β-Breakers: An aperiodic secondary structure

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

The Anatomy and Taxonomy of Protein Structure

1981 • 3,376 citations

Prediction of protein conformation

1974 • 3,327 citations

The structure of proteins: Two hydrogen-bonded helical configurations of the polypeptide chain

1951 • 2,750 citations

Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins

1974 • 2,173 citations

Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three linked peptide units

1968 • 1,497 citations

Chemical and biological evolution of a nucleotide-binding protein

1974 • 1,457 citations

Amino Acid Preferences for Specific Locations at the Ends of α Helices

1988 • 1,356 citations

Structural patterns in globular proteins

1976 • 1,286 citations

Predicting the secondary structure of globular proteins using neural network models

1988 • 1,243 citations

Prediction of the occurrence of the ADP-binding βαβ-fold in proteins, using an amino acid sequence fingerprint

1986 • 1,172 citations

Hydrophobicity of Amino Acid Residues in Globular Proteins

1985 • 1,168 citations

THE KINETICS OF FORMATION OF NATIVE RIBONUCLEASE DURING OXIDATION OF THE REDUCED POLYPEPTIDE CHAIN

1961 • 1,148 citations

Analysis and prediction of the different types of β-turn in proteins

1988 • 962 citations

β-turns in proteins

1977 • 960 citations

THREE-DIMENSIONAL STRUCTURE OF MEMBRANE AND SURFACE PROTEINS

1984 • 959 citations

The MIDAS display system

1988 • 955 citations

Structure of prealbumin: Secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 Å

1978 • 784 citations

Configurations of Polypeptide Chains With Favored Orientations Around Single Bonds

1951 • 778 citations

Using known substructures in protein model building and crystallography.

1986 • 766 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 735 citations

Improvements in protein secondary structure prediction by an enhanced neural network

1990 • 708 citations

AMINOACYL tRNA SYNTHETASES: GENERAL SCHEME OF STRUCTURE-FUNCTION RELATIONSHIPS IN THE POLYPEPTIDES AND RECOGNITION OF TRANSFER RNAS

1987 • 535 citations

Refined structure of human carbonic anhydrase II at 2.0 Å resolution

1988 • 530 citations

Structure of papain refined at 1.65 Å resolution

1984 • 508 citations

Automatic identification of secondary structure in globular proteins

1977 • 507 citations

Protein secondary structure prediction with a neural network.

1989 • 506 citations

Structure of thermolysin refined at 1.6 Å resolution

1982 • 443 citations

Identification of structural motifs from protein coordinate data: Secondary structure and first‐level supersecondary structure*

1988 • 409 citations

β-Turns and their distortions: a proposed new nomenclature

1990 • 393 citations

Refined crystal structure of carboxypeptidase a at 1·54 Å resolution

1983 • 391 citations

The protein identification resource (PIR)

1988 • 389 citations

On the use of sequence homologies to predict protein structure: identical pentapeptides can have completely different conformations.

1984 • 386 citations

Packing of α-helices: Geometrical constraints and contact areas

1978 • 366 citations

The covalent and three-dimensional structure of concanavalin A. IV. Atomic coordinates, hydrogen bonding, and quaternary structure.

1975 • 362 citations

Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin new at 2.0 A resolution.

1978 • 293 citations

Automatic generation of primary sequence patterns from sets of related protein sequences.

1990 • 292 citations

Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim.

1985 • 273 citations

A 3D building blocks approach to analyzing and predicting structure of proteins

1989 • 252 citations

Refined structure of porcine cytosolic adenylate kinase at 2.1 Å resolution

1988 • 243 citations

Structure of the semiquinone form of flavodoxin from Clostridium MP

1977 • 221 citations

Turn prediction in proteins using a pattern-matching approach

1986 • 212 citations

The role of internal packing interactions in determining the structure and stability of a protein

1991 • 208 citations

Antiparallel and parallel β-strands differ in amino acid residue preferences

1979 • 206 citations

The protein identification resource (PIR)

1986 • 195 citations

Relation between structure and function of α/β–protejns

1980 • 194 citations

Phosphofructokinase: structure and control

1981 • 183 citations

Refined crystal structure of dogfish M4 apo-lactate dehydrogenase

1987 • 182 citations

Crystallographic refinement of rubredoxin at 1·2 Å resolution

1980 • 178 citations

Handedness of crossover connections in beta sheets.

1976 • 177 citations

On the conformation of proteins: The handedness of the β-strand-α-helix-β-strand unit

1976 • 175 citations

Identification of predictive sequence motifs limited by protein structure data base size

1988 • 160 citations

Interdomain motion in liver alcohol dehydrogenase. Structural and energetic analysis of the hinge bending mode.

1986 • 156 citations

Refined crystal structure of cytoplasmic malate dehydrogenase at 2.5-.ANG. resolution

1989 • 149 citations

The Structure of Cytochrome b5 at 2.0 A Resolution

1972 • 143 citations

Isolation, sequence analysis, and transcriptional studies of the flavodoxin gene from Anacystis nidulans R2

1988 • 142 citations

Analysis and prediction of the packing of α-helices against a β-sheet in the tertiary structure of globular proteins

1982 • 141 citations

On the conformation of proteins: The handedness of the connection between parallel β-strands

1977 • 128 citations

Describing protein structure: A general algorithm yielding complete helicoidal parameters and a unique overall axis

1989 • 127 citations

Secondary structure assignment for .alpha./.beta. proteins by a combinatorial approach

1983 • 122 citations

Atomic coordinates for subtilisin BPN′ (or Novo)

1971 • 120 citations

Atomic coordinates for triose phosphate isomerase from chicken muscle

1976 • 116 citations

Automatic definition of recurrent local structure motifs in proteins

1990 • 112 citations

Prediction of super-secondary structure in proteins

1983 • 109 citations

Amino acid distribution in protein secondary structures

1982 • 94 citations

Structure of the l-leucine-binding protein refined at 2.4 Å resolution and comparison with the Leu/Ile/Val-binding protein structure

1989 • 94 citations

Structure of oxidized flavodoxin from Anacystis nidulans

1983 • 94 citations

Protein secondary structure

1982 • 93 citations

Transfer of a β-turn structure to a new protein context

1989 • 92 citations

Synthesis, purification and initial structural characterization of octarellin, a de novo polypeptide modelled on the α/β-barrel Proteins

1990 • 85 citations

Structural determinants of the conformations of medium‐sized loops in proteins

1989 • 77 citations

Structural and sequence patterns in the loops of βαβ units

1987 • 73 citations

Pattern recognition in the prediction of protein structure. I. Tripeptide conformational probabilities calculated from the amino acid sequence

1989 • 58 citations

The Tryptophan Synthase Multienzyme Complex: Exploring Structure-Function Relationships with X-Ray Crystallography and Mutagenesis

1990 • 48 citations

A helix–turn–strand structural motif common in α–β proteins

1990 • 39 citations

The amino acid sequence of a flavodoxin from the eukaryotic red alga Chondrus crispus

1989 • 31 citations

β-Turn-driven early evolution: The genetic code and biosynthesis pathways

1987 • 28 citations

Preliminary x-ray data on crystals of mandelate racemase.

1988 • 13 citations