Cellular Transcription Factors Enhance Herpes Simplex Virus Type 1 oriS-Dependent DNA Replication

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Promoter-specific activation of RNA polymerase II transcription by Sp1

1986 • 1,054 citations

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

1983 • 779 citations

High-Efficiency Transformation of Mammalian Cells by Plasmid DNA

1987 • 729 citations

Sp1-mediated transcriptional activation is repressed by Sp3.

1994 • 692 citations

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

1990 • 677 citations

The DNA sequence of equine herpesvirus-1

1992 • 644 citations

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

1992 • 577 citations

Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression.

1992 • 533 citations

The herpes simplex virus amplicon: A new eucaryotic defective-virus cloning-amplifying vector

1982 • 507 citations

A putative origin of replication of plasmids derived from Epstein-Barr virus is composed of two cis-acting components.

1985 • 442 citations

Distinct Regions of Sp1 Modulate DNA Binding and Transcriptional Activation

1988 • 389 citations

Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus

1988 • 386 citations

A complex formed between cell components and an HSV structural polypeptide binds to a viral immediate early gene regulatory DNA sequence

1988 • 360 citations

Transcriptional elements as components of eukaryotic origins of DNA replication

1988 • 341 citations

The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication

1993 • 329 citations

Identification of herpes simplex virus type 1 genes required for origin-dependent DNA synthesis

1988 • 328 citations

Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16.

1988 • 289 citations

Sp1 binds to promoter sequences and activates herpes simplex virus ‘immediate-early’ gene transcription in vitro

1985 • 289 citations

EUKARYOTIC DNA REPLICATION: Anatomy of An Origin

1993 • 280 citations

Activation of Immediate-Early, Early, and Late Promoters by Temperature-Sensitive and Wild-Type Forms of Herpes Simplex Virus Type 1 Protein ICP4

1985 • 273 citations

Polyoma virus DNA replication requires an enhancer

1984 • 253 citations

A method for identifying the viral genes required for herpesvirus DNA replication.

1986 • 228 citations

Cloning, sequencing, and functional analysis of oriL, a herpes simplex virus type 1 origin of DNA synthesis.

1985 • 222 citations

Multiple EBNA1-binding sites are required to form an EBNA1-dependent enhancer and to activate a minimal replicative origin within oriP of Epstein-Barr virus

1989 • 217 citations

The transactivator proteins VP16 and GAL4 bind replication factor A

1993 • 216 citations

A DNA cassette containing a trimerized SV40 polyadenylation signal which efficiently blocks spurious plasmid-initiated transcription.

1989 • 215 citations

Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression.

1995 • 212 citations

Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpression.

1993 • 203 citations

Characterization of the TRs/IRS origin of DNA replication of herpes simplex virus Type 1

1983 • 202 citations

A Putative Origin of Replication of Plasmids Derived from Epstein-Barr Virus Is Composed of Two cis-Acting Components

1985 • 182 citations

Herpes simplex virus DNA replication: the UL9 gene encodes an origin-binding protein.

1988 • 179 citations

Localization of an origin of DNA replication within the TRS/IRS repeated region of the herpes simplex virus type 1 genome.

1982 • 172 citations

Sequence-specific interactions between cellular DNA-binding proteins and the adenovirus origin of DNA replication.

1987 • 169 citations

Functional interactions of the simian virus 40 core origin of replication with flanking regulatory sequences

1986 • 166 citations

Functional organization of the simian virus 40 origin of DNA replication.

1986 • 157 citations

Replication of herpes simplex virus DNA: localization of replication recognition signals within defective virus genomes.

1981 • 155 citations

Negative regulation of Sp1 trans-activation is correlated with the binding of cellular proteins to the amino terminus of the Sp1 trans-activation domain.

1994 • 128 citations

Interaction of origin binding protein with an origin of replication of herpes simplex virus 1.

1988 • 118 citations

Overlapping octamer and TAATGARAT motifs in the VF65-response elements in herpes simplex virus immediate-early promoters represent independent binding sites for cellular nuclear factor III

1989 • 114 citations

Cloning of GT Box-Binding Proteins: A Novel Spl Multigene Family Regulating T-Cell Receptor Gene Expression

1992 • 114 citations

Analysis of DNA sequences which regulate the transcription of a herpes simplex virus immediate early gene

1984 • 113 citations

Cloning, Sequencing, and Functional Analysis of ori_L, a Herpes Simplex Virus Type 1 Origin of DNA Synthesis

1985 • 112 citations

Identification of a Varicella-Zoster Virus Origin of DNA Replication and Its Activation by Herpes Simplex Virus Type 1 Gene Products

1986 • 100 citations

Transient replication of bovine papilloma virus type 1 plasmids: cis and trans requirements.

1986 • 99 citations

Functional Organization of the Simian Virus 40 Origin of DNA Replication

1986 • 89 citations

Adenovirus origin of DNA replication: sequence requirements for replication in vitro.

1987 • 87 citations

Construction and properties of a recombinant herpes simplex virus 1 lacking both S-component origins of DNA synthesis

1993 • 86 citations

Activation of gene expression by herpes simplex virus type 1 ICP0 occurs at the level of mRNA synthesis

1997 • 85 citations

A subset of herpes simplex virus replication genes induces DNA amplification within the host cell genome

1989 • 85 citations

The origin binding protein of herpes simplex virus 1 binds cooperatively to the viral origin of replication oris.

1990 • 83 citations

Analysis of DNA sequences which regulate the transcription of herpes simplex virus immediate early gene 3: DNA sequences required for enhancer-like activity and response to trans-activation by a virion polypeptide

1986 • 82 citations

Binding of the herpes simplex virus type 1 UL9 gene product to an origin of viral DNA replication

1989 • 81 citations

Replication origins and a sequence involved in coordinate induction of the immedlate-early gene family are conserved in an intergenic region of herpes simplex virus

1984 • 78 citations

A Promoter with an Internal Regulatory Domain Is Part of the Origin of Replication in BPV-1

1987 • 78 citations

Rolling circle DNA replication in vitro by a complex of herpes simplex virus type 1-encoded enzymes.

1994 • 74 citations

Herpes simplex virus type 1 oriL is not required for virus replication or for the establishment and reactivation of latent infection in mice

1987 • 73 citations

Sequence-Specific Interactions Between Cellular DNA-Binding Proteins and the Adenovirus origin of DNA Replication

1987 • 73 citations

Bidirectional promoter elements of simian virus 40 are required for efficient replication of the viral DNA.

1986 • 70 citations

Elements in the transcriptional regulatory region flanking herpes simplex virus type 1 oriS stimulate origin function

1991 • 67 citations

Simian Virus 40 DNA Replication: Functional Organization of Regulatory Elements

1986 • 60 citations

BICP22 of bovine herpesvirus 1 is encoded by a spliced 1.7 kb RNA which exhibits immediate early and late transcription kinetics

1994 • 58 citations

Sequence and Structural Requirements of a Herpes Simplex Viral DNA Replication Origin

1988 • 57 citations

Transcriptional analysis of the region of the herpes simplex virus type 1 genome containing the UL8, UL9, and UL10 genes and identification of a novel delayed-early gene product, OBPC

1994 • 57 citations

Differential effects of nerve growth factor and dexamethasone on herpes simplex virus type 1 oriL- and oriS-dependent DNA replication in PC12 cells

1997 • 56 citations

Functional mapping and DNA sequence of an equine herpesvirus 1 origin of replication

1989 • 52 citations

The virulence-determining genomic BamHI fragment 4 of pseudorabies virus contains genes corresponding to the UL15 (partial), UL18, UL19, UL20, and UL21 genes of herpes simplex virus and a putative origin of replication

1992 • 50 citations

DNA replication and chromatin structure of simian virus 40 insertion mutants.

1984 • 49 citations

Rolling circle DNA replication by extracts of herpes simplex virus type 1-infected human cells

1996 • 46 citations

Eukaryotic replication origins

1992 • 44 citations

DNA Sequence of the Major Inverted Repeat in the Varicella-Zoster Virus Genome

1985 • 43 citations

Bidirectional Promoter Elements of Simian Virus 40 Are Required for Efficient Replication of the Viral DNA

1986 • 43 citations

Effects of position and orientation of the 72-base-pair-repeat transcriptional enhancer on replication from the simian virus 40 core origin

1987 • 41 citations

Herpes simplex virus type 1 origin-specific binding protein: oriS-binding properties and effects of cellular proteins

1991 • 37 citations

DNA Replication and Chromatin Structure of Simian Virus 40 Insertion Mutants

1984 • 36 citations

Cellular protein interactions with herpes simplex virus type 1 oriS.

1994 • 33 citations

Adenovirus Origin of DNA Replication: Sequence Requirements for Replication In Vitro

1987 • 33 citations

Analysis of the herpes simplex virus type 1 OriS sequence: mapping of functional domains

1991 • 30 citations

Effects of orientation and position on the activity of a herpes simplex virus immediate early gene far-upstream region

1984 • 29 citations

Cloning and characterization of herpes simplex virus type 1 oriL: comparison of replication and protein-DNA complex formation by oriL and oriS

1995 • 29 citations

Cloning, sequencing, and functional analysis of a Marek's disease virus origin of DNA replication

1991 • 26 citations

Herpes simplex virus DNA synthesis at a preformed replication fork in vitro

1990 • 23 citations

Identification of cis-acting sequences in the promoter of the herpes simplex virus type 1 latency-associated transcripts required for activation by nerve growth factor and sodium butyrate in PC12 cells

1996 • 20 citations

Cellular Protein Interactions with Herpes Simplex Virus Type 1 OriS

1994 • 17 citations

Properties of the novel herpes simplex virus type 1 origin binding protein, OBPC

1996 • 16 citations