Cellular mechanisms of netrin function: Long-range and short-range actions

The Molecular Biology of Axon Guidance

1996 • 3,246 citations

Histologie du système nerveux de l'homme & des vertébrés

1909 • 2,282 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

1994 • 1,346 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System

1996 • 1,253 citations

Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor

1996 • 982 citations

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

1990 • 909 citations

Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene

1997 • 764 citations

RETRACTED: A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion

1999 • 686 citations

Chemotropic guidance of developing axons in the mammalian central nervous system

1988 • 681 citations

The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

1995 • 566 citations

La rétine des vertébrés

1892 • 559 citations

cAMP-Dependent Growth Cone Guidance by Netrin-1

1997 • 550 citations

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

1997 • 511 citations

UNC-40, a C. elegans Homolog of DCC (Deleted in Colorectal Cancer), Is Required in Motile Cells Responding to UNC-6 Netrin Cues

1996 • 491 citations

Biochemical Purification of a Mammalian Slit Protein as a Positive Regulator of Sensory Axon Elongation and Branching

1999 • 464 citations

Genetic Analysis of Netrin Genes in Drosophila: Netrins Guide CNS Commissural Axons and Peripheral Motor Axons

1996 • 459 citations

frazzled Encodes a Drosophila Member of the DCC Immunoglobulin Subfamily and Is Required for CNS and Motor Axon Guidance

1996 • 456 citations

Netrin-1 and DCC Mediate Axon Guidance Locally at the Optic Disc: Loss of Function Leads to Optic Nerve Hypoplasia

1997 • 434 citations

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

1992 • 404 citations

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein

1997 • 372 citations

Neuroglia and Pioneer Neurons Express UNC-6 to Provide Global and Local Netrin Cues for Guiding Migrations in C. elegans

1996 • 359 citations

Capturing genes encoding membrane and secreted proteins important for mouse development.

1995 • 321 citations

Phospholipase C-γ and Phosphoinositide 3-Kinase Mediate Cytoplasmic Signaling in Nerve Growth Cone Guidance

1999 • 281 citations

Turning of Retinal Growth Cones in a Netrin-1 Gradient Mediated by the Netrin Receptor DCC

1997 • 280 citations

Genetic Analysis of the Mechanisms Controlling Target Selection: Complementary and Combinatorial Functions of Netrins, Semaphorins, and IgCAMs

1998 • 256 citations

Genes necessary for directed axonal elongation or fasciculation in C. elegans

1992 • 245 citations

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally

1993 • 237 citations

Motor Axon Subpopulations Respond Differentially to the Chemorepellents Netrin-1 and Semaphorin D

1997 • 237 citations

Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant

1990 • 227 citations

A GTPase Controlling Nuclear Trafficking: Running the Right Way or Walking RANdomly?

1996 • 211 citations

The DCC gene product in cellular differentiation and colorectal tumorigenesis.

1994 • 189 citations

Netrin and Netrin Receptor Expression in the Embryonic Mammalian Nervous System Suggests Roles in Retinal, Striatal, Nigral, and Cerebellar Development

1997 • 184 citations

The NTR module: Domains of netrins, secreted frizzled related proteins, and type I procollagen C‐proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases

1999 • 180 citations

Suppressors of Ectopic UNC-5 Growth Cone Steering Identify Eight Genes Involved in Axon Guidance inCaenorhabditis elegans

1998 • 175 citations

Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancer.

1994 • 157 citations

Guidance of Circumferentially Growing Axons by Netrin-Dependent and -Independent Floor Plate Chemotropism in the Vertebrate Brain

1996 • 122 citations

Multiple Factors Govern Intraretinal Axon Guidance: A Time-Lapse Study

1995 • 98 citations

Expression and alternative splicing of the deleted in colorectal cancer (DCC) gene in normal and malignant tissues.

1994 • 98 citations

Identification and expression of mouse netrin-4

2000 • 98 citations

Unique Changes of Ganglion Cell Growth Cone Behavior Following Cell Adhesion Molecule Perturbations: A Time-Lapse Study of the Living Retina

1995 • 97 citations

Axon Tracts Correlate withNetrin-1aExpression in the Zebrafish Embryo

1997 • 95 citations

Expression and regulation of a netrin homologue in the zebrafish embryo

1997 • 95 citations

Mouse Neogenin, a DCC-like molecule, has four splice variants and is expressed widely in the adult mouse and during embryogenesis

1997 • 93 citations

Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas.

1999 • 90 citations

Identification and characterization of neogenin, a DCC-related gene

1997 • 85 citations

DCC: linking tumor suppressor genes and altered cell surface interactions in cancer?

1995 • 85 citations

Chapter 11 Semaphorin-mediated neuronal growth cone guidance

1998 • 80 citations

Loss of DCC expression and glioma progression.

1997 • 70 citations

Glycosaminoglycan-Binding Properties and Secondary Structure of the C-Terminus of Netrin-1

2000 • 66 citations

Axon growth in embryonic chick and quail retinal whole mounts in vitro

1984 • 65 citations

TheNTN2LGene Encoding a Novel Human Netrin Maps to the Autosomal Dominant Polycystic Kidney Disease Region on Chromosome 16p13.3

1997 • 54 citations

DCC expression is altered by multiple mechanisms in brain tumours.

1995 • 48 citations

Homozygous deletions inactivateDCC, but notMADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers

2000 • 45 citations

Distal Recognition Site for Classical Pathway Convertase Located in the C345C/Netrin Module of Complement Component C5

2000 • 35 citations

The Spatial and Temporal Expression Patterns of Netrin Receptors, DCC and Neogenin, in the Developing Mouse Retina

2000 • 32 citations

Adhesive Interactions That Regulate Development of the Retina and Primary Visual Projection

1992 • 15 citations