Turning of Retinal Growth Cones in a Netrin-1 Gradient Mediated by the Netrin Receptor DCC

Normal Table of Xenopus Laevis (Daudin)

1958 • 4,561 citations

The Molecular Biology of Axon Guidance

1996 • 3,246 citations

Normal table of Xenopus laevis (Daudin)

1995 • 2,955 citations

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

1994 • 1,346 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System

1996 • 1,253 citations

Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor

1996 • 982 citations

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

1990 • 909 citations

Induction of epidermis and inhibition of neural fate by Bmp-4

1995 • 782 citations

Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene

1997 • 764 citations

Chemotropic guidance of developing axons in the mammalian central nervous system

1988 • 681 citations

cAMP-induced switching in turning direction of nerve growth cones

1997 • 614 citations

Turning of nerve growth cones induced by neurotransmitters

1994 • 583 citations

The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

1995 • 566 citations

La rétine des vertébrés

1892 • 559 citations

Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth Factor

1979 • 522 citations

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

1997 • 511 citations

UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans

1992 • 503 citations

UNC-40, a C. elegans Homolog of DCC (Deleted in Colorectal Cancer), Is Required in Motile Cells Responding to UNC-6 Netrin Cues

1996 • 491 citations

Inhibition of activin receptor signaling promotes neuralization in Xenopus

1994 • 484 citations

Genetic Analysis of Netrin Genes in Drosophila: Netrins Guide CNS Commissural Axons and Peripheral Motor Axons

1996 • 459 citations

frazzled Encodes a Drosophila Member of the DCC Immunoglobulin Subfamily and Is Required for CNS and Motor Axon Guidance

1996 • 456 citations

Netrin-1 and DCC Mediate Axon Guidance Locally at the Optic Disc: Loss of Function Leads to Optic Nerve Hypoplasia

1997 • 434 citations

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

1992 • 404 citations

Guidance of optic axons in vivo by a preformed adhesive pathway on neuroepithelial endfeet

1984 • 386 citations

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein

1997 • 372 citations

Neuroglia and Pioneer Neurons Express UNC-6 to Provide Global and Local Netrin Cues for Guiding Migrations in C. elegans

1996 • 359 citations

Asymmetric modulation of cytosolic cAMP activity induces growth cone turning

1992 • 355 citations

Localization of specific mRNAs in Xenopus embryos by whole-mount in situ hybridization

1990 • 323 citations

A mechanism for the guidance and topographic patterning of retinal ganglion cell axons

1980 • 322 citations

Guidance Cues at the Drosophila CNS Midline: Identification and Characterization of Two Drosophila Netrin/UNC-6 Homologs

1996 • 322 citations

Properties and functions of the surface coat in amphibian embryos

1943 • 320 citations

Navigational errors made by growth cones without filopodia in the embryonic xenopus brain

1993 • 264 citations

Genes necessary for directed axonal elongation or fasciculation in C. elegans

1992 • 245 citations

Motor Axon Subpopulations Respond Differentially to the Chemorepellents Netrin-1 and Semaphorin D

1997 • 237 citations

Axonal guidance during development of the optic nerve: The role of pigmented epithelia and other extrinsic factors

1981 • 233 citations

Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant

1990 • 227 citations

Guidance of commissural growth cones at the floor plate in embryonic rat spinal cord

1990 • 210 citations

A role for netrin-1 in the guidance of cortical efferents

1997 • 202 citations

The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain

1997 • 193 citations

Netrin and Netrin Receptor Expression in the Embryonic Mammalian Nervous System Suggests Roles in Retinal, Striatal, Nigral, and Cerebellar Development

1997 • 184 citations

A single-cell analysis of early retinal ganglion cell differentiation in Xenopus: from soma to axon tip

1989 • 179 citations

FGF signaling and target recognition in the developing xenopus visual system

1995 • 168 citations

Directed Growth of Early Cortical Axons Is Influenced by a Chemoattractant Released from an Intermediate Target

1997 • 160 citations

Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancer.

1994 • 157 citations

Oriented extracellular channels and axonal guidance in the embryonic chick retina

1981 • 156 citations

Guidance of Circumferentially Growing Axons by Netrin-Dependent and -Independent Floor Plate Chemotropism in the Vertebrate Brain

1996 • 122 citations

Two cellular inductions involved in photoreceptor determination in the Xenopus retina

1992 • 119 citations

Growth Cone Form Is Behavior-Specific and, Consequently, Position-Specific along the Retinal Axon Pathway

1997 • 119 citations

Rapid effects of laminin on the growth cone

1992 • 104 citations

Multiple Factors Govern Intraretinal Axon Guidance: A Time-Lapse Study

1995 • 98 citations

Unique Changes of Ganglion Cell Growth Cone Behavior Following Cell Adhesion Molecule Perturbations: A Time-Lapse Study of the Living Retina

1995 • 97 citations

Growth cones of developing retinal cells in vivo, on culture surfaces, and in collagen matrices

1985 • 96 citations

Axon Tracts Correlate withNetrin-1aExpression in the Zebrafish Embryo

1997 • 95 citations

Expression and regulation of a netrin homologue in the zebrafish embryo

1997 • 95 citations

Sensory neurite growth cone guidance by substrate adsorbed nerve growth factor

1985 • 91 citations

Guidance of Developing Axons by Diffusible Chemoattractants

1990 • 80 citations

Development and characterization of commissural interneurones in the spinal cord of Xenopus laevis embryos revealed by antibodies to glycine

1988 • 73 citations

Precocious pathfinding: Retinal axons can navigate in an axonless brain

1992 • 70 citations

Chemosuppression of Retinal Axon Growth by the Mouse Optic Chiasm

1996 • 69 citations

Axon growth in embryonic chick and quail retinal whole mounts in vitro

1984 • 65 citations

TheNTN2LGene Encoding a Novel Human Netrin Maps to the Autosomal Dominant Polycystic Kidney Disease Region on Chromosome 16p13.3

1997 • 54 citations

Immunohistochemical Localization of Netrin-1 in the Embryonic Chick Nervous System

1997 • 49 citations

Expression of a Homologue of the Deleted in Colorectal Cancer (DCC) Gene in the Nervous System of Developing Xenopus Embryos

1994 • 40 citations

The early development of the frog retinotectal projection.

1991 • 33 citations

Intraretinal Grafting Reveals Growth Requirements and Guidance Cues for Optic Axons in the Developing Avian Retina

1996 • 23 citations

The early development of the frog retinotectal projection

1991 • 19 citations