Glycine cytoprotection during lethal hepatocellular injury from adenosine triphosphate depletion

Diseases of the Liver and Biliary System

2001 • 1,882 citations

The Liver: Biology and Pathobiology.

1983 • 1,628 citations

Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes

1987 • 533 citations

Molecular Biology of the Cell

1984 • 526 citations

Inhibition of proteolysis protects hippocampal neurons from ischemia.

1991 • 363 citations

The Liver: Biology and Pathobiology

1989 • 293 citations

Cytoprotective effects of glycine and glutathione against hypoxic injury to renal tubules.

1987 • 274 citations

The isolated perfused rat liver: Conceptual and practical considerations

1986 • 271 citations

Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes

1988 • 265 citations

Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death.

1989 • 252 citations

Cystamine induces toxicity in hepatocytes through the elevation of cytosolic Ca2+ and the stimulation of a nonlysosomal proteolytic system.

1986 • 249 citations

[51] Protein degradation as an index of oxidative stress

1990 • 245 citations

Amino acid transport in isolated rat hepatocytes

1982 • 213 citations

Plasma membrane bleb formation and rupture: A common feature of hepatocellular injury

1990 • 209 citations

Hydroperoxides and Thiol Oxidants in the Study of Oxidative Stress in Intact Cells and Organs

1985 • 165 citations

The Liver

1989 • 143 citations

New, simple models to evaluate zone-specific damage due to hypoxia in the perfused rat liver: time course and effect of nutritional state.

1986 • 103 citations

Effects of amino acids, ammonia and leupeptin on protein synthesis and degradation in isolated rat hepatocytes

1978 • 101 citations

Fructose prevents hypoxic cell death in liver

1987 • 98 citations

Intracellular glutathione in the protection from anoxic injury in renal proximal tubules.

1990 • 90 citations

Structural requirements for protection by small amino acids against hypoxic injury in kidney proximal tubules ¹

1990 • 81 citations

ATP depletion and loss of cell integrity in anoxic hepatocytes and silica-treated P388D1 macrophages

1985 • 65 citations

Efflux of protons from acidic vesicles contributes to cytosolic acidification of hepatocytes during ATP depletion

1991 • 58 citations

GLYCINE AND ALANINE CONCENTRATIONS OF BODY FLUIDS; EXPERIMENTAL MODIFICATION

1947 • 51 citations

Decreased loss of liver adenosine triphosphate during hypothermic preservation in rats pretreated with glucose: Implications for organ donor management

1988 • 50 citations

Regulation of the glycine cleavage system in isolated rat liver mitochondria.

1983 • 47 citations

Diseases of the Liver and Biliary System.

1988 • 46 citations

Calcium‐associated cytoprotective effect of taurine on the calcium and oxygen paradoxes in isolated rat hepatocytes

1990 • 43 citations

Amino acid control of proteolysis in perfused livers of synchronously fed rats. Mechanism and specificity of alanine co-regulation.

1991 • 39 citations

Ruthenium red delays the onset of cell death during oxidative stress of rat hepatocytes

1992 • 38 citations

Calcium-dependent proteolysis and its inhibition in the ischemic rat myocardium.

1986 • 35 citations

System a transport activity in normal rat hepatocytes and transformed liver cells: Substrate protection from inactivation by sulfhydryl-modifying reagents

1986 • 29 citations

The Liver and Intracellular Digestion: How Liver Cells Eat!

1989 • 25 citations

Response of autophagic protein degradation to physiologic and pathologic stimuli in rat hepatocyte monolayer cultures.

1988 • 18 citations

Inhibition by aminoacetonitrile and propargylamine of glycine cleavage system from rat brain and liver mitochondria

1983 • 1 citations