Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

1980 • 8,270 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 • 1,589 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma

1988 • 1,022 citations

A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16

1985 • 715 citations

Amplification and analysis of DNA sequences in single human sperm and diploid cells

1988 • 685 citations

Chromosome 5 allele loss in human colorectal carcinomas

1987 • 566 citations

Localization of cystic fibrosis locus to human chromosome 7cen–q22

1985 • 498 citations

A closely linked genetic marker for cystic fibrosis

1985 • 463 citations

Detection of single base substitutions in total genomic DNA

1985 • 375 citations

A polymorphic DNA marker linked to cystic fibrosis is located on chromosome 7

1985 • 332 citations

An estimate of unique DNA sequence heterozygosity in the human genome

1985 • 297 citations

Deletion of genes on chromosome 1 in endocrine neoplasia

1987 • 265 citations

Genetics of cancer predisposition.

1987 • 199 citations

Isolation and regional localization of DNA segments revealing polymorphic loci from human chromosome 13.

1984 • 171 citations

Mutation Affecting the 12th Amino Acid of the c-Ha- ras Oncogene Product Occurs Infrequently in Human Cancer

1983 • 162 citations

Concerted Nonsyntenic Allelic Loss in Human Colorectal Carcinoma

1988 • 147 citations

Molecular cloning and the total nucleotide sequence of the human c-Ha-ras-1 gene activated in a melanoma from a Japanese patient.

1984 • 131 citations

Report of the committee on the genetic constitution of chromosomes 13, 14, 15 and 16

1987 • 57 citations

Loss of genes on the short arm of chromosome 11 in human lung carcinomas.

1987 • 57 citations

Detection of human DNA polymorphisms with a simplified denaturing gradient gel electrophoresis technique.

1987 • 42 citations

Growth, morphology, and function of xenotransplanted human tumors.

1979 • 32 citations

The molecular genetics of Duchenne muscular dystrophy: the beginning of the end?

1988 • 17 citations

[60] Analysis of Escherichia coli mutants of the H+-transporting ATPase: Determination of altered site of the structural genes

1986 • 16 citations

Amplification of activated c-Ha-ras-1 in human melanoma.

1985 • 15 citations

Essential region for transforming activity of human c-Ha-ras-1.

1985 • 3 citations