Relations among aging, antioxidant status, and cataract

The Framingham Eye Study monograph: An ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2631 adults, 1973-1975.

1980 • 1,269 citations

Antioxidant defenses and lipid peroxidation in human blood plasma.

1988 • 1,253 citations

Free radical tissue damage: protective role of antioxidant nutrients ¹

1987 • 1,210 citations

Glutathione-ascorbic acid antioxidant system in animals

1994 • 825 citations

Antioxidant defense systems: the role of carotenoids, tocopherols, and thiols

1991 • 781 citations

Effect of Ultraviolet Radiation on Cataract Formation

1988 • 730 citations

New Concepts in the Biology and Biochemistry of Ascorbic Acid

1986 • 650 citations

The Lens Opacities Case-Control Study

1991 • 594 citations

Prevalence of Age-related Lens Opacities in a Population

1992 • 574 citations

Biochemistry of the Eye

1991 • 444 citations

The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin E

1988 • 397 citations

The influence of smoking on vitamin C status in adults.

1989 • 343 citations

The Beaver Dam Eye Study: The Relation of Age-related Maculopathy to Smoking

1993 • 333 citations

India-US Case-Control Study of Age-Related Cataracts

1989 • 319 citations

Nutrient intake and cataract extraction in women: a prospective study.

1992 • 316 citations

Oxidative stress on lens and cataract formation: role of light and oxygen

1984 • 305 citations

Interaction of Oxygen and Oxy-radicals With Carotenoids<xref ref-type="fn" rid="FN1">1</xref>

1982 • 300 citations

Epidemiologic evidence of a role for the antioxidant vitamins and carotenoids in cataract prevention

1991 • 265 citations

Prevalence and aetiology of cataract in Punjab.

1982 • 222 citations

The Linxian Cataract Studies

1993 • 222 citations

Natural antioxidants in human health and disease

1995 • 218 citations

A Prospective Study of Cigarette Smoking and Risk of Cataract in Men

1992 • 204 citations

Measurement of carotenoids, retinoids, and tocopherols in human lenses.

1995 • 204 citations

Biokinetics of dietaryRRR‐α‐tocopherol in the male guinea pig at three dietary levels of vitamin C and two levels of vitamin E. Evidence that vitamin C does not “spare” vitamin Ein vivo

1990 • 197 citations

Protein oxidation and loss of protease activity may lead to cataract formation in the aged lens

1987 • 196 citations

Serum antioxidant vitamins and risk of cataract.

1992 • 178 citations

Cigarette Smoking and Risk of Nuclear Cataracts

1989 • 166 citations

Nutritional Factors in Cataract

1990 • 162 citations

Sunlight and human cataracts.

1979 • 161 citations

Plasma Antioxidants and Risk of Cortical and Nuclear Cataract

1993 • 161 citations

Visual problems in the elderly population and implications for services.

1992 • 156 citations

Vitamin E Intake and Risk of Cataracts in Humans^a

1989 • 156 citations

Oxidative stress and recovery from oxidative stress are associated with altered ubiquitin conjugating and proteolytic activities in bovine lens epithelial cells

1995 • 156 citations

ASSOCIATIONS AMONG CATARACT PREVALENCE, SUNLIGHT HOURS, AND ALTITUDE IN THE HIMALAYAS1

1983 • 152 citations

A Prospective Study of Cigarette Smoking and Risk of Cataract Surgery in Women

1992 • 152 citations

The use of vitamin supplements and the risk of cataract among US male physicians.

1994 • 136 citations

Carotenoid Analyses of Selected Raw and Cooked Foods Associated With a Lower Risk for Cancer

1990 • 132 citations

Micronutrients in health and in disease prevention

1991 • 127 citations

Functional Blindness and Visual Impairment in Older Adults from Three Communities

1992 • 124 citations

Relationship in humans between ascorbic acid consumption and levels of total and reduced ascorbic acid in lens, aqueous humor, and plasma

1991 • 122 citations

Visual Impairment in a Rural Appalachian Community

1990 • 119 citations

Isolation and characterization of a blue fluorophore from human eye lens crystallins: In vitro formation from Maillard reaction with ascorbate and ribose

1992 • 115 citations

The role of glutathione metabolism in the detoxification of H2O2 in rabbit lens.

1982 • 109 citations

THE RELATIONSHIP OF PLASMA CAROTENOIDS TO HEALTH AND BIOCHEMICAL FACTORS IN MIDDLE-AGED MEN1

1985 • 103 citations

The conquest of cataract: a global challenge

1985 • 102 citations

In vivo measurements of oxygen tension in the cornea, aqueous humor, and anterior lens of the open eye.

1972 • 94 citations

Singlet oxygen as a possible factor in human senile nuclear cataract development

1984 • 94 citations

Blindness and eye disease in Kenya: ocular status survey results from the Kenya Rural Blindness Prevention Project.

1990 • 89 citations

Relation between Lens Opacities and Vitamin and Mineral Supplement Use

1994 • 87 citations

Relationship between Dietary Intake and Tissue Levels of Reduced and Total Vitamin C in the Nonscorbutic Guinea Pig

1989 • 85 citations

Ascorbic acid and the eye

1991 • 82 citations

Nutrition in the elderly : the Boston nutritional status survey

1992 • 79 citations

Canthaxanthin retinopathy

1987 • 68 citations

Oxidation and Aging: Impact on Vision

1993 • 67 citations

Ubiquitin and ubiquitin conjugates in human lens

1992 • 62 citations

Effect of vitamin E on glutathione content in red blood cells, aqueous humor and lens of humans and other species

1986 • 59 citations

Effects of near ultraviolet radiation on the lens and retina

1983 • 55 citations

Measures of leucine aminopeptidase can be used to anticipate UV-induced age-related damage to lens proteins: Ascorbate can delay this damage

1987 • 48 citations

Oxygen: aspects of its toxicity and elements of defense

1984 • 45 citations

The Photoreceptor G-Protein Transducin (Gt) Is a Substrate for Ubiquitin-Dependent Proteolysis

1994 • 45 citations

Bovine lens epithelial cells have a ubiquitin-dependent proteolysis system

1993 • 41 citations

Reduced and total ascorbate in guinea pig eye tissues in response to dietary intake

1988 • 38 citations

CATARACT BLINDNESS IN DEVELOPING NATIONS

1990 • 32 citations

Visual disability and major causes of blindness in NSW: A study of people aged 50 and over attending the Royal Blind Society 1984 to 1989

1991 • 30 citations

Evidence for ATP and ubiquitin dependent degradation of proteins in cultured bovine lens epithelial cells

1991 • 27 citations

Glutathione synthesis and glutathione redox pathways in naphthalene cataract of the rat

1990 • 27 citations

In vitro effect of alpha-tocopherol on lysophosphatidylcholine-induced lens damage

1985 • 26 citations

Relationships between Natural Antioxidants and Cataract Formation

1994 • 23 citations

Vitamin E in human neural retina and retinal pigment epithelium: Effect of age

1987 • 20 citations

Prevalence of age-related cataract in Ganzi and Shanghai. The Epidemiological Study Group.

1990 • 17 citations

Congressional Testimony

2023 • 16 citations

Relationship between long-term vitamin C intake and prevalence of cataract and macular degeneration

1992 • 6 citations

Relationship between long-term vitamin C intake and prevalence of catract and macular degeneration

1992 • 5 citations

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