Synthetic Soluble Analogs of Galactosylceramide (GalCer) Bind to the V3 Domain of HIV-1 gp120 and Inhibit HIV-1-induced Fusion and Entry

Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.

1988 • 1,241 citations

An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT

1991 • 994 citations

Identification of the Envelope V3 Loop as the Primary Determinant of Cell Tropism in HIV-1

1991 • 871 citations

Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant

1990 • 665 citations

Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.

1988 • 540 citations

Macrophage and T cell-line tropisms of HIV-1 are determined by specific regions of the envelope gp!20 gene

1991 • 525 citations

Inhibition of Entry of HIV-1 in Neural Cell Lines by Antibodies Against Galactosyl Ceramide

1991 • 523 citations

Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees.

1988 • 514 citations

Broadly Neutralizing Antibodies Elicited by the Hypervariable Neutralizing Determinant of HIV-1

1990 • 358 citations

Viral Fusion Mechanisms

2004 • 309 citations

Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies

1994 • 252 citations

Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor.

1993 • 242 citations

Galactosyl ceramide (or a closely related molecule) is the receptor for human immunodeficiency virus type 1 on human colon epithelial HT29 cells

1992 • 238 citations

Identification of the principal neutralizing determinant of human immunodeficiency virus type 1 as a fusion domain

1991 • 219 citations

Antiviral Agents: Characteristic Activity Spectrum Depending on the Molecular Target With Which They Interact

1993 • 175 citations

Viral Fusion Mechanisms

1993 • 169 citations

The role of the V3 loop of gp 120 in HIV infection

1991 • 165 citations

The V3 region of the envelope glycoprotein of human immunodeficiency virus type 1 binds sulfated polysaccharides and CD4-derived synthetic peptides.

1992 • 153 citations

Characterization of recombinant gp120 and gp160 from HIV-1

1990 • 117 citations

Binding of Human Immunodeficiency Virus Type I (HIV-1) Gp120 to Galactosylceramide (GalCer): Relationship to the V3 Loop

1994 • 106 citations

Suramin inhibits binding of the V3 region of HIV-1 envelope glycoprotein gp120 to galactosylceramide, the receptor for HIV-1 gp120 on human colon epithelial cells.

1994 • 85 citations

Synthetic multimeric peptides derived from the principal neutralization domain (V3 loop) of human immunodeficiency virus type 1 (HIV-1) gp120 bind to galactosylceramide and block HIV-1 infection in a human CD4-negative mucosal epithelial cell line

1995 • 74 citations

Human immunodeficiency virus type 1 infection of SK-N-MC cells: domains of gp120 involved in entry into a CD4-negative, galactosyl ceramide/3' sulfo-galactosyl ceramide-positive cell line

1995 • 73 citations

Tryptase TL₂ in the membrane of human T4⁺ lymphocytes is a novel binding protein of the V3 domain of HIV‐1 envelope glycoprotein gp120

1991 • 48 citations

Identification of the Envelope V3 Loop as a Determinant of a CD4-Negative Neuronal Cell Tropism for HIV-1

1996 • 46 citations

Multibranched V3 peptides inhibit human immunodeficiency virus infection in human lymphocytes and macrophages

1994 • 41 citations

Structure—function relationships of the HIV-1 envelope V3 loop tropism determinant

1993 • 36 citations

Identification of Conserved Residues in the Human Immunodeficiency Virus Type 1 Principal Neutralizing Determinant That Are Involved in Fusion

1991 • 32 citations

Synthesis of Potential Anti-AIDS Amphiphiles. A New Efficient Acylation of Amino-Naphthalene Disulfonic Acid Derivatives

1993 • 6 citations

Genetic determinants controlling HIV-1 tropism for CD4−/GalCer+ human intestinal epithelial cells

1996 • 5 citations

Suramin: A polysulfonated compound that inhibits the binding of HIV-1 gp120 to GalCer/sulfatide and blocks the CD4-independent pathway of HIV-1 infection in mucosal epithelial cells

1996 • 2 citations

Deleted Work

1955 • 0 citations