Comparison of numerous delivery systems for the induction of cytotoxic T lymphocytes by immunization

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Common West African HLA antigens are associated with protection from severe malaria

1991 • 1,570 citations

Cytotoxic T-Cell Immunity to Influenza

1983 • 932 citations

Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

1967 • 928 citations

Malaria: Principles and Practice of Malariology

1989 • 783 citations

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells

1989 • 706 citations

γ Interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites

1987 • 699 citations

Molecular analysis of the association of HLA-B53 and resistance to severe malaria

1992 • 645 citations

In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine

1989 • 632 citations

Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites

1987 • 512 citations

Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria

1989 • 505 citations

CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites.

1988 • 477 citations

NYVAC: A highly attenuated strain of vaccinia virus

1992 • 473 citations

Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.

1994 • 453 citations

Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans.

1995 • 332 citations

Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria.

1993 • 265 citations

Use of the nirB Promoter to Direct the Stable Expression of Heterologous Antigens in Salmonella Oral Vaccine Strains: Development of a Single–Dose Oral Tetanus Vaccine

1992 • 233 citations

Saponin adjuvant induction of ovalbumin-specific CD8+ cytotoxic T lymphocyte responses.

1992 • 224 citations

Oral Salmonella: malaria circumsporozoite recombinants induce specific CD8+ cytotoxic T cells.

1990 • 207 citations

Specificity of protection of man immunized against sporozoite-induced falciparum malaria

1973 • 201 citations

Circumsporozoite protein of Plasmodium berghei: gene cloning and identification of the immunodominant epitopes.

1986 • 198 citations

Protection against malaria by vaccination with sporozoite surface protein 2 plus CS protein

1991 • 188 citations

Sporozoite induced immunity in man against an ethiopian strain of Plasmodium falciparum

1974 • 183 citations

Sporozoite Vaccine Induces Genetically Restricted T Cell Elimination of Malaria from Hepatocytes

1989 • 177 citations

The expression of hybrid HIV:Ty virus-like particles in yeast

1987 • 163 citations

Successful Immunization of Humans with Irradiated Malaria Sporozoites: Humoral and Cellular Responses of the Protected Individuals

1991 • 152 citations

Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria

1995 • 147 citations

Hepatitis B virus small surface antigen particles are processed in a novel endosomal pathway for major histocompatibility complex class I‐restricted epitope presentation

1995 • 146 citations

Efficiency of peptides and lipopeptides for in vivo priming of virus‐specific cytotoxic T cells

1991 • 141 citations

Circumsporozoite protein genes of malaria parasites (Plasmodium spp.): evidence for positive selection on immunogenic regions.

1991 • 126 citations

The cleavage preference of the proteasome governs the yield of antigenic peptides.

1995 • 117 citations

The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules.

1992 • 112 citations

Characterization of a Salmonella typhimurium aro vaccine strain expressing the P.69 antigen of Bordetella pertussis

1992 • 110 citations

Generation of a cytotoxic T‐lymphocyte response using a Salmonella antigen‐delivery system

1990 • 101 citations

The T Cell Response to the Malaria Circumsporozoite Protein: An Immunological Approach to Vaccine Development

1988 • 99 citations

Induction of Cytotoxic T Lymphocytes by Recombinant Canarypox (ALVAC) and Attenuated Vaccinia (NYVAC) Viruses Expressing the HIV-1 Envelope Glycoprotein

1993 • 97 citations

Induction of antigen-specific class I-restricted cytotoxic T cells by soluble proteins in vivo.

1992 • 78 citations

Construction, expression, and immunogenicity of the Schistosoma mansoni P28 glutathione S-transferase as a genetic fusion to tetanus toxin fragment C in a live Aro attenuated vaccine strain of Salmonella.

1994 • 78 citations

Induction of HIV-specific cytotoxic T lymphocytes in vivo with hybrid HIV-1 V3:Ty-virus-like particles.

1993 • 77 citations

Induction of high-titer neutralizing antibodies, using hybrid human immunodeficiency virus V3-Ty viruslike particles in a clinically relevant adjuvant

1991 • 59 citations

Expression of LacZ from thehtrA, nirBandgroEpromoters in aSalmonellavaccine strain: Influence of growth in mammalian cells

1995 • 54 citations

Galactose Oxidation in the Design of Immunogenic Vaccines

1992 • 53 citations

Induction of peptide‐specific primary cytotoxic T lymphocyte responses from human peripheral blood

1995 • 45 citations

Induction of single and dual cytotoxic T‐lymphocyte responses to viral proteins in mice using recombinant hybrid Ty–virus‐like particles

1996 • 38 citations

Attenuated vaccinia virus-circumsporozoite protein recombinants confer protection against rodent malaria

1996 • 37 citations

Enhanced proliferative cellular responses to HIV-1 V3 peptide and gp120 following immunization with V3:Ty virus-like particles.

1992 • 35 citations

Recombinant Salmonella typhimurium strains that invade nonphagocytic cells are resistant to recognition by antigen-specific cytotoxic T lymphocytes

1992 • 32 citations

An HLA-based approach to the design of a CTL-inducing vaccine against Plasmodium falciparum

1994 • 31 citations

Studies using a recombinant vaccinia virus expressing the circumsporozoite protein of Plasmodium berghei

1991 • 23 citations

Mutations with multiple independent origins in surface antigens mark the targets of biological selective pressure

1990 • 15 citations

Nucleotide sequence of the Plasmodium berghei circumsporozoite protein gene from the ANKA clone 2.34L

1990 • 10 citations

Expression Vectors for the Construction of Hybrid Ty-VLPs

2003 • 7 citations

Production and Purification of Hybrid Ty-VLPs

2003 • 6 citations