DNA Deamination Mediates Innate Immunity to Retroviral Infection

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

2002 • 2,276 citations

Quality Control by DNA Repair

1999 • 1,469 citations

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

2003 • 723 citations

An Anthropoid-Specific Locus of Orphan C to U RNA-Editing Enzymes on Chromosome 22

2002 • 689 citations

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

2003 • 662 citations

Hypermutation of HIV-1 DNA in the Absence of the Vif Protein

2003 • 641 citations

Molecular Cloning of an Apolipoprotein B Messenger RNA Editing Protein

1993 • 609 citations

RNA Editing Enzyme APOBEC1 and Some of Its Homologs Can Act as DNA Mutators

2002 • 565 citations

The HIV A (sor) gene product is essential for virus infectivity

1987 • 475 citations

Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells

1993 • 449 citations

The sor Gene of HIV-1 Is Required for Efficient Virus Transmission in Vitro

1987 • 365 citations

Evidence for a newly discovered cellular anti-HIV-1 phenotype

1998 • 273 citations

An Endogenous Inhibitor of Human Immunodeficiency Virus in Human Lymphocytes Is Overcome by the Viral Vif Protein

1998 • 238 citations

Immunity through DNA deamination

2003 • 235 citations

The human immunodeficiency virus type 1 Vif protein modulates the postpenetration stability of viral nucleoprotein complexes

1996 • 189 citations

Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1

1993 • 177 citations

Human Immunodeficiency Virus Type 1 DNA Sequences Genetically Damaged by Hypermutation Are Often Abundant in Patient Peripheral Blood Mononuclear Cells and May Be Generated during Near-Simultaneous Infection and Activation of CD4 ⁺ T Cells

2001 • 174 citations

In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

2003 • 143 citations

The regulation of primate immunodeficiency virus infectivity by Vif is cell species restricted: a role for Vif in determining virus host range and cross-species transmission

1998 • 142 citations

G-->A hypermutation of the human immunodeficiency virus type 1 genome: evidence for dCTP pool imbalance during reverse transcription.

1994 • 140 citations

Use of a Transient Assay for Studying the Genetic Determinants of Fv1 Restriction

2000 • 132 citations

Incorporation of Uracil into Minus Strand DNA Affects the Specificity of Plus Strand Synthesis Initiation during Lentiviral Reverse Transcription

2003 • 75 citations