The ets gene family

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

1990 • 993 citations

MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer

1989 • 861 citations

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

1992 • 688 citations

The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation

1990 • 507 citations

Nuclear factor of activated T cells contains Fos and Jun

1992 • 495 citations

Convergence of Ets- and Notch-Related Structural Motifs in a Heteromeric DNA Binding Complex

1991 • 464 citations

A putative second cell-derived oncogene of the avian leukaemia retrovirus E26

1983 • 462 citations

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase.

1992 • 453 citations

Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF

1991 • 447 citations

Tripartite structure of the avian erythroblastosis virus E26 transforming gene

1983 • 430 citations

The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins

1990 • 417 citations

Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.

1991 • 404 citations

The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins.

1991 • 380 citations

A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer.

1991 • 372 citations

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.

1992 • 362 citations

Identification of Ets- and Notch-Related Subunits in GA Binding Protein

1991 • 358 citations

Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells.

1992 • 338 citations

elk , Tissue-Specific ets -Related Genes on Chromosomes X and 14 Near Translocation Breakpoints

1989 • 261 citations

cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.

1992 • 242 citations

c-ets1 proto-oncogene is a transcription factor expressed in endothelial cells during tumor vascularization and other forms of angiogenesis in humans.

1992 • 242 citations

Sequence-Specific Binding of Human Ets-1 to the T Cell Receptor α Gene Enhancer

1990 • 229 citations

Oncogenic conversion by regulatory changes in transcription factors

1991 • 215 citations

PEA3 is a nuclear target for transcription activation by non-nuclear oncogenes.

1989 • 197 citations

Molecular interactions within the ecdysone regulatory hierarchy: DNA binding properties of the Drosophila ecdysone-inducible E74A protein

1990 • 195 citations

Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus.

1990 • 192 citations

Temporal and tissue-specific expression of mouse ets genes.

1987 • 191 citations

The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1.

1990 • 189 citations

The erg gene: a human gene related to the ets oncogene.

1987 • 164 citations

Arabidopsis thaliana contains two genes for TFIID

1990 • 160 citations

Reciprocal expression of human ETS1 and ETS2 genes during T-cell activation: regulatory role for the protooncogene ETS1.

1990 • 146 citations

Role of tryptophan repeats and flanking amino acids in Myb-DNA interactions.

1990 • 146 citations

DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanism.

1992 • 137 citations

The c-ets-1 proto-oncogene has oncogenic activity and is positively autoregulated.

1990 • 126 citations

Identification of nucleotide preferences in DNA sequences recognised specifically by c-Ets-1 protein

1992 • 124 citations

Isoforms of the human ets-1 protein: generation by alternative splicing and differential phosphorylation.

1990 • 101 citations

Definition of an Ets1 Protein Domain Required for Nuclear Localization in Cells and DNA-Binding Activity In Vitro

1989 • 98 citations

Fusion of the nuclear oncoproteins v-Myb and v-Ets is required for the leukemogenicity of E26 virus

1991 • 86 citations

Transcription factor E4TF1 contains two subunits with different functions.

1990 • 82 citations

High-affinity DNA-protein interactions of the cellular ETS1 protein: the determination of the ETS binding motif.

1991 • 78 citations

Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I

1991 • 75 citations

The human ETS1 gene: genomic structure, promoter characterization and alternative splicing.

1991 • 74 citations

The c-ets-1 protein is chromatin associated and binds to DNA in vitro.

1989 • 70 citations

Molecular and functional characterization of the promoter of ETS2, the human c-ets-2 gene.

1990 • 66 citations

A Short-Lived Nuclear Phosphoprotein Encoded by the Human ets-2 Proto-Oncogene Is Stabilized by Activation of Protein Kinase C

1988 • 66 citations

A divergent ets-related protein, elk-1, recognizes similar c-ets-1 proto-oncogene target sequences and acts as a transcriptional activator.

1992 • 62 citations

erg, an ets-related gene, codes for sequence-specific transcriptional activators.

1991 • 59 citations

Alternative splicing within the chicken c-ets-1 locus: implications for transduction within the E26 retrovirus of the c-ets proto-oncogene

1988 • 56 citations

Two independent activation domains in c-Ets-1 and c-Ets-2 located in non-conserved sequences of the ets gene family.

1992 • 54 citations

Rapid and transient expression of Ets2 in mature macrophages following stimulation with cMGF, LPS, and PKC activators.

1990 • 53 citations

Provirus insertion in Tpl-1, an Ets-1-related oncogene, is associated with tumor progression in Moloney murine leukemia virus-induced rat thymic lymphomas.

1989 • 45 citations

Structural and functional analysis of the regulatory sequences of the ets-1 gene.

1991 • 39 citations

A short-lived nuclear phosphoprotein encoded by the human ets-2 proto-oncogene is stabilized by activation of protein kinase C.

1988 • 38 citations

Phosphorylation of the ETS-2 protein: regulation by the T-cell antigen receptor-CD3 complex.

1990 • 38 citations

The ETS genes on chromosome 21 are distal to the breakpoint of the acute myelogenous leukemia translocation (8;21)

1988 • 35 citations

Molecular analysis of the ets genes and their products.

1990 • 34 citations

Identification of a Ets1 variant protein unaffected in its chromatin and in vitro DNA binding capacities by T cell antigen receptor triggering and intracellular calcium rises.

1990 • 31 citations

Expression of a 91-kilodalton PEA3-binding protein is down-regulated during differentiation of F9 embryonal carcinoma cells.

1992 • 30 citations

D-elg, a member of the Drosophila ets gene family: sequence, expression and evolutionary comparison.

1991 • 29 citations

Molecular organization of the chicken ets locus

1988 • 28 citations

Positive and negative factors regulate the transcription of the ETS2 gene via an oncogene-responsive-like unit within the ETS2 promoter region.

1991 • 23 citations

c-ets-1 DNA binding to the PEA3 motif is differentially inhibited by all the mutations found in v-ets.

1992 • 19 citations

The nuclear oncogenes v-erbA and v-ets cooperate in the induction of avian erythroleukemia.

1992 • 13 citations