The biology of vision of Drosophila.

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures

1980 • 2,218 citations

Molecular characterization of the drosophila trp locus: A putative integral membrane protein required for phototransduction

1989 • 1,119 citations

The 2.2 Å crystal structure of transducin-α complexed with GTPγS

1993 • 788 citations

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors

1992 • 732 citations

Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin

1983 • 689 citations

BEHAVIORAL MUTANTS OF Drosophila ISOLATED BY COUNTERCURRENT DISTRIBUTION

1967 • 666 citations

Isolation of a putative phospholipase c gene of drosophila, norpA, and its role in phototransduction

1988 • 665 citations

Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel

1989 • 663 citations

Fluorescent Probes of Cell Signaling

1989 • 649 citations

Abnormal Electroretinogram from a Drosophila Mutant

1969 • 642 citations

The Drosophila ninaE gene encodes an opsin

1985 • 545 citations

Isolation and structure of a rhodopsin gene from D. melanogaster

1985 • 481 citations

Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene

1992 • 441 citations

Genetic dissection of the photoreceptor system in the compound eye of Drosophila melanogaster

1976 • 395 citations

The cyclophilin homolog ninaA is required in the secretory pathway

1991 • 330 citations

Arrestin Function in Inactivation of G Protein-Coupled Receptor Rhodopsin in Vivo

1993 • 313 citations

The cyclophilin homolog NinaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin.

1994 • 305 citations

The calcium feedback signal in the phototransduction cascade of vertebrate rods

1994 • 290 citations

The cyclophilin homolog ninaA is a tissue-specific integral membrane protein required for the proper synthesis of a subset of Drosophila rhodopsins

1991 • 271 citations

Novel Ca2+ channels underlying transduction in Drosophila photoreceptors: implications for phosphoinositide-mediated Ca2+ mobilization

1993 • 262 citations

Induction of photoreceptor voltage noise in the dark in Drosophila mutant

1975 • 254 citations

Photoreceptor Deactivation and Retinal Degeneration Mediated by a Photoreceptor-Specific Protein Kinase C

1991 • 240 citations

Defective intracellular transport is the molecular basis of rhodopsin-dependent dominant retinal degeneration.

1995 • 239 citations

Tracing the roots of ion channels

1992 • 235 citations

The concentration of cytosolic free calcium in vertebrate rod outer segments measured with fura-2

1988 • 234 citations

Mutants of the Visual Pathway of Drosophila melanogaster

1970 • 190 citations

Neurogenetics : genetic approaches to the nervous system

1979 • 188 citations

A Drosophila mutant defective in extracellular calcium-dependent photoreceptor deactivation and rapid desensitization

1991 • 186 citations

Gqα protein function in vivo: Genetic dissection of its role in photoreceptor cell physiology

1995 • 179 citations

Signal Transduction in Drosophila Photoreceptors

1995 • 178 citations

Regulation of PLC-mediated signalling in vivo by CDP-diacylglycerol synthase

1995 • 169 citations

Cytosolic calcium transients: Spatial localization and role in drosophila photoreceptor cell function

1994 • 143 citations

Ectopic expression of ultraviolet-rhodopsins in the blue photoreceptor cells of Drosophila: visual physiology and photochemistry of transgenic animals

1992 • 139 citations

The light response of drosophila photoreceptors is accompanied by an increase in cellular calcium: Effects of specific mutations

1994 • 137 citations

dgq: A drosophila gene encoding a visual system-specific Gα molecule

1990 • 137 citations

Neuronal Ca2+ signalling takes the local route

1992 • 127 citations

Photolysis of caged Ca2+ facilitates and inactivates but does not directly excite light-sensitive channels in Drosophila photoreceptors

1995 • 112 citations

Light-induced reduction in excitation efficiency in the trp mutant of Drosophila.

1982 • 110 citations

Cyclophilins: a new family of proteins involved in intracellular folding

1992 • 100 citations

Rhodopsin and autosomal dominant retinitis pigmentosa

1992 • 96 citations

Genetic dissection of light-induced Ca2+ influx into Drosophila photoreceptors.

1994 • 74 citations

Signal Transduction in the Visual System of Drosophila

1991 • 69 citations

Spontaneous activation of light-sensitive channels in Drosophila photoreceptors.

1994 • 68 citations

An eye-specific Gβ subunit essential for termination of the phototransduction cascade

1994 • 66 citations

Ca²⁺limits the development of the light response inDrosophilaphotoreceptors

1993 • 44 citations

Phototransduction in itDrosophila: a paradigm for the genetic dissection of sensory transduction cascades

1992 • 22 citations