Virus Entry, Assembly, Budding, and Membrane Rafts

Functional rafts in cell membranes

1997 • 9,471 citations

The Fluid Mosaic Model of the Structure of Cell Membranes

1972 • 8,835 citations

Lipid rafts and signal transduction

2000 • 6,079 citations

Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts

2000 • 2,321 citations

Lipid Rafts Reconstituted in Model Membranes

2001 • 1,330 citations

GPI-anchored proteins are organized in submicron domains at the cell surface

1998 • 1,207 citations

Sphingolipid–Cholesterol Rafts Diffuse as Small Entities in the Plasma Membrane of Mammalian Cells

2000 • 987 citations

Cholesterol, lipid rafts, and disease

2002 • 985 citations

Structure and Origin of Ordered Lipid Domains in Biological Membranes

1998 • 962 citations

Cholesterol, lipid rafts, and disease

2002 • 841 citations

Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor

1999 • 800 citations

Caveolae, DIGs, and the dynamics of sphingolipid—cholesterol microdomains

1997 • 783 citations

Evidence for Budding of Human Immunodeficiency Virus Type 1 Selectively from Glycolipid-Enriched Membrane Lipid Rafts

2000 • 768 citations

Plasma membrane rafts play a critical role in HIV-1 assembly and release

2001 • 675 citations

Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain

1997 • 644 citations

Role of Lipid Modifications in Targeting Proteins to Detergent-resistant Membrane Rafts

1999 • 626 citations

Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import

1991 • 559 citations

Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane

2000 • 557 citations

Cholesterol Is Required for Surface Transport of Influenza Virus Hemagglutinin

1998 • 555 citations

Microdomains of GPI-anchored proteins in living cells revealed by crosslinking

1998 • 555 citations

Influenza Viruses Select Ordered Lipid Domains during Budding from the Plasma Membrane

1999 • 445 citations

Lipid Raft Microdomains

2002 • 438 citations

Lipid composition and fluidity of the human immunodeficiency virus envelope and host cell plasma membranes.

1993 • 424 citations

Viral Late Domains

2002 • 418 citations

Endocytosis without clathrin coats

2001 • 418 citations

Looking at lipid rafts?

1999 • 406 citations

Influenza Virus Assembly and Lipid Raft Microdomains: a Role for the Cytoplasmic Tails of the Spike Glycoproteins

2000 • 377 citations

Functionally different GPI proteins are organized in different domains on the neuronal surface

1999 • 363 citations

Virus Maturation by Budding

1998 • 359 citations

Membrane raft microdomains mediate lateral assemblies required for HIV‐1 infection

2000 • 352 citations

Lipid Rafts and HIV Pathogenesis: Host Membrane Cholesterol Is Required for Infection by HIV Type 1

2001 • 348 citations

pH-dependent fusion between the Semliki Forest virus membrane and liposomes.

1980 • 344 citations

Decay-accelerating factor (CD55), a glycosylphosphatidylinositol-anchored complement regulatory protein, is a receptor for several echoviruses.

1994 • 337 citations

HIV-1 Auxiliary Proteins: Making Connections in a Dying Cell

1998 • 328 citations

Human Immunodeficiency Virus Type 1 Uses Lipid Raft-Colocalized CD4 and Chemokine Receptors for Productive Entry into CD4 ⁺ T Cells

2002 • 313 citations

Flotillin-1-enriched Lipid Raft Domains Accumulate on Maturing Phagosomes

2001 • 305 citations

Lipid rafts and HIV-1: from viral entry to assembly of progeny virions

2001 • 273 citations

Human Immunodeficiency Virus Type 1 Enters Brain Microvascular Endothelia by Macropinocytosis Dependent on Lipid Rafts and the Mitogen-Activated Protein Kinase Signaling Pathway

2002 • 270 citations

The Nef protein of HIV-1 associates with rafts and primes T cells for activation

2000 • 269 citations

Raft membrane domains: from a liquid-ordered membrane phase to a site of pathogen attack

2001 • 262 citations

Influenza Virus Assembly: Effect of Influenza Virus Glycoproteins on the Membrane Association of M1 Protein

2000 • 257 citations

The role of lipid rafts in signalling and membrane trafficking in T lymphocytes

2001 • 252 citations

Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor.

1993 • 242 citations

Major histocompatibility complex class I molecules mediate association of SV40 with caveolae.

1997 • 242 citations

Vesicular stomatitis virus infects and matures only through the basolateral surface of the polarized epithelial cell line, MDCK

1984 • 236 citations

Implications of lipid microdomains for membrane curvature, budding and fission

2001 • 233 citations

Measles Virus Structural Components Are Enriched into Lipid Raft Microdomains: a Potential Cellular Location for Virus Assembly

2000 • 223 citations

Internalization of Echovirus 1 in Caveolae

2002 • 220 citations

Proteins related to the Nedd4 family of ubiquitin protein ligases interact with the L domain of Rous sarcoma virus and are required for gag budding from cells

2001 • 219 citations

Microvesicles Are a Source of Contaminating Cellular Proteins Found in Purified HIV-1 Preparations

1997 • 210 citations

Caveolar Endocytosis of Simian Virus 40 Is Followed by Brefeldin A-Sensitive Transport to the Endoplasmic Reticulum, Where the Virus Disassembles

2002 • 195 citations

Role of cholesterol in fusion of Semliki Forest virus with membranes

1984 • 192 citations

Constitutive cell surface association between CD4 and CCR5

1999 • 179 citations

Palmitoylation of the HIV-1 envelope glycoprotein is critical for viral infectivity

2000 • 179 citations

Membrane fusion of Semliki Forest virus in a model system: correlation between fusion kinetics and structural changes in the envelope glycoprotein.

1993 • 176 citations

Role for Human Immunodeficiency Virus Type 1 Membrane Cholesterol in Viral Internalization

2002 • 166 citations

The Cholesterol Requirement for Sindbis Virus Entry and Exit and Characterization of a Spike Protein Region Involved in Cholesterol Dependence

1999 • 165 citations

HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication

2002 • 165 citations

Lipid Rafts and Pseudotyping

2001 • 164 citations

Cholesterol is required for infection by Semliki Forest virus.

1991 • 164 citations

Evidence for a Stable Interaction of gp41 with Pr55^Gagin Immature Human Immunodeficiency Virus Type 1 Particles

2000 • 164 citations

Heat Shock Cognate Protein 70 Is Involved in Rotavirus Cell Entry

2002 • 162 citations

Role of Cholesterol in Human Immunodeficiency Virus Type 1 Envelope Protein-Mediated Fusion with Host Cells

2002 • 160 citations

Measles Virus Assembly within Membrane Rafts

2000 • 159 citations

The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells

1994 • 156 citations

Low-pH-Dependent Fusion of Sindbis Virus with Receptor-Free Cholesterol- and Sphingolipid-Containing Liposomes

1999 • 154 citations

Nef increases infectivity of HIV via lipid rafts

2001 • 150 citations

Cell Membrane Vesicles Are a Major Contaminant of Gradient-Enriched Human Immunodeficiency Virus Type-1 Preparations

1997 • 149 citations

Glycosphingolipids Promote Entry of a Broad Range of Human Immunodeficiency Virus Type 1 Isolates into Cell Lines Expressing CD4, CXCR4, and/or CCR5

2000 • 147 citations

Extensive temporally regulated reorganization of the lipid raft proteome following T-cell antigen receptor triggering

2003 • 144 citations

Association of the Caveola Vesicular System with Cellular Entry by Filoviruses

2002 • 142 citations

Specific Interaction of HIV-1 and HIV-2 Surface Envelope Glycoproteins with Monolayers of Galactosylceramide and Ganglioside GM3

1998 • 141 citations

A Single Point Mutation Controls the Cholesterol Dependence of Semliki Forest Virus Entry and Exit

1998 • 138 citations

Involvement of actin filaments in budding of measles virus: Studies on cytoskeletons of infected cells

1986 • 137 citations

A Novel Cell Entry Pathway for a DAF-Using Human Enterovirus Is Dependent on Lipid Rafts

2002 • 135 citations

Analysis of the Transmembrane Domain of Influenza Virus Neuraminidase, a Type II Transmembrane Glycoprotein, for Apical Sorting and Raft Association

2000 • 133 citations

Segregation of CD4 and CXCR4 into Distinct Lipid Microdomains in T Lymphocytes Suggests a Mechanism for Membrane Destabilization by Human Immunodeficiency Virus

2002 • 132 citations

The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55)

1996 • 127 citations

The HIV-1 assembly machine

2001 • 125 citations

Sphingomyelin and Cholesterol Promote HIV-1 gp41 Pretransmembrane Sequence Surface Aggregation and Membrane Restructuring

2002 • 123 citations

The Fusion Peptide of Semliki Forest Virus Associates with Sterol-Rich Membrane Domains

2002 • 122 citations

Polyploid measles virus with hexameric genome length

2002 • 120 citations

Chimeric Measles Viruses with a Foreign Envelope

1998 • 119 citations

Virion Incorporation of Human Immunodeficiency Virus Type 1 Nef Is Mediated by a Bipartite Membrane-Targeting Signal: Analysis of Its Role in Enhancement of Viral Infectivity

1998 • 119 citations

Synthetic Soluble Analogs of Galactosylceramide (GalCer) Bind to the V3 Domain of HIV-1 gp120 and Inhibit HIV-1-induced Fusion and Entry

1997 • 117 citations

Myristoylation as a target for inhibiting HIV assembly: Unsaturated fatty acids block viral budding

2002 • 116 citations

Differential solubilization of lipids along with membrane proteins by different classes of detergents

1995 • 116 citations

Assembly of Sendai Virus: M Protein Interacts with F and HN Proteins and with the Cytoplasmic Tail and Transmembrane Domain of F Protein

2000 • 115 citations

Functional involvement of a novel Nedd4‐like ubiquitin ligase on retrovirus budding

2002 • 112 citations

Noncovalent associations of T lymphocyte surface proteins

1996 • 111 citations

Biochemical Characterization of Rotavirus Receptors in MA104 Cells

2000 • 111 citations

Measles Virus Envelope Glycoproteins Hetero-oligomerize in the Endoplasmic Reticulum

2001 • 109 citations

HIV-1 gp41 Envelope Residues 650–685 Exposed on Native Virus Act as a Lectin to Bind Epithelial Cell Galactosyl Ceramide

2002 • 109 citations

Human Immunodeficiency Virus Type 1 Particles Pseudotyped with Envelope Proteins That Fuse at Low pH No Longer Require Nef for Optimal Infectivity

2001 • 104 citations

Extracellular Simian Virus 40 Transmits a Signal That Promotes Virus Enclosure within Caveolae

1999 • 100 citations

Blocking of HIV-1 Infection by Targeting CD4 to Nonraft Membrane Domains

2002 • 99 citations

Sorting of the Respiratory Syncytial Virus Matrix Protein into Detergent-Resistant Structures Is Dependent on Cell-Surface Expression of the Glycoproteins

2002 • 95 citations

Respiratory syncytial virus assembly occurs in GM1-rich regions of the host-cell membrane and alters the cellular distribution of tyrosine phosphorylated caveolin-1

2002 • 94 citations

Palmitoylation of the influenza a virus M2 protein

1990 • 86 citations

Caveolin-1 is incorporated into mature respiratory syncytial virus particles during virus assembly on the surface of virus-infected cells

2002 • 86 citations

Phorbol Ester-induced Disruption of the CD4-Lck Complex Occurs within a Detergent-resistant Microdomain of the Plasma Membrane

1999 • 85 citations

Sphingolipid and Cholesterol Dependence of Alphavirus Membrane Fusion

2002 • 84 citations

Human immunodeficiency virus and host cell lipids. Interesting pathways in research for a new HIV therapy

2002 • 84 citations

Expression of the influenza A virus M2 protein is restricted to apical surfaces of polarized epithelial cells

1992 • 79 citations

Rafts Promote Assembly and Atypical Targeting of a Nonenveloped Virus, Rotavirus, in Caco-2 Cells

2002 • 79 citations

Anchorage of HIV on Permissive Cells Leads to Coaggregation of Viral Particles with Surface Nucleolin at Membrane Raft Microdomains

2002 • 77 citations

MHC class I molecules are enriched in caveolae but do not enter with simian virus 40.

1998 • 74 citations

Budding of Rous sarcoma virus and vesicular stomatitis virus from localized lipid regions in the plasma membrane of chicken embryo fibroblasts.

1980 • 74 citations

HIV surveillance among injecting drug users

2001 • 72 citations

Effect of Influenza Virus Matrix Protein and Viral RNA on Ribonucleoprotein Formation and Nuclear Export

2001 • 68 citations

Ecotropic Murine Leukemia Virus Receptor Is Physically Associated with Caveolin and Membrane Rafts

2000 • 66 citations

Decay Accelerating Factor (CD55)

1992 • 66 citations

Exploitation of major histocompatibility complex class I molecules and caveolae by simian virus 40

1999 • 64 citations

Formation of membrane domains created during the budding of vesicular stomatitis virus. A model for selective lipid and protein sorting in biological membranes

1995 • 63 citations

Single molecule microscopy of biomembranes (Review)

2000 • 63 citations

Formation of Virus Assembly Intermediate Complexes in the Cytoplasm by Wild-Type and Assembly-Defective Mutant Human Immunodeficiency Virus Type 1 and Their Association with Membranes

1999 • 62 citations

CD4 segregates into specific detergent‐resistant T‐cell membrane microdomains

1999 • 56 citations

Lovastatin inhibits HIV-1 expression in H9 human T lymphocytes cultured in cholesterol-poor medium

1994 • 56 citations

Structural changes in the membrane of vero cells infected with a paramyxovirus.

1975 • 49 citations

Recent advances and remaining problems in HIV assembly.

1998 • 47 citations

Resistance Is Futile

2001 • 46 citations

Measles virus matrix protein is not cotransported with the viral glycoproteins but requires virus infection for efficient surface targeting

2002 • 44 citations

Measles Virus Fusion Protein Is Palmitoylated on Transmembrane-Intracytoplasmic Cysteine Residues Which Participate in Cell Fusion

1998 • 43 citations

Asymmetric Requirement for Cholesterol in Receptor-Bearing but Not Envelope-Bearing Membranes for Fusion Mediated by Ecotropic Murine Leukemia Virus

2002 • 41 citations

The Late Stage of Human Immunodeficiency Virus Type 1 Assembly Is an Energy-Dependent Process

2001 • 38 citations

Characterization of Cholesterol-Free Insect Cells Infectible by Baculoviruses: Effects of Cholesterol on VSV Fusion and Infectivity and on Cytotoxicity Induced by Influenza M2 Protein

1997 • 34 citations

Membrane structure

2001 • 25 citations

Inefficient Measles Virus Budding in Murine L.CD46 Fibroblasts

1999 • 24 citations

Electron microscopic evidence for the association of M 2 protein with the influenza virion

1991 • 14 citations

The HIV-1 Nef protein enhances the affinity of reverse transcriptase for RNA in vitro.

2002 • 13 citations

Role of neuraminidase in the morphogenesis of influenza B virus

1994 • 12 citations

Human Immunodeficiency Virus (HIV) Nef is an RNA Binding Protein in Cell-free Systems

1996 • 11 citations

Interaction of HIV-1 Gag and Membranes in a Cell-Free System

2002 • 9 citations