The human beta 2 integrin CD18 promoter consists of two inverted Ets cis elements.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

Cyclic AMP and the induction of eukaryotic gene transcription.

1988 • 1,041 citations

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

1990 • 993 citations

Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

1992 • 980 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 962 citations

Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

1984 • 889 citations

Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

1988 • 845 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 785 citations

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

1992 • 688 citations

c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins.

1991 • 543 citations

Antisense and Antigene Properties of Peptide Nucleic Acids

1992 • 538 citations

The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation

1990 • 507 citations

Association of an Inversion of Chromosome 16 with Abnormal Marrow Eosinophils in Acute Myelomonocytic Leukemia

1983 • 504 citations

Convergence of Ets- and Notch-Related Structural Motifs in a Heteromeric DNA Binding Complex

1991 • 464 citations

The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins

1990 • 417 citations

Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.

1991 • 404 citations

Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motif.

1992 • 381 citations

The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins.

1991 • 380 citations

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.

1992 • 362 citations

Identification of Ets- and Notch-Related Subunits in GA Binding Protein

1991 • 358 citations

Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells.

1992 • 338 citations

The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.

1993 • 317 citations

The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter.

1993 • 315 citations

The ets gene family

1992 • 308 citations

Leukocyte Adhesion Molecules Deficiency: Its Structural Basis, Pathophysiology and Implications for Modulating the Inflammatory Response

1990 • 307 citations

Regulated expression of the Mac-1, LFA-1, p150,95 glycoprotein family during leukocyte differentiation.

1986 • 298 citations

Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promoters.

1993 • 285 citations

Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation

1993 • 278 citations

Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins.

1992 • 267 citations

elk , Tissue-Specific ets -Related Genes on Chromosomes X and 14 Near Translocation Breakpoints

1989 • 261 citations

cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.

1992 • 242 citations

Regulation of lymphoid-specific immunoglobulin mu heavy chain gene enhancer by ETS-domain proteins

1993 • 228 citations

The Sp1 transcription factor binds the CD11b promoter specifically in myeloid cells in vivo and is essential for myeloid-specific promoter activity.

1993 • 212 citations

Molecular interactions within the ecdysone regulatory hierarchy: DNA binding properties of the Drosophila ecdysone-inducible E74A protein

1990 • 195 citations

GATA and Ets cis-Acting Sequences Mediate Megakaryocyte-Specific Expression

1993 • 194 citations

erg , a Human ets -Related Gene on Chromosome 21: Alternative Splicing, Polyadenylation, and Translation

1987 • 178 citations

Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1.

1992 • 160 citations

Organization of the murine Ig-related lambda 5 gene transcribed selectively in pre-B lymphocytes.

1987 • 150 citations

GATA and Ets cis-acting sequences mediate megakaryocyte-specific expression.

1993 • 135 citations

Regulation of the interleukin-1 beta (IL-1 beta) gene by mycobacterial components and lipopolysaccharide is mediated by two nuclear factor-IL6 motifs.

1993 • 131 citations

Differential expression of CD11b/CD18 (Mo1) and myeloperoxidase genes during myeloid differentiation

1989 • 124 citations

A map of the distal region of the long arm of human chromosome 21 constructed by radiation hybrid mapping and pulsed-field gel electrophoresis

1991 • 124 citations

Identification in chickens of an evolutionarily conserved cellular ets-2 gene (c-ets-2) encoding nuclear proteins related to the products of the c-ets proto-oncogene.

1988 • 122 citations

Chromosomal location of the genes encoding the leukocyte adhesion receptors LFA-1, Mac-1 and p150,95. Identification of a gene cluster involved in cell adhesion.

1988 • 112 citations

PU.1 Recruits a Second Nuclear Factor to a Site Important for Immunoglobulin κ 3' Enhancer Activity

1992 • 107 citations

A phorbol ester response element within the human T-cell receptor beta-chain enhancer.

1992 • 103 citations

cDNA Cloning of Transcription Factor E4TF1 Subunits with Ets and Notch Motifs

1993 • 99 citations

The proto-oncogene c-ets is preferentially expressed in lymphoid cells.

1985 • 98 citations

Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia

1987 • 95 citations

Ontogeny of human hematopoietic cells: analysis utilizing monoclonal antibodies.

1983 • 91 citations

Characterization of the ets oncogene family member, fli-1.

1993 • 91 citations

Regulation of expression of the CD11b and CD18 subunits of the neutrophil adherence receptor during human myeloid differentiation

1989 • 83 citations

Characterization of the myeloid-specific CD11b promoter

1992 • 81 citations

Heterogeneously initiated transcription from the pre-B- and B-cell-specific mb-1 promoter: analysis of the requirement for upstream factor-binding sites and initiation site sequences.

1991 • 77 citations

The alpha 5 beta 1 fibronectin receptor. Characterization of the alpha 5 gene promoter.

1991 • 76 citations

Isolation of the human platelet glycoprotein IIb gene and characterization of the 5′ flanking region

1988 • 72 citations

Identification and sequence analysis of the promoter for the leukocyte integrin beta-subunit (CD18): a retinoic acid-inducible gene

1992 • 67 citations

Characterization of the p150,95 leukocyte integrin alpha subunit (CD11c) gene promoter. Identification of cis-acting elements.

1993 • 66 citations

Abnormalities of chromosome 16 in association with acute myelomonocytic leukemia and dysplastic bone marrow eosinophils.

1984 • 65 citations

The promoter of the CD11b gene directs myeloid-specific and developmentally regulated expression.

1991 • 60 citations

erg, an ets-related gene, codes for sequence-specific transcriptional activators.

1991 • 59 citations

Cloning and analysis of the CD18 promoter

1992 • 58 citations

Genetic cause of leukocyte adhesion molecule deficiency. Abnormal splicing and a missense mutation in a conserved region of CD18 impair cell surface expression of beta 2 integrins.

1992 • 56 citations

Human beta 1-integrin gene expression is regulated by two promoter regions.

1993 • 56 citations

Identification of cell-specific and developmentally regulated nuclear factors that direct myeloid and lymphoid expression of the CD11a gene.

1993 • 54 citations

The PU.1 transcription factor is the product of the putative oncogene Spi-1

1990 • 51 citations

cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs.

1993 • 48 citations

Cloning and analysis of the CD18 promoter

1992 • 47 citations

Description of the leukocyte function-associated antigen 1 (LFA-1 or CD11a) promoter.

1993 • 37 citations

Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrins.

1988 • 33 citations

Requirement of an ETS-binding element for transcription of the human lck type I promoter.

1993 • 32 citations

D-elg, a member of the Drosophila ets gene family: sequence, expression and evolutionary comparison.

1991 • 29 citations

Human ETS2 gene on chromosome 21 is not rearranged in Alzheimer disease.

1988 • 17 citations

Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia

1987 • 6 citations