Oxidative stress on lens and cataract formation: role of light and oxygen

Superoxide Dismutase

1969 • 12,578 citations

Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels

1971 • 11,879 citations

The Role of Superoxide Anion in the Autoxidation of Epinephrine and a Simple Assay for Superoxide Dismutase

1972 • 8,501 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

The Biology of Oxygen Radicals

1978 • 3,361 citations

The catalytic decomposition of hydrogen peroxide by iron salts

1934 • 2,483 citations

Superoxide Dismutases

1975 • 1,673 citations

Lipid peroxidation damage to cell components.

1973 • 925 citations

Superoxide‐dependent production of hydroxyl radical catalyzed by iron—EDTA complex

1978 • 876 citations

Theory of Transparency of the Eye

1971 • 876 citations

The thiobarbituric acid reaction and the autoxidations of polyunsaturated fatty acid methyl esters

1962 • 823 citations

THE DISTRIBUTION OF VITAMIN C IN PLANT AND ANIMAL TISSUES, AND ITS DETERMINATION

1933 • 388 citations

FUNCTIONAL and STRUCTURAL ASPECTS OF BIOLOGICAL MEMBRANES: A SUGGESTED STRUCTURAL ROLE FOR VITAMIN E IN THE CONTROL OF MEMBRANE PERMEABILITY and STABILITY

1972 • 388 citations

THE NATURE OF THE CHEMICAL BOND. II. THE ONE-ELECTRON BOND AND THE THREE-ELECTRON BOND

1931 • 369 citations

Progress in the Chemistry of Fats and Other Lipids.

1954 • 358 citations

Lipid peroxidation: its measurement, occurrence, and significance in animal tissues.

1967 • 250 citations

Light-induced damage to ocular lens cation pump: prevention by vitamin C.

1979 • 225 citations

Molecular mechanism of cataractogenesis: III. Toxic metabolites of oxygen as initiators of lipid peroxidation and cataract

1984 • 219 citations

Autoxidation of fats and related substances

1954 • 218 citations

Ascorbic acid, metal ions and the superoxide radical

1976 • 196 citations

The Human Lens: In Relation to Cataract

1974 • 180 citations

On the presence and mechanism of formation of heavy molecular weight aggregates in human normal and cataractous lenses

1973 • 162 citations

The reaction between the superoxide anion radical and cytochrome c

1975 • 143 citations

Photoperoxidation in Lens and Cataract Formation: Preventive Role of Superoxide Dismutase, Catalase and Vitamin C

1982 • 132 citations

The effect of vitamin E on the oxidation state of selenium in rat liver

1971 • 102 citations

Studies on the structural proteins of the human lens

1969 • 101 citations

Singlet oxygen as a possible factor in human senile nuclear cataract development

1984 • 94 citations

Age-dependent changes in the molecular size of human lens proteins and their relationship to light scatter.

1974 • 92 citations

The effect of vitamin E deficiency on the vitamin A reserves of the rat

1940 • 91 citations

Protection against Superoxide Radicals in Rat Lens

1977 • 90 citations

Age-dependent changes in the structure of alpha crystallin.

1971 • 73 citations

A Light-catalysed Reaction in the Aqueous Humour of the Eye

1965 • 64 citations

Changes in Lens Proteins of Rats During Aging

1956 • 64 citations

PHOTOPEROXIDATION OF LENS LIPIDS: PREVENTION BY VITAMIN E

1982 • 64 citations

ROLE OF VITAMIN E, SELENIUM, AND RELATED FACTORS IN EXPERIMENTAL NUTRITIONAL LIVER DISEASE.

1965 • 62 citations

The Emory mouse cataract: An animal model for human senile cataract

1981 • 62 citations

VITAMIN E AND METABOLIC REGULATION*

1972 • 54 citations

The discovery of the superoxide radical

1979 • 50 citations

Increased lipid peroxidation and altered membrane functions in Emory mouse cataract

1982 • 49 citations

A lipid peroxidative mechanism for posterior subcapsular cataract formation in the rabbit: a possible model for cataract formation in tapetoretinal diseases.

1984 • 49 citations

Studies on the crystalline lens. IV. Distribution of cytochrome, total riboflavin, lactate, and pyruvate and their metabolic significance.

1951 • 47 citations

Photodynamic effects of rose bengal or riboflavin on carrier-mediated transport systems in rat lens

1981 • 46 citations

The effect of hydrogen peroxide on the rubidium transport of the rat lens

1976 • 39 citations

Fluorescent derivatives of 3-hydroxy-<scp>L</scp>-kynurenine in the lens of man, the baboon and the grey squirrel

1971 • 39 citations

Accumulation of rubidium-86 by the rabbit lens.

1962 • 37 citations

STUDIES ON THE CRYSTALLINE LENS

1951 • 37 citations

Photo-oxidation of proteins and comparison of photo-oxidized proteins with those of the cataractous human lens.

1972 • 36 citations

Ascorbate Transport in Guinea Pig Eyes

1967 • 32 citations

Role of sulfhydryl groups in the formation of a hereditary cataract in the rat

1975 • 30 citations

Contemporary Ophthalmology

1973 • 30 citations

Superoxide and lens of the eye: A new theory of cataractogenesis

1981 • 30 citations

Lens proteins and fluorescence.

1972 • 28 citations

The Influence of Oxygen on the Photodynamic Action of Methylene Blue on Cation Transport in the Rabbit Lens*

1959 • 28 citations

Investigation of the Blood-Aqueous Barrier in the Newborn*

1949 • 25 citations

Riboflavin and riboflavin adenine dinucleotide in ox ocular tissues

1943 • 24 citations

Effects of singlet oxygen on human lens crystallins in vitro.

1981 • 23 citations

Antioxidant effects in biochemistry and physiology

1964 • 13 citations

Determination of the solvent accessibility of specific aromatic residues in gammacrystallin by photo-CIDNP NMR measurements

1984 • 12 citations

Lens glutathione depletion of 1-chloro-2,4-dinitrobenzene and oxidative stress

1984 • 8 citations