HIV-1 Vif Blocks the Antiviral Activity of APOBEC3G by Impairing Both Its Translation and Intracellular Stability

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

2002 • 2,276 citations

Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

2003 • 1,456 citations

DNA Deamination Mediates Innate Immunity to Retroviral Infection

2003 • 1,219 citations

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

2003 • 1,046 citations

E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.

1996 • 904 citations

Species-Specific Exclusion of APOBEC3G from HIV-1 Virions by Vif

2003 • 884 citations

Hypermutation of HIV-1 DNA in the Absence of the Vif Protein

2003 • 641 citations

Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex.

1982 • 580 citations

RNA Editing Enzyme APOBEC1 and Some of Its Homologs Can Act as DNA Mutators

2002 • 565 citations

The HIV A (sor) gene product is essential for virus infectivity

1987 • 475 citations

Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells

1993 • 449 citations

Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes

1992 • 447 citations

The V Protein of Simian Virus 5 Inhibits Interferon Signalling by Targeting STAT1 for Proteasome-Mediated Degradation

1999 • 416 citations

The sor Gene of HIV-1 Is Required for Efficient Virus Transmission in Vitro

1987 • 365 citations

The Human Papillomavirus Type 16 E6 Oncoprotein Can Down-Regulate p53 Activity by Targeting the Transcriptional Coactivator CBP/p300

1999 • 325 citations

Evidence for a newly discovered cellular anti-HIV-1 phenotype

1998 • 273 citations

An Endogenous Inhibitor of Human Immunodeficiency Virus in Human Lymphocytes Is Overcome by the Viral Vif Protein

1998 • 238 citations

A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

1998 • 227 citations

Identification of Highly Attenuated Mutants of Simian Immunodeficiency Virus

1998 • 226 citations

Highly Purified Human Immunodeficiency Virus Type 1 Reveals a Virtual Absence of Vif in Virions

1999 • 206 citations

Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles

1993 • 188 citations

Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1

1993 • 177 citations

Human Immunodeficiency Virus Type 1 Vif Protein Is Packaged into the Nucleoprotein Complex through an Interaction with Viral Genomic RNA

2001 • 137 citations

Efficient Cleavage of Ribosome-Associated Poly(A)-Binding Protein by Enterovirus 3C Protease

2002 • 134 citations

Subcellular localization of the Vif protein of human immunodeficiency virus type 1

1994 • 132 citations

HIV-1 Vpr Enhances Viral Burden by Facilitating Infection of Tissue Macrophages but Not Nondividing CD4+ T Cells

2001 • 129 citations

Proteolysis of the p220 component of the cap-binding protein complex is not sufficient for complete inhibition of host cell protein synthesis after poliovirus infection

1987 • 114 citations

Generation and characterization of the human immunodeficiency virus type 1 mutants

1991 • 88 citations

The Predominant eIF4G-Specific Cleavage Activity in Poliovirus-Infected HeLa Cells Is Distinct from 2A Protease

1998 • 50 citations

Eukaryotic GST fusion vector for the study of protein-protein associations in vivo: application to interaction of ATFa with Jun and Fos.

1995 • 48 citations