Cellular accumulation of p53 protein: an independent prognostic factor in stage II breast cancer

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Regression Models and Life-Tables

1992 • 27,454 citations

Regression Models and Life-Tables

1972 • 27,145 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

A Detergent‐trypsin method for the preparation of nuclei for flow cytometric DNA analysis

1983 • 1,681 citations

Statistical Methods in Medical Research.

1988 • 1,431 citations

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1990 • 1,045 citations

p53: oncogene or anti-oncogene?

1990 • 812 citations

Association of p53 Protein Expression With Tumor Cell Proliferation Rate and Clinical Outcome in Node-Negative Breast Cancer

1993 • 777 citations

Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

1992 • 757 citations

P53 expression in breast cancer

1988 • 612 citations

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion.

1992 • 587 citations

Association of Overexpression of Tumor Suppressor Protien p53 With Rapid Cell Proliferation and Poor Prognosis in Node-Negative Breast Cancer Patients

1992 • 349 citations

How To Use Prognostic Factors in Axillary Node-Negative Breast Cancer Patients

1990 • 323 citations

Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro

1990 • 283 citations

Prognostic significance of cytoplasmic p53 oncoprotein in colorectal adenocarcinoma

1992 • 233 citations

Improving the prognostic value of DNA flow cytometry in breast cancer by combining DNA index and S-phase fraction: A proposed classification of DNA histograms in breast cancer

1988 • 226 citations

Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport

1991 • 180 citations

Increased p53 protein content of colorectal tumours correlates with poor survival

1992 • 147 citations

Cytosol estradiol receptor in human mammary carcinoma: An assay based on isoelectric focusing in polyacrylamide gel

1978 • 143 citations

Breast cancer genetic evolution: I. Data from cytogenetics and DNA content

1991 • 142 citations

Nuclear p53 protein accumulates preferentially in medullary and high-grade ductal but rarely in lobular breast carcinomas.

1993 • 76 citations

Immunohistochemical analysis of p53 and HER-2/neu proteins in human tumors.

1991 • 63 citations

Correlation between the conformational phenotype of p53 and its subcellular location.

1992 • 54 citations

Inhibition of DNA synthesis by TGF-β1 coincides with inhibition of phosphorylation and cytoplasmic translocation of p53 protein

1992 • 30 citations

Relationships of DNA ploidy, S‐phase fraction and hormone receptor status to tumor stage in breast cancers detected by population screening

1992 • 26 citations