Induction of cytokines in phagocytic mammalian cells infected with virulent and avirulent Listeria strains

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

CELLULAR RESISTANCE TO INFECTION

1962 • 1,422 citations

Role of hemolysin for the intracellular growth of Listeria monocytogenes.

1988 • 881 citations

L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein

1992 • 790 citations

In vitro model of penetration and intracellular growth of Listeria monocytogenes in the human enterocyte-like cell line Caco-2

1987 • 714 citations

Epidemiology of human listeriosis

1991 • 652 citations

Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level.

1990 • 495 citations

A novel bacterial virulence gene in Listeria monocytogenes required for host cell microfilament interaction with homology to the proline-rich region of vinculin.

1992 • 411 citations

Coordinate regulation of virulence genes in Listeria monocytogenes requires the product of the prfA gene

1992 • 404 citations

Nucleotide sequence of the lecithinase operon of Listeria monocytogenes and possible role of lecithinase in cell-to-cell spread

1992 • 393 citations

Purification and physico-chemical characterization of rabbit tumor necrosis factor.

1980 • 386 citations

Identification of Macrophage-Like Characteristics in a Cultured Murine Tumor Line

1975 • 374 citations

Tn916-induced mutations in the hemolysin determinant affecting virulence of Listeria monocytogenes

1987 • 342 citations

Identification of a gene that positively regulates expression of listeriolysin, the major virulence factor of listeria monocytogenes.

1990 • 293 citations

Expression in Escherichia coli and sequence analysis of the listeriolysin O determinant of Listeria monocytogenes

1988 • 286 citations

Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro

1992 • 234 citations

In vivo cytokine gene expression in T cell subsets of the autoimmune MRL/Mp‐lpr/lpr mouse

1990 • 219 citations

Identification of phosphatidylinositol‐specific phospholipase C activity in Listeria monocytogenes: a novel type of virulence factor?

1991 • 195 citations

Cholera toxin stimulates IL-1 production and enhances antigen presentation by macrophages in vitro.

1991 • 192 citations

Hemolysin supports survival but not entry of the intracellular bacterium Listeria monocytogenes

1988 • 192 citations

The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation.

1987 • 177 citations

Detection of a gene encoding a phosphatidylinositol‐specific phospholipase C that is co‐ordinately expressed with listeriolysin in Listeria monocytogenes

1991 • 160 citations

Endogenous tumor necrosis factor, interleukin-6, and gamma interferon levels during Listeria monocytogenes infection in mice

1992 • 147 citations

Analysis of cytokine mRNA levels in interleukin‐4‐transgenic mice by quantitative polymerase chain reaction

1992 • 139 citations

Molecular cloning, sequencing, and identification of a metalloprotease gene from Listeria monocytogenes that is species specific and physically linked to the listeriolysin gene

1991 • 132 citations

Identification of a new operon involved in Listeria monocytogenes virulence: its first gene encodes a protein homologous to bacterial metalloproteases

1991 • 122 citations

Tumor necrosis factor-independent IL-6 production during murine listeriosis.

1991 • 117 citations

Kinetic analysis of cytokine gene expression in the livers of naive and immune mice infected with Listeria monocytogenes. The immediate early phase in innate resistance and acquired immunity.

1992 • 113 citations

Surface‐associated, PrfA‐regulated proteins of Listeria monocytogenes synthesized under stress conditions

1993 • 104 citations

Synthesis and secretion of interferon by murine fibroblasts in response to intracellular Listeria monocytogenes

1986 • 88 citations

Murine macrophage activation by staphylococcal exotoxins

1991 • 68 citations

Role of listeriolysin-O (LLO) in the T lymphocyte response to infection with Listeria monocytogenes. Identification of T cell epitopes of LLO.

1991 • 68 citations

Difference in the induction of macrophage interleukin-1 production between viable and killed cells of Listeria monocytogenes

1990 • 57 citations

Cytokine expression in vivo during murine listeriosis. Infection with live, virulent bacteria is required for monokine and lymphokine messenger RNA accumulation in the spleen.

1992 • 45 citations

Mutations affecting hemolysin production inListeria monocytogeneslocated outside the listeriolysin gene

1989 • 43 citations

Early expression of cytokine mRNA in mice infected with Listeria monocytogenes

1992 • 40 citations

Bacterial Adherence and Epithelial Cell Cytokine Production

1993 • 20 citations