Human Papillomavirus Infection and TP53 Gene Mutation in Primary Cervical Carcinoma

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1990 • 3,896 citations

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.

1989 • 3,707 citations

Amplification of a gene encoding a p53-associated protein in human sarcomas

1992 • 1,959 citations

Tumor Suppressor Genes

1991 • 1,784 citations

Molecular themes in oncogenesis

1991 • 1,663 citations

Viruses in Human Cancers

1991 • 793 citations

Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group.

1990 • 515 citations

Clonal p53 mutation in primary cervical cancer: association with human-papillomavirus-negative tumours

1992 • 313 citations

A variation in the structure of the protein-coding region of the human p53 gene

1988 • 286 citations

The polymerase chain reaction: a new epidemiological tool for investigating cervical human papillomavirus infection.

1989 • 277 citations

Association between poor prognosis in early-stage invasive cervical carcinomas and non-detection of HPV DNA

1990 • 270 citations

Genetic analysis of human esophageal tumors from two high incidence geographic areas: frequent p53 base substitutions and absence of ras mutations.

1991 • 196 citations

Frequent allelic losses and mutations of the p53 gene in human ovarian cancer.

1991 • 194 citations

Alterations of the p53 gene in human primary cervical carcinoma with and without human papillomavirus infection.

1992 • 177 citations

Possible prognostic significance of human papillomavirus type in cervical cancer

1988 • 128 citations

Human papillomaviruses and cervical cancer: Analysis of histopathologic features associated with different viral types

1988 • 123 citations

Analysis of the p53 gene in human uterine carcinoma cell lines.

1991 • 105 citations

Presence and persistence of HPV infection and p53 mutation in cancer of the cervix uteri and the vulva

1995 • 92 citations

Mutations of p53 and human papillomavirus infection in cervical carcinoma

1993 • 91 citations

p53 mutations in HPV-negative cervical carcinoma.

1994 • 84 citations

Genetic alterations of the TP53 gene, p53 protein expression and hpv infection in primary cervical carcinomas

1993 • 74 citations

p53 mutations in cervical carcinogenesis – low frequency and lack of correlation with human papillomavirus status

1994 • 70 citations

p53 gene mutations and MDM2 amplification are uncommon in primary carcinomas of the uterine cervix.

1993 • 70 citations

Human Papillomavirus Types 16 and 18 in Adenocarcinoma of the Uterine Cervix

1991 • 49 citations

The role of p53 inactivation in human cervical cell carcinoma development

1995 • 38 citations

Chromosome 17p loss in carcinoma of the cervix uteri

1989 • 35 citations

Oligonucleotide primers for DNA amplification of the early regions 1, 6, and 7 from human papillomavirus types 6, 11, 16, 18, 31, and 33

1991 • 30 citations

p53 Mutation and MDM2 amplification are rare even in human papillomavirus-negative cervical carcinomas

1995 • 27 citations

Molecular diagnostics of human cancer. Cancer cells

1990 • 25 citations

Deleted Work

1955 • 0 citations