Identification and application of the concepts important for accurate and reliable protein secondary structure prediction

Classification and Regression Trees.

1986 • 21,574 citations

Classification and regression trees

1985 • 11,138 citations

Comparison of the predicted and observed secondary structure of T4 phage lysozyme

1975 • 4,853 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Prediction of protein conformation

1974 • 3,327 citations

Prediction of Protein Secondary Structure at Better than 70% Accuracy

1993 • 2,958 citations

Machine Learning, Neural and Statistical Classification

1995 • 2,125 citations

Database of homology‐derived protein structures and the structural meaning of sequence alignment

1991 • 1,641 citations

Amino Acid Preferences for Specific Locations at the Ends of α Helices

1988 • 1,356 citations

Predicting the secondary structure of globular proteins using neural network models

1988 • 1,243 citations

Computer systems that learn

1990 • 1,110 citations

Principles of protein structure

1980 • 1,094 citations

Principles of Protein Structure

1979 • 1,090 citations

THREE-DIMENSIONAL STRUCTURE OF MEMBRANE AND SURFACE PROTEINS

1984 • 959 citations

Improvements in protein secondary structure prediction by an enhanced neural network

1990 • 708 citations

Further developments of protein secondary structure prediction using information theory

1987 • 573 citations

Protein Design: A Hierarchic Approach

1995 • 532 citations

Structural Basis of Amino Acid α Helix Propensity

1993 • 467 citations

Algorithms for prediction of α-helical and β-structural regions in globular proteins

1974 • 465 citations

Relative helix-forming tendencies of nonpolar amino acids

1990 • 455 citations

Prediction of protein secondary structure and active sites using the alignment of homologous sequences

1987 • 449 citations

Book review: Machine Learning, Neural and Statistical Classification Edited by D. Michie, D.J. Spiegelhalter and C.C. Taylor (Ellis Horwood Limited, 1994)

1996 • 379 citations

α-Helix stability in proteins

1992 • 361 citations

Structural principles of the globular organization of protein chains. A stereochemical theory of globular protein secondary structure

1974 • 355 citations

Redefining the goals of protein secondary structure prediction

1994 • 341 citations

Proceedings Of The 37th Annual Hawaii International Conference On System Sciences

2004 • 333 citations

SOPM: a self-optimized method for protein secondary structure prediction

1994 • 329 citations

STATLOG: COMPARISON OF CLASSIFICATION ALGORITHMS ON LARGE REAL-WORLD PROBLEMS

1995 • 321 citations

Prediction of Protein Secondary Structure by Combining Nearest-neighbor Algorithms and Multiple Sequence Alignments

1995 • 306 citations

Conformational properties of amino acid residues in globular proteins

1976 • 278 citations

Protein secondary structure prediction using logic-based machine learning

1992 • 246 citations

Hybrid system for protein secondary structure prediction

1992 • 230 citations

Secondary structure prediction: combination of three different methods

1988 • 199 citations

Amino and carboxy-terminal regions in globular proteins

1983 • 187 citations

Patterns of divergence in homologous proteins as indicators of secondary and tertiary structure: A prediction of the structure of the catalytic domain of protein kinases

1991 • 173 citations

Protein Secondary Structure Prediction Using Nearest-neighbor Methods

1993 • 165 citations

Secondary structure predictions and medium range interactions

1987 • 163 citations

Generating and testing protein folds

1993 • 158 citations

RNA Secondary Structure

2018 • 153 citations

Comparison of three algorithms for the assignment of secondary structure in proteins: the advantages of a consensus assignment

1993 • 127 citations

Secondary structure assignment for .alpha./.beta. proteins by a combinatorial approach

1983 • 122 citations

Machine learning approach for the prediction of protein secondary structure

1990 • 108 citations

A simple and fast approach to prediction of protein secondary structure from multiply aligned sequences with accuracy above 70%

1995 • 88 citations

Protein Structure Prediction: A Practical Approach

1997 • 85 citations

The Limits of Protein Secondary Structure Prediction Accuracy from Multiple Sequence Alignment

1993 • 77 citations

Use of Amino Acid Environment-dependent Substitution Tables and Conformational Propensities in Structure Prediction from Aligned Sequences of Homologous Proteins. II. Secondary Structures

1994 • 63 citations

Predicting α-helix and β-strand segments of globular proteins

1994 • 62 citations

Secondary structure prediction of all-helical proteins in two states

1993 • 61 citations

Amino acid preferences of small proteins

1992 • 57 citations

β-Breakers: An aperiodic secondary structure

1991 • 46 citations

Low resolution structure of adenylate kinase

1973 • 39 citations

Secondary structure prediction

1992 • 37 citations

The superarticulacy phenomenon in the context of software manufacture

1990 • 26 citations

Predicting the conformation of proteins man versus machine

1993 • 26 citations

Technology Lecture: The superarticulacy phenomenon in the context of software manufacture

1986 • 20 citations

Evaluating Predictions of Secondary Structure in Proteins

1994 • 19 citations

A decision graph explanation of protein secondary structure prediction

2002 • 11 citations