Status of Activation of Circulating Vaccine-Elicited CD8+ T Cells

Real time quantitative PCR.

1996 • 6,155 citations

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Phenotypic Analysis of Antigen-Specific T Lymphocytes

1996 • 3,611 citations

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

1998 • 1,826 citations

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

1998 • 1,426 citations

Escape of Human Solid Tumors from T–Cell Recognition: Molecular Mechanisms and Functional Significance

1999 • 1,168 citations

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

1999 • 1,131 citations

Phototyping: comprehensive DNA typing for HLA‐A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing sequence‐specific primers (PCR‐SSP)

1995 • 1,018 citations

Direct Visualization of Antigen-specific CD8+T Cells during the Primary Immune Response to Epstein-Barr Virus In Vivo

1998 • 902 citations

Ex Vivo Staining of Metastatic Lymph Nodes by Class I Major Histocompatibility Complex Tetramers Reveals High Numbers of Antigen-experienced Tumor-specific Cytolytic T Lymphocytes

1998 • 534 citations

A Re-Evaluation of the Frequency of CD8+ T Cells Specific for EBV in Healthy Virus Carriers

1999 • 520 citations

A Kinetic Basis For T Cell Receptor Repertoire Selection during an Immune Response

1999 • 515 citations

High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

1999 • 497 citations

High Frequency of Skin-homing Melanocyte-specific Cytotoxic T Lymphocytes in Autoimmune Vitiligo

1998 • 446 citations

Isolation of High Avidity Melanoma-Reactive CTL from Heterogeneous Populations Using Peptide-MHC Tetramers

1999 • 423 citations

From TCR Engagement to T Cell Activation

1999 • 379 citations

T-cell epitope mapping by flow cytometry

1998 • 295 citations

Increased Vaccine-Specific T Cell Frequency After Peptide-Based Vaccination Correlates with Increased Susceptibility to In Vitro Stimulation But Does Not Lead to Tumor Regression

1999 • 290 citations

Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction.

1996 • 290 citations

Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A.

1997 • 286 citations

Analysis of Gag-specific Cytotoxic T Lymphocytes in Simian Immunodeficiency Virus–infected Rhesus Monkeys by Cell Staining with a Tetrameric Major Histocompatibility Complex Class I–Peptide Complex

1998 • 281 citations

Frequency of Class I HLA-Restricted Anti-HIV CD8+ T Cells in Individuals Receiving Highly Active Antiretroviral Therapy (HAART)

1999 • 274 citations

Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL.

1996 • 222 citations

Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors.

1996 • 208 citations

Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear Cells and Tumor Specimens

1999 • 206 citations

Specificity of CTL Interactions with Peptide-MHC Class I Tetrameric Complexes Is Temperature Dependent

1999 • 197 citations

Quantification of cytokine mRNA expression by RT PCR in samples of previously frozen blood

1997 • 169 citations

Quantitative correlation between HLA class I allele expression and recognition of melanoma cells by antigen-specific cytotoxic T lymphocytes.

1995 • 166 citations

Direct Analysis of Viral-Specific CD8+ T Cells with Soluble HLA-A2/Tax11-19 Tetramer Complexes in Patients with Human T Cell Lymphotropic Virus-Associated Myelopathy

1999 • 136 citations

Suboptimal activation of melanoma infiltrating lymphocytes (TIL) due to low avidity of TCR/MHC-tumor peptide interactions.

1996 • 128 citations

Functional Dissociation Between Local and Systemic Immune Response During Anti-Melanoma Peptide Vaccination

1998 • 127 citations

Differential Anti-MART-1/MelanA CTL Activity in Peripheral Blood of HLA-A2 Melanoma Patients in Comparison to Healthy Donors

1996 • 127 citations

The Use of HLA A2.1/p53 Peptide Tetramers to Visualize the Impact of Self Tolerance on the TCR Repertoire

2000 • 110 citations

Selective Histocompatibility Leukocyte Antigen (Hla)-A2 Loss Caused by Aberrant Pre-mRNA Splicing in 624mel28 Melanoma Cells

1999 • 104 citations

Selecting T Cell Receptors with High Affinity for Self-MHC by Decreasing the Contribution of CD8

1992 • 98 citations

Expansion of Tumor-T Cell Pairs from Fine Needle Aspirates of Melanoma Metastases

2000 • 76 citations

Circulating MELAN-A/MART-1 specific cytolytic T lymphocyte precursors in HLA-A2+ melanoma patients have a memory phenotype

1998 • 67 citations

Selective reconstitution of CD8+ cytotoxic T lymphocyte responses in immunodeficient bone marrow transplant recipients by the adoptive transfer of T cell clones.

1994 • 59 citations

The Avidity Spectrum of T Cell Receptor Interactions Accounts for T Cell Anergy in a Double Transgenic Model

1999 • 51 citations

Differences in Frequency Distribution of HLA-A2 Subtypes Between North American and Italian White Melanoma Patients: Relevance for Epitope Specific Vaccination Protocols

1996 • 45 citations

Activation or frustration of anti-tumor responses by T-cell-based immune modulation

1997 • 15 citations