A new bipartite DNA-binding domain: cooperative interaction between the cut repeat and homeo domain of the cut homeo proteins.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

The structure and function of the homeodomain

1989 • 1,007 citations

Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions

1990 • 996 citations

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

1988 • 750 citations

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 • 733 citations

Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo-and a Cys–His domain

1990 • 684 citations

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

1988 • 670 citations

A structural taxonomy of DNA-binding domains

1991 • 615 citations

Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II

1990 • 550 citations

Crystal structure of a MATα2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions

1991 • 538 citations

A single amino acid can determine the DNA binding specificity of homeodomain proteins

1989 • 531 citations

Divergent homeo box proteins recognize similar DNA sequences in Drosophila

1988 • 491 citations

Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors.

1992 • 491 citations

The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: Comparison with prokaryotic repressors

1989 • 468 citations

Protein-DNA contacts in the structure of a homeodomain-DNA complex determined by nuclear magnetic resonance spectroscopy in solution.

1990 • 460 citations

Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter

1987 • 407 citations

The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1—Pit-1 interactions

1990 • 403 citations

The Phosphorylation State of Eucaryotic Initiation Factor 2 Alters Translational Efficiency of Specific mRNAs

1989 • 393 citations

What determines the specificity of action of Drosophila homeodomain proteins?

1990 • 357 citations

The paired box encodes a second DNA-binding domain in the paired homeo domain protein.

1991 • 349 citations

Expression of homeo box genes during mouse development: a review.

1988 • 331 citations

The POU domain is a bipartite DNA-binding structure

1988 • 304 citations

DNA binding specificity of homeodomains

1991 • 300 citations

Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila

1988 • 289 citations

Patterns of expression of cut, a protein required for external sensory organ development in wild-type and cut mutant Drosophila embryos.

1990 • 284 citations

Cyclic amplification and selection of targets (CASTing) for the myogenin consensus binding site.

1991 • 275 citations

CCAAT displacement protein as a repressor of the myelomonocytic-specific gp91-phox gene promoter.

1991 • 274 citations

The DNA binding specificity of the bipartite POU domain and its subdomains.

1992 • 268 citations

Transformation of sensory organs by Mutations of the cut locus of D. melanogaster

1987 • 265 citations

Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer

1991 • 230 citations

Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut

1992 • 222 citations

Postembryonic patterns of expression of cut, a locus regulating sensory organ identity in Drosophila

1993 • 191 citations

Nucleotides flanking a conserved TAAT core dictate the DNA binding specificity of three murine homeodomain proteins.

1993 • 182 citations

A MyoD1-independent muscle-specific enhancer controls the expression of the beta-myosin heavy chain gene in skeletal and cardiac muscle cells.

1991 • 175 citations

Transformation of sensory organ identity by ectopic expression of Cut in Drosophila.

1991 • 166 citations

Secondary structure determination for the Antennapedia homeodomain by nuclear magnetic resonance and evidence for a helix-turn-helix motif.

1988 • 151 citations

The −117 mutation in Greek HPFH affects the binding of three nuclear factors to the CCAAT region of the gamma-globin gene.

1988 • 143 citations

The oct-1 homeo domain contacts only part of the octamer sequence and full oct-1 DNA-binding activity requires the POU-specific domain.

1990 • 135 citations

A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain.

1992 • 134 citations

The caudal gene product is a direct activator of fushi tarazu transcription during Drosophila embryogenesis

1989 • 133 citations

The homeodomain: A new face for the helix‐turn‐helix?

1992 • 120 citations

Recognition of the surface of a homeo domain protein.

1992 • 115 citations

Drosophila homoeotic genes encode transcriptional activators similar to mammalian OTF-2

1988 • 113 citations

Clox, a mammalian homeobox gene related to Drosophila cut, encodes DNA-binding regulatory proteins differentially expressed during development

1992 • 111 citations

Cyclic amplification and selection of targets for multicomponent complexes: myogenin interacts with factors recognizing binding sites for basic helix-loop-helix, nuclear factor 1, myocyte-specific enhancer-binding factor 2, and COMP1 factor.

1992 • 100 citations

Segments of the POU domain influence one another's DNA-binding specificity.

1992 • 99 citations

Four distinct regulatory regions of the cut locus and their effect on cell type specification in Drosophila.

1991 • 88 citations

Gtx: a novel murine homeobox-containing gene, expressed specifically in glial cells of the brain and germ cells of testis, has a transcriptional repressor activity in vitro for a serum-inducible promoter.

1993 • 88 citations

Homeobox genes in mouse development.

1991 • 83 citations

Homoeo-domain homology in yeast MATα2 is essential for repressor activity

1986 • 57 citations

The protein CDP, but not CP1, footprints on the CCAAT region of the γ-globin gene in unfractionated B-cell extracts

1989 • 54 citations