Mutations in the p53 gene in radiation-sensitive and -resistant human squamous carcinoma cells.

The p53 tumour suppressor gene

1991 • 3,871 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

1992 • 1,877 citations

Ionizing radiation regulates expression of the c-jun protooncogene.

1990 • 297 citations

Elevated P53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck

1991 • 259 citations

Expression of p53 in premalignant and malignant squamous epithelium.

1991 • 237 citations

Effect of Antisense c- raf -1 on Tumorigenicity and Radiation Sensitivity of a Human Squamous Carcinoma

1989 • 189 citations

Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients.

1986 • 176 citations

Radioresistant tumor cells are present in head and neck carcinomas that recur after radiotherapy

1988 • 169 citations

Mutant p53 proteins bind DNA abnormally in vitro.

1991 • 166 citations

Detection of aberrations of the p53 alleles and the gene transcript in human tumor cell lines by single-strand conformation polymorphism analysis.

1991 • 165 citations

Biological Consequences of Gene Regulation After Ionizing Radiation Exposure

1991 • 160 citations

The raf Oncogene Is Associated with a Radiation-Resistant Human Laryngeal Cancer

1987 • 150 citations

Keynote address—the problem: Tumor radioresistance in clinical radiotherapy

1982 • 126 citations

Oncogenes in Radioresistant, Noncancerous Skin Fibroblasts from a Cancer-Prone Family

1987 • 111 citations

Predictive Assays of Tumor Radiocurability

1988 • 99 citations

Activation of c-myc and c-K-ras Oncogenes in Primary Rat Tumors induced by Ionizing Radiation

1987 • 91 citations

T-antigen mutant activities in vivo: roles of p53 and pRB binding in tumorigenesis of the choroid plexus.

1992 • 80 citations

Differential Expression of Proteins in Radioresistant and Squamous Carcinoma Cells

1992 • 23 citations