Rapid generation of inducible mouse mutants

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 2,165 citations

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

1999 • 1,987 citations

Inducible Gene Targeting in Mice

1995 • 1,897 citations

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

1994 • 1,396 citations

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.

1991 • 1,358 citations

Acre-transgenic mouse strain for the ubiquitous deletion ofloxP-flanked gene segments including deletion in germ cells

1995 • 1,269 citations

Regulation of Cre Recombinase Activity by Mutated Estrogen Receptor Ligand-Binding Domains

1997 • 958 citations

Ligand-activated site-specific recombination in mice.

1996 • 885 citations

The pharmacology and clinical uses of tamoxifen

1984 • 873 citations

Conditional control of gene expression in the mouse

2001 • 774 citations

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ERT and Cre-ERT2 recombinases

1999 • 733 citations

B lymphocyte-specific, Cre-mediated mutagenesis in mice

1997 • 696 citations

Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation

2001 • 621 citations

Conditional gene targeting.

1996 • 462 citations

Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

1997 • 438 citations

A highly efficient ligand‐regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

2001 • 340 citations

Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice

1999 • 335 citations

Temporally and spatially regulated somatic mutagenesis in mice

1998 • 187 citations

Bypass of lethality with mosaic mice generated by Cre– loxP -mediated recombination

1996 • 181 citations

Temporally controlled somatic mutagenesis in smooth muscle

2000 • 165 citations

Conditional alleles in mice: Practical considerations for tissue‐specific knockouts

2002 • 157 citations

Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes

2000 • 134 citations

A cre recombinase transgene with mosaic, widespread tamoxifen‐inducible action

2002 • 133 citations

A simple assay to determine the functionality of Cre or FLP recombination targets in genomic manipulation constructs

1996 • 104 citations

Knockout Mice Challenge Our Concepts of Glucose Homeostasis and the Pathogenesis of Diabetes Mellitus

2000 • 47 citations

Ubiquitous postnatal LoxP recombination using a doxycycline auto-inducible Cre transgene (DAI-Cre)

2000 • 23 citations

Conditional gene targeting

1997 • 4 citations

Ubiquitous postnatal LoxP recombination using a doxycycline auto-inducible Cre transgene (DAI-Cre)

2000 • 2 citations