations

CD4+ T-cells from mice immunized to syngeneic sarcomas recognize distinct, non-shared tumor antigens.

1994 • 44 citations

Active immunization of murine allogeneic bone marrow transplant donors with B-cell tumor-derived idiotype: a strategy for enhancing the specific antitumor effect of marrow grafts

1996 • 39 citations

Use of Interleukin-7, Interleukin-2, and Interferon-γ to Propagate CD4+ T Cells in Culture with Maintained Antigen Specificity

1993 • 22 citations

Peripheral blood stem cell transplantation.

1993 • 13 citations

Short-term ex vivo activation of splenocytes with anti-CD3 plus IL-2 and infusion post-BMT into mice results in in vivo expansion of effector cells with potent anti-lymphoma activity.

1994 • 10 citations