Reduced IFNγ production in response to IL‐12 stimulation and/or reduced IL‐12 production in atopic patients

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers.

1991 • 976 citations

IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses.

1988 • 731 citations

A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma.

1986 • 727 citations

IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants.

1988 • 713 citations

Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production.

1990 • 353 citations

Atopic Dermatitis: Recent Trends in Pathogenesis and Therapy

1994 • 349 citations

IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma.

1988 • 315 citations

Mechanisms of IFN-gamma induction by natural killer cell stimulatory factor (NKSF/IL-12). Role of transcription and mRNA stability in the synergistic interaction between NKSF and IL-2.

1992 • 284 citations

Decreased interferon gamma and increased interleukin-4 production in atopic dermatitis promotes IgE synthesis

1992 • 277 citations

Age-related serum immunoglobulin E levels in healthy subjects and in patients with allergic disease

1980 • 269 citations

IL-4 inhibits the synthesis of IFN-gamma and induces the synthesis of IgE in human mixed lymphocyte cultures.

1990 • 262 citations

Shifts in interleukin-4 and interferon-γ production by T cells of patients with elevated serum IgE levels and the modulatory effects of these lymphokines on spontaneous IgE synthesis

1991 • 224 citations

CD40 stimulation provides an IFN-gamma-independent and IL-4-dependent differentiation signal directly to human B cells for IgE production.

1991 • 219 citations

IL-4 and interferon-gamma production in children with atopic disease

1993 • 168 citations

Human Eosinophils Produce Biologically Active IL-12: Implications for Control of T Cell Responses

1998 • 119 citations

Interleukin‐4 and interferon‐gamma production in atopic and non‐atopic children with ashma

1995 • 116 citations

Kinetics of cell infiltration and cytokine messenger RNA expression after intradermal challenge with allergen and tuberculin in the same atopic individuals

1994 • 93 citations

IL-18 and CD28 use distinct molecular mechanisms to enhance NK cell production of IL-12-induced IFN-gamma.

1999 • 89 citations

IL-18 and CD28 Use Distinct Molecular Mechanisms to Enhance NK Cell Production of IL-12-Induced IFN-γ

1999 • 70 citations

Interferon-γ–Dependent Inducible Expression of the Human Interleukin-12 p35 Gene in Monocytes Initiates From a TATA-Containing Promoter Distinct From the CpG-Rich Promoter Active in Epstein-Barr Virus-Transformed Lymphoblastoid Cells

1998 • 62 citations

Reduced interferon-γ but normal IL-4 and IL-5 release by peripheral blood mononuclear cells from Xhosa children with atopic asthma

1997 • 48 citations

Interferon-γ–Dependent Inducible Expression of the Human Interleukin-12 p35 Gene in Monocytes Initiates From a TATA-Containing Promoter Distinct From the CpG-Rich Promoter Active in Epstein-Barr Virus-Transformed Lymphoblastoid Cells

1998 • 45 citations

Serum IgE level is negatively correlated with the ability of peripheral mononuclear cells to produce interferon gamma (IFNγ): evidence of reduced expression of IFNγ mRNA in atopic patients

1998 • 45 citations