Imidazenil, a positive allosteric GABAA receptor modulator, inhibits the effects of cocaine on locomotor activity and extracellular dopamine in the nucleus accumbens shell without tolerance liability.

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Cellular and Molecular Mechanisms of Drug Dependence

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The dopamine hypothesis of the reinforcing properties of cocaine

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Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—1. Identification and characterization

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Neurotransmitter regulation of dopamine neurons in the ventral tegmental area

1993 • 713 citations

Microdialysis—Theory and application

1990 • 651 citations

Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro

1990 • 507 citations

Two cell types in rat substantia nigra zona compacta distinguished by membrane properties and the actions of dopamine and opioids

1989 • 426 citations

Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents.

1991 • 338 citations

Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: studies in the ventral tegmental area

1988 • 313 citations

Synaptic Regulation of Mesocorticolimbic Dopamine Neurons

1996 • 289 citations

Role of Dopamine D₁and D₂Receptors in the Nucleus Accumbens in Mediating Reward

1997 • 248 citations

Nigral Dopamine Neurons: Intracellular Recording and Identification with L-Dopa Injection and Histofluorescence

1980 • 239 citations

Inhibition of cortical acetylcholine release and cognitive performance by histamine H₃ receptor activation in rats

1996 • 228 citations

Cell cycle-dependent cytotoxicity, G2/M phase arrest, and disruption of p34cdc2/cyclin B1 activity induced by doxorubicin in synchronized P388 cells.

1996 • 206 citations

D1 dopamine receptors in the nucleus accumbens modulate cocaine self-administration in the rat

1993 • 157 citations

Benzodiazepines on trial: a research strategy for their rehabilitation

1996 • 144 citations

Chlordiazepoxide selectively potentiates GABA conductance of spinal cord and sensory neurons in cell culture.

1981 • 128 citations

Modifications of gamma-aminobutyric acidA receptor subunit expression in rat neocortex during tolerance to diazepam.

1996 • 117 citations

GABAergic attenuation of cocaine-induced dopamine release and locomotor activity

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gamma-Aminobutyric acid gating of Cl- channels in recombinant GABAA receptors.

1995 • 102 citations

Serotonin potentiates ethanol-induced excitation of ventral tegmental area neurons in brain slices from three different rat strains.

1995 • 92 citations

Actions of benzodiazepine and beta-carboline derivatives on gamma-aminobutyric acid-activated Cl- channels recorded from membrane patches of neonatal rat cortical neurons in culture.

1987 • 87 citations

Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors.

1993 • 85 citations

Molecular mechanisms of the partial allosteric modulatory effects of bretazenil at gamma-aminobutyric acid type A receptor.

1992 • 79 citations

Intracellular recording from putative dopamine-containing neurons in the ventral tegmental area of Tsai in a brain slice preparation

1989 • 67 citations

Effects of alprazolam on intravenous cocaine self-administration in rats

1993 • 66 citations

Cholecystokinin potentiates dopamine inhibition of mesencephalic dopamine neurons in vitro

1987 • 64 citations

Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations.

1995 • 56 citations

Imidazenil, a partial positive allosteric modulator of GABAA receptors, exhibits low tolerance and dependence liabilities in the rat.

1994 • 47 citations

Reversible Modification of GABA A Receptor Subunit mRNA Expression During Tolerance to Diazepam-induced Cognition Dysfunction

1996 • 43 citations

Chronic administration of an anticonvulsant dose of imidazenil fails to induce tolerance of GABAA receptor function in mice

1994 • 25 citations

)"Imidazenil : a new partial positive allosteric modulator of GABA action at GABAA receptors."

1993 • 8 citations