Accumulation of p53 protein in normal, dysplastic, and neoplastic Barrett's oesophagus

p53 Mutations in Human Cancers

1991 • 8,133 citations

The p53 tumour suppressor gene

1991 • 3,871 citations

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

Chi-Square Tests with One Degree of Freedom; Extensions of the Mantel-Haenszel Procedure

1963 • 2,648 citations

Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections.

1991 • 2,598 citations

p53 function and dysfunction

1992 • 1,918 citations

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

1992 • 1,877 citations

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

1988 • 1,140 citations

Chi-Square Tests with One Degree of Freedom; Extensions of the Mantel- Haenszel Procedure

1963 • 1,099 citations

Chronic peptic ulcerz of the œophagus and ‘œsophagitis’

1950 • 903 citations

An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms

1994 • 513 citations

Adenocarcinoma and Barrett's esophagus. An overrated risk?

1984 • 442 citations

Endoscopic biopsy can detect high-grade dysplasia or early adenocarcinoma in Barrett's esophagus without grossly recognizable neoplastic lesions

1988 • 415 citations

Adenocarcinoma and Barrett's esophagus

1984 • 345 citations

p53 gene mutations in Barrett's epithelium and esophageal cancer.

1991 • 266 citations

Widespread p53 overexpression in human malignant tumors. An immunohistochemical study using methacarn-fixed, embedded tissue.

1992 • 257 citations

Adenocarcinoma in Barrett's oesophagus: an overrated risk.

1989 • 218 citations

p53 protein accumulation in Barrett's metaplasia, dysplasia, and carcinoma: A follow-up study

1993 • 215 citations

Barrett's esophagus: Cell cycle abnormalities in advancing stages of neoplastic progression

1993 • 184 citations

Expression of the nuclear oncogene p53 in colon tumours

1989 • 173 citations

Evaluation of p53 protein expression in Barrett's esophagus by two-parameter flow cytometry

1992 • 165 citations

Loss of heterozygosity of p53 gene and p53 protein expression in human colorectal carcinomas.

1991 • 159 citations

17p allelic deletions and p53 protein overexpression in Barrett's adenocarcinoma.

1991 • 138 citations

p53 expression in colorectal adenomas.

1993 • 84 citations

Detection of p53 in primary lung tumors and nonsmall cell lung carcinoma cell lines.

1991 • 78 citations

Overexpression of p53 protein in Barrett's syndrome with malignant transformation.

1993 • 76 citations

Adenocarcinoma arising in Barrett's oesophagus: evidence for the participation of p53 dysfunction in the dysplasia/carcinoma sequence.

1994 • 61 citations

p53 expression in Barrett's oesophagus, dysplasia, and adenocarcinoma using antibody DO‐7

1994 • 48 citations

Expression of p53 in oligodendrogliomas

1993 • 42 citations

Barrett's oesophagus—cancer risk, biology and therapeutic management

1993 • 35 citations