Active repression by unliganded retinoid receptors in development

Transcriptional Regulatory Networks in Saccharomyces cerevisiae

2002 • 2,967 citations

The coregulator exchange in transcriptional functions of nuclear receptors

2000 • 2,219 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

Genome-Wide Location and Function of DNA Binding Proteins

2000 • 1,720 citations

Function of the retinoic acid receptors (RARs) during development: (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants

1994 • 987 citations

Retinoids in Embryonal Development

2000 • 859 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

Function of the retinoic acid receptors (RARs) during development: (I) Craniofacial and skeletal abnormalities in RAR double mutants

1994 • 755 citations

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

2002 • 746 citations

Stage-related capacity for limb chondrogenesis in cell culture

1977 • 616 citations

The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

1993 • 602 citations

Polarity-specific activities of retinoic acid receptors determined by a co-repressor

1995 • 569 citations

The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures

2001 • 550 citations

Combinatorial Roles of the Nuclear Receptor Corepressor in Transcription and Development

2000 • 502 citations

Ectodermal Patterning in Vertebrate Embryos

1997 • 457 citations

NuRD and SIN3

2000 • 384 citations

Multiple functions of vitamin A.

1984 • 367 citations

Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha).

1990 • 330 citations

The function and evolution of Msx genes: pointers and paradoxes

1995 • 327 citations

Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway

2000 • 317 citations

N-CoR controls differentiation of neural stem cells into astrocytes

2002 • 305 citations

Co-regulator recruitment and the mechanism of retinoic acid receptor synergy

2002 • 300 citations

Function of Vitamin A in Vertebrate Embryonic Development

2001 • 254 citations

Roles for Msx and Dlx homeoproteins in vertebrate development

2000 • 250 citations

Ligand-Dependent Nuclear Receptor Corepressor LCoR Functions by Histone Deacetylase-Dependent and -Independent Mechanisms

2003 • 248 citations

SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers.

1996 • 244 citations

Transcriptional Coregulators in Development

1999 • 242 citations

An essential role for retinoid signaling in anteroposterior neural patterning

1997 • 236 citations

A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage.

1993 • 233 citations

Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development

2002 • 231 citations

An unliganded thyroid hormone receptor causes severe neurological dysfunction

2001 • 227 citations

Translocations of the RARα gene in acute promyelocytic leukemia

2001 • 210 citations

Msx homeobox genes inhibit differentiation through upregulation ofcyclin D1

2001 • 206 citations

Vitamin A and Embryonic Development: An Overview ,

1998 • 190 citations

Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis

2002 • 189 citations

Regionalized metabolic activity establishes boundaries of retinoic acid signalling

1998 • 171 citations

Transcriptional regulation in acute promyelocytic leukemia

2001 • 160 citations

Requirement for RAR-mediated gene repression in skeletal progenitor differentiation

2002 • 154 citations

Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription

2000 • 146 citations

Retinoic acid and retinoic acid receptors in development

1995 • 138 citations

Regulation of Skeletal Progenitor Differentiation by the Bmp and Retinoid Signaling Pathways

2000 • 137 citations

Active repression of RAR signaling is required for head formation

2001 • 127 citations

Retinoic Acid Receptors

1995 • 123 citations

A genetic dissection of the retinoid signalling pathway in the mouse

1999 • 120 citations

A direct screen for secreted proteins in Xenopus embryos identifies distinct activities for the Wnt antagonists Crescent and Frzb-1

2000 • 116 citations

The PML-RAR alpha gene product of the t(15;17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells.

1994 • 107 citations

A retinoic acid receptor expressed in the early development of Xenopus laevis.

1991 • 106 citations

Retinoic Acid Receptor α Function in Vertebrate Limb Skeletogenesis: a Modulator of Chondrogenesis

1997 • 94 citations

Nuclear Receptor Corepressor Recruitment by Unliganded Thyroid Hormone Receptor in Gene Repression during Xenopus laevis Development

2002 • 94 citations

Retinoic Acid Receptors β and γ Do Not Repress, But Instead Activate Target Gene Transcription in Both the Absence and Presence of Hormone Ligand

2003 • 66 citations

Retinoic acid receptor antagonism in vivo expands the numbers of precursor cells during granulopoiesis

2002 • 59 citations

Retinoids and their receptors in skeletal development

1998 • 53 citations

Retinoic Acid-Induced Granulocytic Differentiation of HL-60 Myeloid Leukemia Cells Is Mediated Directly through the Retinoic Acid Receptor (RAR-α)

1990 • 52 citations

Promoter of FGF8 Reveals a Unique Regulation by Unliganded RARα

2002 • 49 citations

Regional specificity of RARγ isoforms in Xenopus development

1994 • 33 citations

The pattern of retinoic acid receptor γ (RARγ) expression in normal development of Xenopus laevis and after manipulation of the main body axis

1993 • 30 citations

Involvement of histone deacetylase at two distinct steps in gene regulation during intestinal development in Xenopus laevis

2001 • 29 citations

Overexpression of retinoic acid receptor alpha suppresses myeloid cell differentiation at the promyelocyte stage.

1995 • 29 citations

Characterization of the human MSX-1 promoter and an enhancer responsible for retinoic acid induction.

1994 • 22 citations

Downregulation ofMsx-2Expression Results in Chondrogenesis in the Medial Region of the Avian Mandible

1996 • 18 citations

Retinoids and Mouse Embryonic Development

1995 • 13 citations