Human foamy virus Bel1 transactivator contains a bipartite nuclear localization determinant which is sensitive to protein context and triple multimerization domains

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence

1991 • 1,501 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

Functional inactivation of genes by dominant negative mutations

1987 • 1,174 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

Presence of a Potent Transcription Activating Sequence in the p53 Protein

1990 • 811 citations

Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen

1984 • 566 citations

Synthetic peptides as nuclear localization signals

1986 • 472 citations

Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal

1986 • 394 citations

Transcriptional regulation by dimerization: Two sides to an incestuous relationship

1990 • 343 citations

Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.

1990 • 330 citations

Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization

1991 • 312 citations

The nucleoplasmin nuclear location sequence is larger and more complex than that of SV-40 large T antigen.

1988 • 296 citations

Oligomerization and RNA binding domains of the type 1 human immunodeficiency virus Rev protein: a dual function for an arginine-rich binding motif.

1991 • 253 citations

Cyclic-AMP-responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains.

1990 • 236 citations

Characterization of a Dimerization Motif in AP-2 and Its Function in Heterologous DNA-Binding Proteins

1991 • 234 citations

Identification of the sequence responsible for the nuclear accumulation of the influenza virus nucleoprotein in Xenopus oocytes

1985 • 220 citations

The effect of protein context on nuclear location signal function

1987 • 214 citations

Construction of an infectious DNA clone of the full-length human spumaretrovirus genome and mutagenesis of thebel 1 gene

1991 • 157 citations

Co-localization of elements required for phorbol ester stimulation and glucocorticoid repression of proliferin gene expression.

1989 • 154 citations

Human papillomavirus type 18 E7 protein requires intact Cys-X-X-Cys motifs for zinc binding, dimerization, and transformation but not for Rb binding

1993 • 135 citations

Identification of domains involved in nuclear uptake and histone binding of protein N1 of Xenopus laevis.

1988 • 132 citations

Transcription factor interactions: basics on zippers

1991 • 124 citations

Context affects nuclear protein localization in Saccharomyces cerevisiae.

1989 • 124 citations

Function of Two Discrete Regions Is Required for Nuclear Localization of Polymerase Basic Protein 1 of A/WSN/33 Influenza Virus (H1 N1)

1990 • 123 citations

Analysis of splicing patterns of human spumaretrovirus by polymerase chain reaction reveals complex RNA structures

1991 • 115 citations

Characterization of the transcriptional trans activator of human foamy retrovirus

1991 • 105 citations

Mutational Analysis of the Herpes Simplex Virus Type 1 Trans-inducing Factor Vmw65

1988 • 96 citations

Spumaviruses: a group of complex retroviruses.

1991 • 93 citations

The nuclear location signal

1985 • 92 citations

Dominant negative mutants of human T-cell leukemia virus type I Rex and human immunodeficiency virus type 1 Rev fail to multimerize in vivo

1993 • 90 citations

Oligomerization of hepatitis delta antigen is required for both the trans-activating and trans-dominant inhibitory activities of the delta antigen

1992 • 82 citations

The Bel-1 protein of human foamy virus activates human immunodeficiency virus type 1 gene expression via a novel DNA target site

1992 • 57 citations

Genetic evidence that the Tat proteins of human immunodeficiency virus types 1 and 2 can multimerize in the eukaryotic cell nucleus

1993 • 57 citations

Functional organization of the Bel-1 trans activator of human foamy virus

1993 • 54 citations

Context Affects Nuclear Protein Localization in Saccharomyces cerevisiae

1989 • 44 citations

Transactivation of human immunodeficiency virus type 1 long terminal repeat-directed gene expression by the human foamy virus bel1 protein requires a specific DNA sequence

1992 • 43 citations

Multiple positive and negative cis-acting elements that mediate transactivation by bel1 in the long terminal repeat of human foamy virus

1993 • 37 citations

Functional dissection of the human spumaretrovirus transactivator identifies distinct classes of dominant-negative mutants

1993 • 36 citations

Spumaviruses: a group of complex retroviruses.

1991 • 34 citations

Transacting transcriptional activation of human spumaretrovirus LTR in infected cells

1990 • 31 citations

Multimerization of ICP0, a herpes simplex virus immediate-early protein

1992 • 26 citations

The carboxy-terminal transcription enhancement region of the human spumaretrovirus transactivator contains discrete determinants of the activator function

1993 • 26 citations

The Bel1 protein of human foamy virus contains one positive and two negative control regions which regulate a distinct activation domain of 30 amino acids

1994 • 24 citations

Characterisation of the nuclear location sequence of Xenopus nucleoplasmin

1989 • 17 citations