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L-Triiodothyronine (T3) Regulates Cellular Growth Rate, Growth Hormone Production, and Levels of Nuclear T3Receptors via Distinct Dose-Response Ranges in Cultured GC Cells

Data up to Jan 2025

Published1990
Citations14
References27

Total Citations Per Year

Abstract

References (27)

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Glucocorticoid receptor binds cooperatively to adjacent recognition sites.

1989 • 142 citations

Dose-dependent depletion of nuclear receptors by L-triiodothyronine: evidence for a role in induction of growth hormone synthesis in cultured GH1 cells.

1976 • 139 citations

Modulation of thyroid hormone nuclear receptor levels by 3,5,3'-triiodo-L-thyronine in GH1 cells. Evidence for two functional components of nuclear-bound receptor and relationship to the induction of growth hormone synthesis.

1977 • 124 citations

Concentration of l-Thyroxine and l-Triiodothyronine Specifically Bound to Nuclear Receptors in Rat Liver and Kidney

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1978 • 94 citations

Regulation of thyroid hormone nuclear receptor levels in GH1 cells by 3,5,3'-triiodo-L-thyronine. Use of dense amino acid labeling to determine the influence of hormone on the receptor half-life and the rate of appearance of newly synthesized receptor.

1981 • 85 citations

Preparation, Purification, and Stability of High Specific Activity125I-Labeled Thyronines*

1978 • 61 citations

L-Triiodothyronine (T3) Stimulates Growth of Cultured GC Cells by Action Early in the Gi Period: Evidence for Mediation by the Nuclear T3Receptor*

1985 • 40 citations

TRIIODOTHYRONINE STIMULATES GROWTH OF CULTURED GC CELLS BY ACTION EARLY IN THE Gl PERIOD.

1984 • 26 citations

Thyroid hormone action in pituitary cells. Differences in the regulation of thyrotropin-releasing hormone receptors and growth hormone synthesis.

1979 • 21 citations

L-triiodothyronine stimulates growth by means of an autocrine factor in a cultured growth-hormone-producing cell line.

1987 • 21 citations

Regulation of growth hormone mRNA synthesis by 3,5,3'-triiodo-L-thyronine in cultured growth hormone-producing rat pituitary tumor cells (GC cells). Dissociation between nuclear iodothyronine receptor concentration and growth hormone mRNA synthesis during the deoxyribonucleic acid synthesis phase of the cell cycle.

1985 • 18 citations

Induction of amino acid transport by L-triiodothyronine in cultured growth hormone-producing rat pituitary tumor cells (GC cells).

1984 • 15 citations

5,5′-Diphenylhydantoin (Phenytoin) Attenuates the Action of 3,5,3′-Triiodo-L-Thyronine in Cultured GC Cells*

1985 • 11 citations

Development and Characterization of a Variant GC Cell Line with L-Triiodothyronine-Independent Growth and Growth Hormone Production

1989 • 2 citations

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L-Triiodothyronine (T3) Regulates Cellular Growth Rate, Growth Hormone Production, and… (1990) – Endocrinology | Metascience Observatory Explorer