Anchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein.
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References (63)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1970 • 253,849 citations
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 • 47,043 citations
Calcium's Role in Mechanotransduction during Muscle Development
2014 • 14,293 citations
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 • 9,986 citations
Phase separation of integral membrane proteins in Triton X-114 solution.
1981 • 3,366 citations
Integrins and Signal Transduction Pathways: the Road Taken
1995 • 3,002 citations
Signal transduction from the extracellular matrix.
1993 • 1,727 citations
pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.
1992 • 1,456 citations
Regulation of development and differentiation by the extracellular matrix
1993 • 1,216 citations
Calcium-Regulated Differentiation of Normal Human Epidermal Keratinocytes in Chemically Defined Clonal Culture and Serum-Free Serial Culture
1983 • 1,088 citations
Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.
1989 • 1,073 citations
Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function
1995 • 900 citations
Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes
1991 • 771 citations
Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments.
1991 • 755 citations
Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase.
1992 • 743 citations
Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits.
1987 • 727 citations
Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.
1991 • 713 citations
Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity.
1991 • 659 citations
Epidermal differentiation: the bare essentials.
1990 • 651 citations
The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells.
1990 • 629 citations
Multi‐faceted regulation of cell differentiation by extracellular matrix
1993 • 610 citations
Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein.
1991 • 578 citations
Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.
1991 • 574 citations
Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information
1992 • 532 citations
Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex.
1993 • 510 citations
Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes.
1990 • 486 citations
Distinct functions for integrins alpha 3 beta 1 in focal adhesions and alpha 6 beta 4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: relation to hemidesmosomes.
1990 • 462 citations
Focal adhesion kinase (p125FAK): A point of convergence in the action of neuropeptides, integrins, and oncogenes
1992 • 453 citations
The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifically inhibit cell adhesion to fibronectin and react with platelet glycoproteins Ic-IIa.
1988 • 446 citations
A Link Between Cyclin A Expression and Adhesion-Dependent Cell Cycle Progression
1993 • 399 citations
Characterization of the class III collagen receptor, a phosphorylated, transmembrane glycoprotein expressed in nucleated human cells.
1988 • 382 citations
Platelet-derived growth factor modulation of focal adhesion kinase (p125FAK) and paxillin tyrosine phosphorylation in Swiss 3T3 cells. Bell-shaped dose response and cross-talk with bombesin.
1994 • 305 citations
Epiligrin, the major human keratinocyte integrin ligand, is a target in both an acquired autoimmune and an inherited subepidermal blistering skin disease.
1992 • 286 citations
Cloning of the LamA3 gene encoding the alpha 3 chain of the adhesive ligand epiligrin. Expression in wound repair.
1994 • 282 citations
Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes.
2000 • 241 citations
Control of intracellular pH and growth by fibronectin in capillary endothelial cells.
1990 • 241 citations
A function for the integrin alpha 6 beta 4 in the hemidesmosome.
1991 • 225 citations
Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein.
1989 • 223 citations
Wound repair, keratinocyte activation and integrin modulation
1992 • 219 citations
Monocyte adherence results in selective induction of novel genes sharing homology with mediators of inflammation and tissue repair.
1990 • 190 citations
Monoclonal antibody GB3, a new probe for the study of human basement membranes and hemidesmosomes
1987 • 185 citations
Focal adhesion kinase: an integrin-linked protein tyrosine kinase
1993 • 177 citations
Surface relocation of alpha 6 beta 4 integrins and assembly of hemidesmosomes in an in vitro model of wound healing.
1991 • 168 citations
Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for alpha 3 beta 1 positive T lymphocytes.
1993 • 165 citations
Monoclonal antibody GB3 defines a widespread defect of several basement membranes and a keratinocyte dysfunction in patients with lethal junctional epidermolysis bullosa.
1991 • 157 citations
Extracellular matrix alters epithelial differentiation
1993 • 156 citations
The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes.
1994 • 117 citations
Immortalization of Primary Human Epithelial Cells by Cloned Cervical Carcinoma DNA Containing Human Papillomavirus Type 16 E6/E7 Open Reading Frames
1989 • 108 citations
Increased tyrosine kinase activity of c-Src during calcium-induced keratinocyte differentiation.
1992 • 105 citations
Formation of hemidesmosomes in cells of a transformed murine mammary tumor cell line and mechanisms involved in adherence of these cells to laminin and kalinin
1993 • 105 citations
Redistribution of the Hemidesmosome Components α6β4 Integrin and Bullous Pemphigoid Antigens during Epithelial Wound Healing
1993 • 97 citations
Expression of the integrin α6β4 in peripheral nerves: localization in schwann and perineural cells and different variants of the β4 subunit
1994 • 91 citations
Workshop on the Pathogenesis of Chronic Wounds
1994 • 87 citations
Junctional Epidermolysis Bullosis: Defects in Expression of Epiligrin/Nicein/Kalinin and Integrin ß4 That Inhibit Hemidesmosome Formation
1994 • 84 citations
Tyrosine phosphorylation is an early and specific event involved in primary keratinocyte differentiation.
1990 • 77 citations
Intermediate filament plasma membrane interactions
1991 • 65 citations
Signals from focal adhesions
1992 • 55 citations
Specific changes of Ras GTPase-activating protein (GAP) and a GAP-associated p62 protein during calcium-induced keratinocyte differentiation.
1992 • 49 citations
Hemidesmosomes in the epithelial cell line 804G: Their fate during wound closure, mitosis and drug induced reorganization of the cytoskeleton
1992 • 38 citations
Integrin expression and differentiation in transformed human epidermal cells is regulated by fibroblasts
1992 • 37 citations
Tyrosine Phosphorylation Is an Early and Specific Event Involved in Primary Keratinocyte Differentiation
1990 • 19 citations
Specific Changes of Ras GTPase-Activating Protein (GAP) and a GAP-Associated p62 Protein during Calcium-Induced Keratinocyte Differentiation
1992 • 9 citations
Deleted Work
1955 • 0 citations