E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product

1989 • 3,036 citations

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1993 • 2,329 citations

The E2F transcription factor is a cellular target for the RB protein

1991 • 1,461 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

In vivo ubiquitination and proteasome-mediated degradation of p53(1).

1996 • 643 citations

SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family

1989 • 508 citations

Degradation of nuclear oncoproteins by the ubiquitin system in vitro.

1991 • 345 citations

Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway.

1994 • 274 citations

Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.

1994 • 243 citations

Cleavage of retinoblastoma protein during apoptosis: an interleukin 1 beta-converting enzyme-like protease as candidate.

1996 • 204 citations

Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.

1995 • 178 citations

Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes

1992 • 177 citations

Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins.

1992 • 117 citations

Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein

1993 • 80 citations