Scanning the Intracellular S6 Activation Gate in the Shaker K+ Channel

The Structure of the Potassium Channel: Molecular Basis of K ⁺ Conduction and Selectivity

1998 • 6,595 citations

Biophysical and Molecular Mechanisms of Shaker Potassium Channel Inactivation

1990 • 1,528 citations

A Thermodynamic Scale for the Helix-Forming Tendencies of the Commonly Occurring Amino Acids

1990 • 1,173 citations

Influence of proline residues on protein conformation

1991 • 1,125 citations

Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons

1971 • 930 citations

Restoration of Inactivation in Mutants of Shaker Potassium Channels by a Peptide Derived from ShB

1990 • 752 citations

Charge Movement Associated with the Opening and Closing of the Activation Gates of the Na Channels

1974 • 746 citations

Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors

2001 • 557 citations

Structural Rearrangements Underlying K ⁺ -Channel Activation Gating

1999 • 553 citations

Shaker potassium channel gating. III: Evaluation of kinetic models for activation.

1994 • 512 citations

Gated Access to the Pore of a Voltage-Dependent K+ Channel

1997 • 478 citations

Structural Basis of Amino Acid α Helix Propensity

1993 • 467 citations

Inactivation of the Potassium Conductance and Related Phenomena Caused by Quaternary Ammonium Ion Injection in Squid Axons

1969 • 427 citations

Structural Conservation in Prokaryotic and Eukaryotic Potassium Channels

1998 • 401 citations

Electrostatic interactions of S4 voltage sensor in shaker K+ channel

1995 • 366 citations

Blocker protection in the pore of a voltage-gated K+ channel and its structural implications

2000 • 336 citations

Molecular Dynamics of the KcsA K+ Channel in a Bilayer Membrane

2000 • 331 citations

Multiple products of the drosophila Shaker gene may contribute to potassium channel diversity

1988 • 324 citations

Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels

1993 • 317 citations

Ion conduction pore is conserved among potassium channels

2001 • 310 citations

The Inner Quaternary Ammonium Ion Receptor in Potassium Channels of the Node of Ranvier

1972 • 302 citations

Shaker potassium channel gating. II: Transitions in the activation pathway.

1994 • 299 citations

Activation of Shaker Potassium Channels

1998 • 277 citations

Tight Steric Closure at the Intracellular Activation Gate of a Voltage-Gated K+ Channel

2001 • 262 citations

Purification and Characterization of Three Inhibitors of Voltage-Dependent K+ Channels from Leiurus Quinquestriatus var. Hebraeus Venom

1994 • 260 citations

Activation of Shaker Potassium Channels

1998 • 227 citations

Trapping of Organic Blockers by Closing of Voltage-dependent K+ Channels

1997 • 211 citations

The Activation Gate of a Voltage-Gated K+ Channel Can Be Trapped in the Open State by an Intersubunit Metal Bridge

1998 • 202 citations

Structure of the KcsA channel intracellular gate in the open state.

2001 • 196 citations

How Does the W434F Mutation Block Current in Shaker Potassium Channels?

1997 • 190 citations

Shaker potassium channel gating. I: Transitions near the open state.

1994 • 187 citations

Voltage Sensitivity and Gating Charge in Shaker and Shab Family Potassium Channels

1999 • 159 citations

Glycosylation of Shaker Potassium Channel Protein in Insect Cell Culture and in Xenopus Oocytes

1994 • 118 citations

A Localized Interaction Surface for Voltage-Sensing Domains on the Pore Domain of a K+ Channel

2000 • 117 citations

Hanging Gondola Structure of the T1 Domain in a Voltage-Gated K⁺ Channel

2000 • 100 citations

A turn propensity scale for transmembrane helices

1999 • 93 citations

Activation of Shaker Potassium Channels

1998 • 73 citations

Determinants of Voltage-Dependent Gating and Open-State Stability in the S5 Segment of Shaker Potassium Channels

1999 • 43 citations

Conserved cysteine residues in the Shaker K+ channel are not linked by a disulfide bond

1995 • 26 citations